I. Of mice and men (and rats): Implications of species and stimulus differences for the interpretation of studies of nitric oxide in sepsis

British Journal of Anaesthesia

Volumn 90, Issue 2, 2003, Pages 115-118

  Reade, M C ^a   Young, J D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CARBON MONOXIDE; CYTOKINE; ENDOTOXIN; FREE RADICAL; HEME OXYGENASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; NOS2 PROTEIN, RAT; NOS2A PROTEIN, HUMAN; VASODILATOR AGENT;

CELL CULTURE; CLINICAL STUDY; DISEASE MODEL; DOG; EDITORIAL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; INFLAMMATION; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MEDICAL LITERATURE; MONONUCLEAR CELL; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SEPTIC SHOCK; SMOOTH MUSCLE FIBER; SPECIES DIFFERENCE; STIMULUS RESPONSE; SWINE; VASCULAR SMOOTH MUSCLE; VASODILATATION; ANIMAL; BIOSYNTHESIS; METABOLISM; SEPSIS;

ANIMALS; ARGININE; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; DOGS; HEME OXYGENASE (DECYCLIZING); HUMANS; MICE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; SEPSIS; SHOCK, SEPTIC; SPECIES SPECIFICITY; SWINE; VASODILATOR AGENTS;

EID: 0037289751     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeg033     Document Type: Editorial

References (40)

1. Spitzer J. Animal models of endotoxaemia and sepsis. In: Schlag G, Redl H, eds. Pathophysiology of Shock, Sepsis and Organ Failure. Berlin: Springer-Verlag, 1993
2. Lander HM, Sehajpal P, Levine DM, Novogrodsky A. Activation of human peripheral blood mononuclear cells by nitric oxide generating compounds. J Immunol 1993; 150: 1509-16
3. Titheradge MA. Nitric oxide in septic shock. Biochim Biophys Acta 1999; 1411: 437-55
4. MacKenzie IM, Garrard CS, Young JD. Indices of nitric oxide synthesis and outcome in critically ill patients. Anaesthesia 2001; 56: 326-30
5. Evans T, Carpenter A, Kinderman H, Cohen J. Evidence of increased nitric oxide production in patients with the sepsis syndrome. Circ Shock 1993; 41: 77-81
6. Groeneveld PH, Kwappenberg KM, Langermans JA, Nibbering PH, Curtis L. Nitric oxide (NO) production correlates with renal insufficiency and multiple organ dysfunction syndrome in severe sepsis. Intensive Care Med 1996; 22: 1197-202
7. Krafte-Jacobs B, Brilli R, Szabo C, Denenberg A, Moore L, Salzman AL. Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock. Crit Care Med 1997; 25: 1588-93
8. Sakemi K, Ohno Y, Tsuda M. NO2-/NO3-levels in blood and principal organs in rats treated with lipopolysaccharide. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku 1998; 116: 101-6
9. Harbrecht BG, Di Silvio M, Demetris AJ, Simmons RL, Billiar TR. Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia. Hepatology 1994; 20: 1055-60
10. Sakurai H, Kohsaka H, Liu MF, et al. Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides. J Clin Invest 1995; 96: 2357-63
11. Godkin AJ, De Belder AJ, Villa L, et al. Expression of nitric oxide synthase in ulcerative colitis. Eur J Clin Invest 1996; 26: 867-72
12. Chesrown SE, Monnier J, Visner G, Nick HS. Regulation of inducible nitric oxide synthase mRNA levels by LPS, INF-gamma, TGF-beta, and IL-10 in murine macrophage cell lines and rat peritoneal macrophages. Biochem Biophys Res Commun 1994; 200: 126-34
13. Caivano M. Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages. FEBS Lett 1998; 429: 249-53
14. Schneemann M, Schoedon G, Hofer S, Blau N, Guerrero L, Schaffner A. Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J Infect Dis 1993; 167: 1358-63
15. Weinberg JB, Misukonis MA, Shami PJ, et al. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. Blood 1995; 86: 1184-95
16. Reade MC, Clark MF, Young JD, Boyd CAR. Increased cationic amino acid flux through a newly expressed transporter in cells overproducing nitric oxide from patients with septic shock. Clin Sci (Lond) 2002; 102: 645-50
17. Gill DJ, Low BC, Grigor MR. Interleukin-I beta and tumor necrosis factor-alpha stimulate the CAT2 gene of the L-arginine transporter in cultured vascular smooth muscle cells. J Biol Chem 1996; 271: 11280-3
18. Julou-Schaeffer G, Gray GA, Fleming I, Schott C, Parratt JR, Stoclet JC. Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am J Physiol 1990; 259: H1038-43
19. Vromen A, Arkovitz MS, Zingarelli B, Salzman AL, Garcia VF, Szabo C. Low-level expression and limited role for the inducible isoform of nitric oxide synthase in the vascular hyporeactivity and mortality associated with cecal ligation and puncture in the rat. Shock 1996; 6: 248-53
20. MacNaul KL, Hutchinson NI. Differential expression of iNOS and cNOS mRNA in human vascular smooth muscle cells and endothelial cells under normal and inflammatory conditions. Biochem Biophys Res Commun 1993; 196: 1330-4
21. Chester AH, Borland JA, Buttery LD, et al. Induction of nitric oxide synthase in human vascular smooth muscle: interactions between proinflammatory cytokines. Cardiovasc Res 1998; 38: 814-21
22. Bhagat K, Hingorani AD, Palacios M, Charles IG, Vallance P. Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. Cardiovasc Res 1999; 41: 754-64
23. Bhagat K, Collier J, Vallance P. Local venous responses to endotoxin in humans. Circulation 1996; 94: 490-7
24. Stoclet JC, Martinez MC, Ohlmann P, et al. Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock. Circulation 1999; 100: 107-12
25. Tsuneyoshi I, Kanmura Y, Yoshimura N. Nitric oxide as a mediator of reduced arterial responsiveness in septic patients. Crit Care Med 1996; 24: 1083-6
26. Petros A, Lamb G, Leone A, Moncada S, Bennett D, Vallance P. Effects of a nitric oxide synthase inhibitor in humans with septic shock. Cardiovasc Res 1994; 28: 34-9
27. Closs EI, Scheld JS, Sharafi M, Forstermann U. Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters. Mol Pharmacol 2000; 57: 68-74
28. Hishikawa K, Nakaki T, Tsuda M, et al. Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man. Jpn Heart J 1992; 33: 41-8
29. Xia Y, Zweier JL. Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proc Natl Acad Sci USA 1997; 94: 6954-8
30. Hammermann R, Dreissig MD, Mossner J, et al. Nuclear factor-kappa B mediates simultaneous induction of inducible nitric oxide synthase and Up-regulation of the cationic amino acid transporter CAT-2B in rat alveolar macrophages. Mol Pharmacol 2000; 58: 1294-302
31. Irie K, Tsukahara F, Fujii E, et al. Cationic amino acid transporter-2 mRNA induction by tumor necrosis factor-alpha in vascular endothelial cells. Eur J Pharmacol 1997; 339: 289-93
32. + correlates with expression of the T-cell early antigen gene in human lymphocytes. Pflügers Arch 1992; 422: 87-9
33. Durante W, Liao L, Schafer AI. Differential regulation of L-arginine transport and inducible NOS in cultured vascular smooth muscle cells. Am J Physiol 1995; 268: H1158-64
34. + and cationic amino acid transporter gene expression in cultured vascular smooth muscle cells. J Biol Chem 1995; 270: 27577-83
35. Kakuda DK, Finley KD, Maruyama M, MacLeod CL. Stress differentially induces cationic amino acid transporter gene expression. Biochim Biophys Acta 1998; 1414: 75-84
36. Buga GM, Griscavage JM, Rogers NE, Ignarro LJ. Negative feedback regulation of endothelial cell function by nitric oxide. Circ Res 1993; 73: 808-12
37. Camhi SL, Alam J, Otterbein L, Sylvester SL, Choi AM. Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. Am J Respir Cell Mol Biol 1995; 13: 387-98
38. Scharte M, Bone HG, Van Aken H, Meyer J. Increased carbon monoxide in exhaled air of critically ill patients. Biochem Biophys Res Commun 2000; 267: 423-6
39. Shi Y, Pan F, Li H, et al. Plasma carbon monoxide levels in term newborn infants with sepsis. Biol Neonate 2000; 78: 230-2
40. Hartsfield CL. Cross talk between carbon monoxide and nitric oxide. Antioxid Redox Signal 2002; 4: 301-7