Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice

Nature Genetics

Volumn 17, Issue 4, 1997, Pages 471-474

  Prows, Daniel R ^a   Shertzer, Howard G ^a   Daly, Mark J ^b   Sidman, Charles L ^c   Leikauf, George D ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OZONE;

ACUTE DISEASE; AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; LUNG INJURY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SURVIVAL TIME;

ANIMALIA;

EID: 0030725492     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1297-471     Document Type: Article

References (30)

1. Ostro, B.D. The association of air pollution and mortality: examining the case for inference. Arch. Environ. Health 48, 335-342 (1993).
2. Pope, C.A., III, Dockery, D.W. & Schwartz, J. Review of epidemiological evidence of health effects of particulate air pollution. Inhalation Toxicology 7, 1-18 (1995).
3. Kehrer, J.P. Free radicals as mediators of tissue injury and disease. Crit. Rev. Toxicol. 23, 21-48 (1993).
4. Halliwell, B. & Cross, C.E. Oxygen-derived species: their relation to human disease and environmental stress. Environ. Health Perspect. 102 (Suppl. 10), 5-12 (1994).
5. Lippmann, M., Ozone, in Environmental Toxicants: Human Exposures and Their Health Effects (ed. Lippmann, M.) 465-519 (Van Nostrand Reinhold, New York, 1993).
6. Mustafa, M.G. Biochemical basis of ozone toxicity. Free Radical Biol. Med. 9, 245-265 (1990).
7. Silverman, F. Asthma and respiratory irritants (ozone). Environ. Health Perspect. 29, 131-136 (1979).
8. Lippmann, M. et al. Effects of ozone on the pulmonary function of children. Adv. Mod. Environ. Toxicol. 5, 423-446 (1983).
9. Spektor, D.M. et al. Effects of ambient ozone on respiratory function in healthy adults exercising outdoors. Am. Rev. Respir. Dis. 138, 821-828 (1988).
10. Kreit, J.W. et al. Ozone-induced changes in pulmonary function and responsiveness in asthmatics. J. Appl. Physiol. 66, 217-222 (1989).
11. McBride, D.E., Koenig, J.Q., Luchtel, D.L., Williams, P.V. & Henderson, W.R., Jr. Inflammatory effects of ozone in the upper airways of subjects with asthma. Am. Rev. Respir. Crit. Care Med. 149, 1192-1197 (1994).
12. McDonnell, W.F. Intersubject variability in human acute ozone responsiveness. Pharmacogenetics 1, 110-113 (1991).
13. Kleeberger, S.R., Bassett, D.J.P., Jakab, G.J. & Levitt, R.C. A genetic model for evaluation of susceptibility to ozone-induced inflammation. Am. J. Physiol. 258, L313-L320 (1990).
14. Kleeberger, S.R., Levitt, R.C. & Zhang, L.-Y. Susceptibility to ozone-induced inflammation. I. Genetic control of the response to subacute exposure. Am. J. Physiol. 264, L15-L20 (1993).
15. Stokinger, H.E. Evaluation of the hazards of ozone and oxides of nitrogen: factors modifying toxicity. Arch. Ind. Health 15, 181-190 (1957).
16. Goldstein, B.D., Lai, L.Y., Ross, S.R. & Cuzzi-Spada, R. Susceptibility of inbred mouse strains to ozone. Arch. Environ. Health 27, 412-413 (1973).
17. Taylor, B. A. in Origins of Inbred Mice (ed. Morse, H.C., III) 423-438 (Academic, New York, 1978).
18. Manly, K.F. & Elliott, R.W. RI Manager, a microcomputer program for analysis of data from recombinant inbred strains. Mamm. Genome 1, 123-126 (1991).
19. Nesbitt, M.N. & Skamene, E. Recombinant inbred mouse strains derived from the A/J and C57BL/6J: a tool for the study of genetic mechanisms in host resistance to infection and malignancy. J. Leukocyte Biol. 36, 357-364 (1984).
20. Marshall, J.D. et al. The AXB and BXA set of recombinant inbred mouse strains. Mamm. Genome 3, 669-680 (1992).
21. DeSanctis, G.T. et al. Quantitative locus analysis of airway hyperresponsiveness in A/J and C56BL/6J mice. Nature Genet. 11, 150-154 (1995).
22. Lincoln, S.E., Daly, M.J. & Lander, E.S. Mapping Genes Controlling Quantitative Traits with MAPMAKER/EXP 1.1, 2nd ed. (Whitehead Institute Technical Report, Cambridge, Massachusetts, 1992).
23. Paterson, A.M. et al. Mendelian factors underlying quantitative traits in tomato: comparison across species, generations, and environments. Genetics 127, 181-197 (1991).
24. Lander, E. & Kruglyak, L. Genetic dissection of complex traits: guidelines for interpreting and reporting results. Nature Genet. 11, 241-247 (1995).
25. Cattanach, B.M. & Jones, J. Genetic imprinting in the mouse: implications for gene regulation. J. Inherited Metab. Dis. 17, 403-420 (1994).
26. Sapienza, C., Paquette, J., Pannunzio, P., Albrechtson, A. & Morgan, K. The polarlethal ovum mutant gene maps to the distal portion of mouse chromosome 17. Genetics 132, 241-246 (1992).
27. Copeland, N.G. et al. Genome maps IV: The mouse. Science 262, 67-82 (1993).
28. Special report. Mamm. Genome 6, S1-S352 (1996).
29. Peden, D.B. et al. Uric acid is a major antioxidant in human nasal airway secretions. Proc. Natl. Acad. Sci. USA 87, 7638-7642 (1990).
30. Cross, C.E., van der Vliet, A., O'Neill, C.A., Louie, S. & Halliwell, B. Oxidants, antioxidants, and respiratory tract lining fluids. Environ. Health Perspect. 102 (Suppl. 10), 185-191 (1994).