M1 receptor-mediated nitric oxide-dependent relaxation unmasked in stomach fundus from M3 receptor knockout mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 304, Issue 2, 2003, Pages 675-682

  Stengel, Peter W ^a   Cohen, Marlene L ^a,b  

^a ELI LILLY AND COMPANY   (United States)

^b Creative Pharmacology Solutions LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[4 [(3 CHLOROPHENYL)CARBAMOYLOXY] 2 BUTYNYL]TRIMETHYLAMMONIUM; CARBACHOL; INDOMETACIN; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M1 RECEPTOR ANTAGONIST; MUSCARINIC M3 RECEPTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PIRENZEPINE; PROSTAGLANDIN SYNTHASE INHIBITOR; TETRODOTOXIN; MUSCARINIC RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL ACTIVATION; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ELECTRIC FIELD; KNOCKOUT MOUSE; MOUSE; MUSCLE RELAXATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SMOOTH MUSCLE CONTRACTILITY; STOMACH EMPTYING; STOMACH FUNDUS; WILD TYPE; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ELECTROSTIMULATION; GENETICS; IN VITRO STUDY; MALE; METHODOLOGY; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; GASTRIC FUNDUS; MALE; MICE; MICE, KNOCKOUT; MUSCARINIC AGONISTS; MUSCLE RELAXATION; NITRIC OXIDE; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M3; RECEPTORS, MUSCARINIC;

EID: 0037289733     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.042283     Document Type: Article

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