Endothelial cell tumors

Microscopy Research and Technique

Volumn 60, Issue 2, 2003, Pages 165-170

  Bell, Cecil David ^a  

^a ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Congenital malformations; Endothelium; Neoplasms

Indexed keywords

CELL DEATH; CELL PROLIFERATION; DISEASE CONTROL; ENDOTHELIAL CELLS;

CLINICAL COURSE; CONGENITAL MALFORMATIONS; ENDOTHELIAL-CELLS; ENDOTHELIUM; HAEMANGIOMA; NEOPLASM; VASCULAR ABNORMALITIES; VASCULAR LESIONS; VASCULAR TUMOR; VON HIPPEL-LINDAU DISEASE;

TUMORS;

FIBROBLAST GROWTH FACTOR; MATRIX METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOSARCOMA; APOPTOSIS; CONGENITAL BLOOD VESSEL MALFORMATION; GENE MUTATION; HEMANGIOBLASTOMA; HEMANGIOENDOTHELIOMA; HEMANGIOMA; HISTOPATHOLOGY; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; RENDU OSLER WEBER DISEASE; REVIEW; VON HIPPEL LINDAU DISEASE;

EID: 0037301996     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.10254     Document Type: Review

References (68)

1. Arthur HM, Ure J, Smith AJH, Renforth G, Wilson DI, Torsney E, Charlton R, Parums DV, Jowett T, Marchuk DA, Burn J, Diamond AG. 2000. Endoglin, an ancillary TGF beta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. Dev Biol 217:42-53.
2. Azuma H. 2000. Genetic and molecular pathogenesis of hereditary hemorrhagic telangiectasia. J Med Invest 47:81-90.
3. Berg JN, Walter JW, Thisanagayam U, Evans M, Blei F, Waner M, Diamond AG, Marchuk DA, Porteous ME. 2001. Evidence for loss of heterozygosity of 5q in sporadic hemangiomas: are somatic mutations involved in hemangioma formation? J Clin Pathol 54:249-252.
4. Bielenberg DR, Bucana CD, Sanchez R, Mulliken JB, Folkman J, Fidler IJ. 1999. Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta. Int J Oncol 14:401-408.
5. Blei F, Walter J, Orlow S, Marchuk DA. 1998. Familial segregation of hemangiomas and vascular malformations as an autosomal dominant trait. Arch Dermatol 134:718-722.
6. Boon LM, Brouillard P, Irrthum A, Karttunen L, Warman ML, Rudolph R, Mulliken JB, Olsen BR, Vikkula M. 1999. A gene for inherited cutaneous venous anomalies ("glomangiomas") localizes to chromosome 1p21-22. Am J Hum Genet 65:125-133.
7. Boudreau N, Andrews C, Srebrow A, Ravanpay A, Cheresh DA. 1997. Induction of the angiogenic phenotype by Hox D3. J Cell Biol 139:257-264.
8. Brieteneder-Geleff S, Soleiman A, Kowalski H, Horvat R, Amann G, Kriehuber E, Diem K, Weninger W, Tschachler E, Alitalo K, Kerjaschki D. 1999a. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am J Pathol 154:385-394.
9. Brieteneder-Geleff S, Soleiman A, Horvat R, Amann G, Kowalski H, Kerjaschki D. 1999b. Podoplanin- a specific marker for lymphatic endothelium expressed in angiosarcoma. Verh Dtsch Ges Pathol 83:270-275.
10. Brown LF, Dezube BJ, Tognazzi K, Dvorak HF, Yancopoulos GD. 2000. Expression of Tie1, Tie2, and Angiopoietins 1,2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma. Am J Pathol 156:2179-2183.
11. Chang J, Most D, Bresnick S, Mehrawa B, Steinbrech DS, Reinisch J, Longaker MT, Turk AE. 1999. Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis. Plast Reconstr Surg 103:1-9.
12. Cheung DS, Warman ML, Mulliken JB. 1997. Hemangioma in twins. Ann Plast Surg 38:269-274.
13. Clifford SC, Cockman ME, Smallwood AC, Mole DR, Woodward ER, Maxwell PH, Ratcliffe PJ, Maher ER. 2001. Contrasting effects of HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease. Hum Mol Genet 10:1029-1038.
14. Dosanjh A, Chang J, Bresnick S, Zhou L, Reinisch J, Longaker M, Karasek M. 2000. In vitro characteristics of neonatal hemangioma endothelial cells: similarities and differences between normal neonatal and fetal endothelial cells. J Cutan Pathol 27:441-450.
15. Eerola I, Plate KH, Spiegel R, Boon LM, Mulliken JB, Vikkula M. 2000. KRIT1 is mutated in hyperkeratotic cutaneous capillaryvenous malformation associated with cerebral capillary malformation. Hum Mol Genet 9:1351-1355.
16. Eichenfield LF. 1998. Evolving knowledge of hemangiomas and vascular malformations. Arch Derm 134:740-742.
17. Flamme I, Krieg M, Plate KH. 1998. Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2 alpha. Am J Pathol 153:25-29.
18. Folpe AL, Veikkola T, Valtola R, Weiss SW. 2000. Vascular endothelial growth factor receptor-3 (VEGFR-3): a marker of vascular tumors with presumed lymphatic differentiation, including Kaposi's sarcoma, kaposiform and Dabska-type hemangioendotheliomas, and a subset of angiosarcomas. Mod Pathol 13:180-185.
19. Garzon MC, Enjolras O, Frieden IJ. 2000. Vascular tumors and vascular malformations: evidence for an association. J Am Acad Dermatol 42:275-279.
20. Glowacki J, Mulliken JB. 1982. Mast cells in hemangiomas and vascular malformations. Pediatrics 70:48-51.
21. Gray MH, Rosenberg AE, Dickersin GR, Bhan AK. 1990. Cytokeratin expression in epithelioid vascular neoplasms. Hum Pathol 21:212-217.
22. Haase VH, Glickman JN, Socolsky M, Jaenisch R. 2001. Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. PNAS 98:1583-1588.
23. Hasan Q, Ruger BM, Tan ST, Gush J, Davis PF. 2000a. Clusterin/apoJ expression during the development of hemangioma. Hum Pathol 31:691-697.
24. Hasan Q, Tan ST, Gush J, Peters SG, Davis PF. 2000b. Steroid therapy of a proliferating hemangioma: histochemical and molecular changes. Pediatrics 105:117-120.
25. Ikegawa S, Saida T, Nakajima T, Ishihara K. 1992. Immunohisto-chemical studies of blood group antigens ABH in cutaneous angiosarcoma. Am J Dermatopathol 14:100-106.
26. Jang YC, Isik FF, Gibran NS. 2000. Nerve distribution in hemangiomas depends on the proliferative state of the microvasculature. J Surg Res 93:144-148.
27. Karsan A, Yee E, Poirier GG, Zhou P, Craig R, Harlan JM. 1997. Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms. Am J Pathol 151:1775-1784.
28. Kjeldsen AD, Brusgaard K, Poulsen L, Kruse T, Rasmussen K, Green A, Vase P. 2001. Mutations in the ALK-1 gene and the phenotype of hereditary hemorrhagic telangiectasia in two large Danish families. Am J Med Genet 98:298-302.
29. Kraling BM, Razon MJ, Boon LM, Zurakowski D, Seachord C, Darveau RP, Mulliken JB, Corless CL, Bischoff J. 1996. E-selectin is present in proliferating endothelial cells in human hemangiomas. Am J Pathol 148:1181-1191.
30. Kraling BM, Widerschain DG, Boehm T, Rehn M, Mulliken JB, Moses MA. 1999. The role of matrix metalloproteinase activity in the maturation of human capillary endothelial cells in vitro. J Cell Sci 112:1599-1609.
31. Lucas M, Costa AF, Martori M, Solano F, Zayas MD, Izquierdo G. 2001. Germline mutations in the CCM1 gene, encoding KRIT1, cause cerebral cavernous malformations. Ann Neurol 49:529-532.
32. Mancini AJ, Smoller BR. 1996. Proliferation and apoptosis within juvenile capillary hemangiomas. Am J Dermatopathol 18:505-514.
33. Meininger CJ, Brightman SE, Kelly KA, Zetter BR. 1995. Increased stem cell factor release by hemangioma-derived endothelial cells. Lab Invest 72:166-173.
34. Meis-Kindblom JM, Kindblom LG. 1998. Angiosarcoma of soft tissue: a study of 80 cases. Am J Surg Pathol 22:683-697.
35. Mendlick MR, Nelson M, Pickering D, Johansson SL, Seemayer TA, Neff JR, Vergara G, Rosenthal H, Bridge JA. 2001. Am J Surg Pathol 25:684-687.
36. Mentzel T. 1998. Hemangioendotheliomas-evolution of a concept of a heterogeneous group of vascular neoplasms. Verh Dtsch Ges Pathol 82:99-111.
37. Mentzel T, Beham A, Calonje E, Katenkamp D, Fletcher CD. 1997. Epithelioid hemangioendothelioma of skin and soft tissues: clinico-pathologic and immunohistochemical study of 30 cases. Am J Surg Pathol 21:363-374.
38. Miettinen M, Fetsch JF. 2000. Distribution of keratins in normal endothelial cells and a spectrum of vascular tumors: implications in tumor diagnosis. Hum Pathol 31:1009-1010.
39. Miettinen M, Sarlomo-Rikala M, Lasota J. 2000. KIT expression in angiosarcomas and fetal endothelial cells: lack of mutations of exon 11 and exon 17 of C-kit. Mod Pathol 13:536-541.
40. Mulliken JB, Glowacki J. 1982. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg 69:412-420.
41. Mulliken JB, Zetter BR, Folkman J. 1982. In vitro characteristics of endothelium from hemangiomas and vascular malformations. Surgery 92:348-353.
42. Murgia A, Martella M, Vinaanzi C, Polli R, Perilongo G, Opocher G. 2000. Somatic mosaicism in von-Hippel-Lindau disease. Hum Mutat 15:114.
43. Nakamura T. 2000. Apoptosis and expression of Bax/Bcl-2 proteins in pyogenic granuloma: a comparative study with granulation tissue and capillary hemangioma. J Cutan Pathol 27:400-405.
44. Nibbs RJ, Kriehuber E, Ponath PD, Parent D, Qin S, Campbell JD, Henderson A, Kerjaschki D, Maurer D, Graham GJ, Rot A. 2001. The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Am J Pathol 158:867-877.
45. Nor JE, Christensen J, Mooney DJ, Polverini PJ. 1999. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 154:375-384.
46. Nor JE, Christensen J, Liu J, Peters M, Mooney DJ, Strieter RM, Polverini PJ. 2001. Up-regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth. Cancer Res 61:2183-2188.
47. North PE, Waner M, Mizeracki A, Mihm MC Jr. 2000. GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas. Hum Pathol 31:11-22.
48. North PE, Waner M, Mizeracki A, Mrak RE, Nicholas R, Kincannon J, Suen JY, Mihm MC Jr. 2001. A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. Arch Dermatol 137:559-570.
49. Partanen TA, Alitalo K, Miettinen M. 1999. Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors. Cancer 86:2406-2412.
50. Powell J. 1999. Update on hemangiomas and vascular malformations. Curr Opin Pediatr 11:457-463.
51. Razon MJ, Kraling BM, Mulliken JB, Bischoff J. 1998. Increased apoptosis coincides with onset of involution in infantile hemangioma. Microcirculation 5:189-195.
52. Salani D, Taraboletti G, Rosano L, Di Castro V, Borsotti P, Giavazzi R, Bagnato A. 2000. Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Am J Pathol 157:1703-1711.
53. Simonart T, Degraef C, Noel JC, Fokan D, Zhou L, Pradier O, Ducarme M, Schandene L, Van Vooren JP, Parent D, Heenen M. 1998. Overexpression of Bcl-2 in Kaposi's sarcoma-derived cells. J Invest Dermatol 111:349-353.
54. Sirgi KE, Wick MR, Swanson PE. 1993. B72.3 and CD34 immunoreactivity in malignant epithelioid soft tissue tumors. Adjuncts in the recognition of endothelial neoplasms.Am J Surg Pathol 17:179-185.
55. Suster S, Wong TY. 1994.On the discriminatory value of anti-HPCA-1 (CD-34) in the differential diagnosis of benign and malignant cutaneous vascular proliferations. Am J Dermatopathol 16:355-363.
56. Takahashi K, Mulliken JB, Kozakewich HP, Rogers RA, Folkman J, Ezekowiz RA. 1994. Cellular markers that distinguish the phases of hemangioma during infancy and childhood. J Clin Invest 93:2357-2364.
57. Tan ST, Velickovic M, Ruger BM, Davis PF. 2000. Cellular and extracellular markers of hemangioma. Plast Reconstr Surg 106:529-538.
58. Tanioka M, Morita K, Fujii H, Toda KI, Takahashi K, Tanaka T, Nishigori C, Jin G, Higashi S, Toyokuni S, Miyachi Y. 2001. Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions. Br J Dermatol 144:380-383.
59. Tran J, Rak J, Sheehan C, Saibil SD, LaCasse E, Korneluk RG, Kerbel RS. 1999. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochem Biophys Res Commun 264:781-788.
60. Trembath RC, Thomson JR, Machado R, Morgan NV, Atkinson C, Winship I, Simmoneau G, Galie N, Lloyd JE, Humbert M, Nichols WC, Morrell NW. 2001. Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia. N Engl J Med 345:325-334.
61. Vergani V, Garofalo A, Bani MR, Borsotti P, Parker MP, Drudis T, Mazzarol G, Viale G, Giavazzi R, Stetler-Stevenson WG, Taraboletti G. 2001. Inhibition of matrix metalloproteinases by over-expression of tissue inhibitor of metalloproteinase-2 inhibits the growth of experimental hemangiomas. Int J Cancer 91:241-247.
62. rd, Calvert JT, Diamonti AJ, Goumnerov B, Pasyk KA, Marchuk DA, Warman MI, Cantley LC, Mulliken JB, Olsen BR. 1996. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell 87:1181-1190.
63. Walter JW, Blei F, Anderson JL, Orlow SJ, Speer MC, Marchuk DA. 1999. Genetic mapping of a novel familial form of infantile hemangioma. Am J Med Genet 82:77-83.
64. Xiao X, Hong L, Sheng M. 1999. Promoting effect of estrogen on the proliferation of hemangioma vascular endothelial cells in vitro. J Pediatr Surg 34:1603-1605.
65. Zhang J, Clatterbuck RE, Rigamonti D, Dietz HC. 2000. Mutations in KRIT1 in familial cerebral cavernous malformations. Neurosurgery 46:1272-1277.
66. Zhou XP, Marsh DJ, Hampel H, Mulliken JB, Gimm O, Eng C. 2000. Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, atriovenous malformations and lipomatosis. Hum Mol Genet 9:765-768.
67. Zietz C, Rossle M, Haas C, Sendelhofert A, Hirshmann A, Struzl M, Lohrs U. 1998. MDM-2 oncoprotein overexpression, p53 gene mutation, and VEGF up-regulation in angiosarcomas. Am J Pathol 153:1425-1433.
68. Zu Y, Perle MA, Yan Z, Liu J, Kumar A, Waisman J. 2001. Chromosomal abnormalities and p53 gene mutation in a cardiac angiosarcoma. Appl Immunohistochem Mol Morphol 9:24-28.