Antioxidative enzymes in human nasal mucosa after exposure to ozone. Possible role of GSTM1 deficiency

Inflammation Research

Volumn 52, Issue 2, 2003, Pages 51-55

  Otto Knapp, R ^a   Jurgovsky, K ^a   Schierhorn, K ^a   Kunkel, G ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Antioxidative enzymes; GSTM1 deficiency; Nasal mucosa; Ozone

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HISTAMINE; ISOENZYME; OZONE; SUPEROXIDE DISMUTASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME REGULATION; FEMALE; GLUTATHIONE TRANSFERASE DEFICIENCY; HETEROZYGOTE; HUMAN; HUMAN TISSUE; MALE; NASAL BIOPSY; NOSE MUCOSA; PROTEIN FUNCTION; RESPIRATORY TRACT INFLAMMATION; TISSUE CULTURE; UPREGULATION;

GENOTYPE; GLUTATHIONE TRANSFERASE; HETEROZYGOTE; HISTAMINE RELEASE; HUMANS; NASAL MUCOSA; OXIDOREDUCTASES; OZONE; POLYMORPHISM, GENETIC;

EID: 0037294454     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110300000     Document Type: Article

References (40)

1. McDonnell WF, Stewart PW, Smith MV, Pan WK, Pan J. Ozone-induced respiratory symptoms: exposure-response models and association with lung function. Eur Respir J 1999; 14: 845-53.
2. McDonnell WF, Stewart PW, Andreoni S, Seal E, Jr, Kehrl HR, Horstman DH et al. Prediction of ozone-induced FEV1 changes. Effects of concentration, duration, and ventilation. Am J Respir Crit Care Med 1997; 156: 715-22.
3. Mudway IS, Kelly FJ. Ozone and the lung: a sensitive issue. Mol Aspects Med 2000; 21: 1-48.
4. Kleeberger S. Genetic susceptibility to ozone exposure. Toxicol Lett 1995 82-83: 295-300.
5. Wesselkamper SC, Prows DR, Biswas P, Willeke K, Bingham E, Leikauf GD. Genetic susceptibility to irritant-induced acute lung injury in mice. Am J Physiol Lung Cell Mol Physiol 2000 Sep; 279: L575-82.
6. Kafoury RM, Pryor WA, Squadrito GL, Salgo MG, Zou X, Friedman M. Induction of inflammatory mediators in human airway epithelial cells by lipid ozonation products. Am J Respir Crit Care Med 1999; 160: 1934-42.
7. Dahlen SE, Hedqvist P, Hammarstrom S, Samuelsson B. Leukotrienes are potent constrictors of human bronchi. Nature 1980; 288: 484-6.
8. Schierhorn K, Zhang M, Kacy M, Kunkel G. Ozone-induced augmentation of eicosanoid metabolism in human nasal mucosa in vitro. Int Arch Allergy Immunol 1997; 113: 312-5.
9. Heffner JE, Repine JE. Pulmonary strategies of antioxidant defense. Am Rev Respir Dis 1989; 140: 531-54.
10. Rahman I, Clerch LB, Massaro D. Rat lung antioxidant enzyme induction by ozone. Am J Physiol 1991; 260: L412-8.
11. Hayes JD, Strange RC. Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology 2000 Sep; 61: 154-66.
12. Strange RC, Spiteri MA, Ramachandran S, Fryer AA. Glutathione-S-transferase family of enzymes. Mutat Res 2001 Oct 1; 482: 21-6.
13. Vos RM, Rietjens IM, Stevens LH, Van Bladeren PJ. Methyl linoleate ozonide as a substrate for rat glutathione S-transferases: reaction pathway and isoenzyme selectivity. Chem Biol Interact 1989; 69: 269-78.
14. Clapper ML. Genetic polymorphism and cancer risk. Curr Oncol Rep 2000; 2: 251-6.
15. Hoidal JR. Genetics of COPD: present and future. Eur Respir J 2001; 18: 741-3.
16. Nakajima T, Elovaara E, Anttila S, Hirvonen A, Camus AM, Hayes JD et al. Expression and polymorphism of glutathione S-transferase in human lungs: risk factors in smoking-related lung cancer. Carcinogenesis 1995; 16: 707-11.
17. Abbey DE, Nishino N, McDonnell WF, Burchette RJ, Knutsen SF, Lawrence Beeson W, Yang JX. Long-term inhalable particles and other air pollutants related to mortality in nonsmokers. Am J Respir Crit Care Med 1999; 159: 354-6.
18. Calderon-Garciduenas L, Valencia-Salazar G, Rodriguez-Alcaraz A, Gambling TM, Garcia R, Osnaya N et. al. Ultrastructural nasal pathology in children chronically and sequentially exposed to air pollutants. Am J Respir Cell Mol Biol 2001 Feb; 24: 132-8.
19. Calderon-Garciduenas L, Rodriguez-Alcaraz A, Valencia-Salazar G, Mora-Tascareno A, Garcia R, Osnaya N et. al. Nasal biopsies of children exposed to air pollutants. Toxicol Patho 2001 Sep-Oct; 29: 558-64.
20. Prows DR, Shertzer HG, Daly MJ, Sidman CL, Leikauf GD. Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice. Nat Genet 1997; 17: 471-4.
21. Schierhorn K, Brunnee T, Paus R, Schultz KD, Niehus J, Agha Mir Salim P et al. Gelatin sponge-supported histoculture of human nasal mucosa. In Vitro Cell Dev Biol Anim 1995; 31: 215-20.
22. Siraganian RP. An automated continuous-flow system for the extraction and fluorometric analysis of histamine. Anal Biochem 1974; 57: 383-94.
23. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD et al. Measurement of protein using bicinchoninic acid [published erratum appears in Anal Biochem 1987 May 15;163:279]. Anal Biochem 1985; 150: 76-85.
24. Beers RF, Sizer IW. J Biol Chem 1952; 195: 133-140.
25. Wendel A. Enzymatic Basis of of Detoxification. New York: Academic press, 1980: 333.
26. Mavis RD, Stellwagen E. Purification and Subunit Structure of Glutathione Reductase from Bakers' Yeast. J Biol Chem 1968; 243: 809-814.
27. Nebot C, Moutet M, Huet P, Xu JZ, Yadan JC, Chaudiere J. Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol. Anal Biochem 1993; 214: 442-51.
28. Pabst MJ, Habig WH, Jakoby WB. Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration. J Biol Chem 1974; 249: 7140-7.
29. McLellan RA, Oscarson M, Alexandrie AK, Seidegard J, Evans DA, Rannug A et al. Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity. Mol Pharmacol 1997; 52: 958-65.
30. Kleeberger SR, Kolbe J, Adkinson NF, Peters SP, Spannhake EW. The role of mediators in the response of the canine peripheral lung to 1 ppm ozone. Am Rev Respir Dis 1988; 137: 321-5.
31. Schierhorn K, Zhang M, Matthias C, Kunkel G. Influence of ozone and nitrogen dioxide on histamine and interleukin formation in a human nasal mucosa culture system. Am J Respir Cell Mol Biol 1999; 20: 1013-9.
32. Schierhorn K, Zhang M, Matthias C, Kunkel G. Ozone-induced release of histamine in human nasal mucosa of smokers and non-smokers in organ culture. Int Arch Allergy Immunol 1999 Feb-Apr; 118: 333-4.
33. Quinlan T, Spivack S, Mossman BT. Regulation of antioxidant enzymes in lung after oxidant injury. Environ Health Perspect 1994; 102 Suppl 2: 79-87.
34. Duan X, Buckpitt AR, Plopper CG. Variation in antioxidant enzyme activities in anatomic subcompartments within rat and rhesus monkey lung. Toxicol Appl Pharmacol 1993; 123: 73-82.
35. Plopper CG, Duan X, Buckpitt AR, Pinkerton KE. Dose-dependent tolerance to ozone. IV. Site-specific elevation in antioxidant enzymes in the lungs of rats exposed for 90 days or 20 months. Toxicol Appl Pharmacol 1994; 127: 124-31.
36. Mudway IS, Blomberg A, Frew AJ, Holgate ST, Sandstrom T, Kelly FJ. Antioxidant consumption and repletion kinetics in nasal lavage fluid following exposure of healthy human volunteers to ozone. Eur Respir J 1999 Jun; 13: 1429-38.
37. Warner BB, Stuart L, Gebb S, Wispe JR. Redox regulation of manganese superoxide dismutase. Am J Physiol 1996; 271: L150-8.
38. Visner GA, Dougall WC, Wilson JM, Burr IA, Nick HS. Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response. J Biol Chem 1990; 265: 2856-64.
39. Berhane K, Widersten M, Engstrom A, Kozarich JW, Mannervik B. Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc Natl Acad Sci USA 1994 Feb; 91: 1480-4.
40. Kleeberger SR, Levitt RC, Zhang LY, Longphre M, Harkema J, Jedlicka A et al. Linkage analysis of susceptibility to ozone-induced lung inflammation in inbred mice. Nat Genet 1997; 17: 475-8.