-
1
-
-
0023191072
-
Identification of a family of muscarinic acetylcholine receptor genes
-
Bonner, T.I., N.J. Buckley, A.C. Young and M.R. Brann, 1987, Identification of a family of muscarinic acetylcholine receptor genes, Science 237, 527.
-
(1987)
Science
, vol.237
, pp. 527
-
-
Bonner, T.I.1
Buckley, N.J.2
Young, A.C.3
Brann, M.R.4
-
2
-
-
0024039146
-
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
-
Bonner, T.I., A.C. Young, M.R. Brann and N.J. Buckley, 1988, Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes, Neuron 1, 403.
-
(1988)
Neuron
, vol.1
, pp. 403
-
-
Bonner, T.I.1
Young, A.C.2
Brann, M.R.3
Buckley, N.J.4
-
3
-
-
0039410502
-
Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): High throughput assays in mammalian cells
-
Bräuner-Osborne, H. and M.R. Brann, 1996, Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells, Eur. J. Pharmacol. 295, 93.
-
(1996)
Eur. J. Pharmacol.
, vol.295
, pp. 93
-
-
Bräuner-Osborne, H.1
Brann, M.R.2
-
4
-
-
0029062154
-
Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors
-
Bräuner-Osborne, H., B. Ebert, M.R. Brann, E. Falch and P. Krogsgaard-Larsen, 1995, Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors, J. Med. Chem. 38, 2188.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 2188
-
-
Bräuner-Osborne, H.1
Ebert, B.2
Brann, M.R.3
Falch, E.4
Krogsgaard-Larsen, P.5
-
5
-
-
0028957219
-
Constitutive activation of muscarinic receptors by the G protein Gq
-
Burstein, E.S., T.A. Spalding, H. Bräuner-Osborne and M.R. Brann, 1995, Constitutive activation of muscarinic receptors by the G protein Gq, FEBS Lett. 363, 261.
-
(1995)
FEBS Lett.
, vol.363
, pp. 261
-
-
Burstein, E.S.1
Spalding, T.A.2
Bräuner-Osborne, H.3
Brann, M.R.4
-
6
-
-
0024849550
-
Excitatory amino acid agonists and partial agonists
-
Christensen, I.T., A. Reinhardt, B. Nielsen, B. Ebert, E.Ø. Nielsen and P. Krogsgaard-Larsen, 1989, Excitatory amino acid agonists and partial agonists, Drug Des. Del. 5, 57.
-
(1989)
Drug Des. Del.
, vol.5
, pp. 57
-
-
Christensen, I.T.1
Reinhardt, A.2
Nielsen, B.3
Ebert, B.4
Nielsen, E.Ø.5
Krogsgaard-Larsen, P.6
-
7
-
-
0027245830
-
Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha
-
Conklin, B.R., Z. Farfel, K.D. Lustig, D. Julius and H.R. Bourne, 1993, Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha, Nature (London) 363, 274.
-
(1993)
Nature (London)
, vol.363
, pp. 274
-
-
Conklin, B.R.1
Farfel, Z.2
Lustig, K.D.3
Julius, D.4
Bourne, H.R.5
-
8
-
-
0028202566
-
Resolution, absolute stereochemistry, and pharmacology of the S-(+)-and R-(-)-isomers of the apparant partial AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R,S)-APPA]
-
Ebert, B., S. Lenz, L. Brehm, P. Bregnedal, J.J. Hansen, K. Frederiksen, K.P. Bøgesø and P. Krogsgaard-Larsen, 1994a, Resolution, absolute stereochemistry, and pharmacology of the S-(+)-and R-(-)-isomers of the apparant partial AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R,S)-APPA], J. Med. Chem. 37, 878.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 878
-
-
Ebert, B.1
Lenz, S.2
Brehm, L.3
Bregnedal, P.4
Hansen, J.J.5
Frederiksen, K.6
Bøgesø, K.P.7
Krogsgaard-Larsen, P.8
-
9
-
-
0028272399
-
Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazoyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA
-
Ebert, B., U. Madsen, T.M. Lund, S.M. Lenz and P. Krogsgaard-Larsen, 1994b, Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazoyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA, Neurochem. Int. 24, 507.
-
(1994)
Neurochem. Int.
, vol.24
, pp. 507
-
-
Ebert, B.1
Madsen, U.2
Lund, T.M.3
Lenz, S.M.4
Krogsgaard-Larsen, P.5
-
10
-
-
0001017033
-
Glutamic acid receptors in schizophrenia and Alzheimer's disease: Functional partial agonism and receptor modulation as potential therapeutic approaches
-
eds. R. Fog, J. Gerlach and R. Hemmingsen (Munksgaard, Copenhagen)
-
Ebert, B., K.K. Søby, U. Madsen and P. Krogsgaard-Larsen, 1995, Glutamic acid receptors in schizophrenia and Alzheimer's disease: functional partial agonism and receptor modulation as potential therapeutic approaches, in: Schizophrenia, Alfred Benzon Symposium 38, eds. R. Fog, J. Gerlach and R. Hemmingsen (Munksgaard, Copenhagen) p. 379.
-
(1995)
Schizophrenia, Alfred Benzon Symposium
, vol.38
, pp. 379
-
-
Ebert, B.1
Søby, K.K.2
Madsen, U.3
Krogsgaard-Larsen, P.4
-
11
-
-
85030270501
-
Functional partial agonism as demonstrated for ionotropic glutamate receptors
-
in press
-
Ebert, B., U. Madsen, K.K. Søby and P. Krogsgaard-Larsen, 1996, Functional partial agonism as demonstrated for ionotropic glutamate receptors, Neurochem. Int. (in press).
-
(1996)
Neurochem. Int.
-
-
Ebert, B.1
Madsen, U.2
Søby, K.K.3
Krogsgaard-Larsen, P.4
-
12
-
-
0028318880
-
New insights into receptor theory, as provided by an artificial partial agonist made-to-measure
-
Feuerstein, T.J., W. Sauermann, C. Allgaier, E. Agneter and E.A. Singer, 1994, New insights into receptor theory, as provided by an artificial partial agonist made-to-measure, Naunyn-Schmiedeberg's Arch. Pharmacol. 350, 1.
-
(1994)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.350
, pp. 1
-
-
Feuerstein, T.J.1
Sauermann, W.2
Allgaier, C.3
Agneter, E.4
Singer, E.A.5
-
13
-
-
0025855010
-
Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes
-
Gutkind, J.S., E.A. Novotny, M.R. Brann and K.C. Robbins, 1991, Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes, Proc. Natl. Acad. Sci. USA 88, 4703.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4703
-
-
Gutkind, J.S.1
Novotny, E.A.2
Brann, M.R.3
Robbins, K.C.4
-
14
-
-
0025856977
-
Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells
-
Hu, J., S.Z. Wang and E.E. El-fakahany, 1991, Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells, J. Pharmacol. Exp. Ther. 257, 938.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.257
, pp. 938
-
-
Hu, J.1
Wang, S.Z.2
El-Fakahany, E.E.3
-
15
-
-
0024600440
-
Theoretical effects of single and multiple transducer receptor coupling proteins on estimates of the relative potency of agonists
-
Kenakin, T.P. and P.H. Morgan, 1989, Theoretical effects of single and multiple transducer receptor coupling proteins on estimates of the relative potency of agonists, Mol. Pharmacol. 35, 214.
-
(1989)
Mol. Pharmacol.
, vol.35
, pp. 214
-
-
Kenakin, T.P.1
Morgan, P.H.2
-
16
-
-
0024410405
-
A simple assay for DNA transfection by incubation of the cells in culture dishes with substrates for beta-galactosidase
-
Lim, K. and C.-B. Chae, 1989, A simple assay for DNA transfection by incubation of the cells in culture dishes with substrates for beta-galactosidase, BioTechniques 7, 576.
-
(1989)
BioTechniques
, vol.7
, pp. 576
-
-
Lim, K.1
Chae, C.-B.2
-
17
-
-
0028986883
-
High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells
-
Messier, T.L., C.M. Dorman, H. Bräuner-Osborne, D. Eubanks and M.R. Brann, 1995, High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells, Pharmacol. Toxicol. 76, 308.
-
(1995)
Pharmacol. Toxicol.
, vol.76
, pp. 308
-
-
Messier, T.L.1
Dorman, C.M.2
Bräuner-Osborne, H.3
Eubanks, D.4
Brann, M.R.5
-
18
-
-
0025362575
-
Desensitization of muscarinic stimulated hippocampal cell firing is related to phosphoinositide hydrolysis and inhibited by lithium
-
Pontzer, N.J. and F.T. Crews, 1990, Desensitization of muscarinic stimulated hippocampal cell firing is related to phosphoinositide hydrolysis and inhibited by lithium, J. Pharmacol. Exp. Ther. 253, 921.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.253
, pp. 921
-
-
Pontzer, N.J.1
Crews, F.T.2
-
19
-
-
0025276081
-
Relationship between agonist-induced muscarinic receptor loss and desensitization of stimulated phosphoinositide turnover in two neuroblastomas: Methodological considerations
-
Thompson, A.K. and S.K. Fisher, 1990, Relationship between agonist-induced muscarinic receptor loss and desensitization of stimulated phosphoinositide turnover in two neuroblastomas: methodological considerations, J. Pharmacol. Exp. Ther. 252, 744.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 744
-
-
Thompson, A.K.1
Fisher, S.K.2
-
20
-
-
0000921501
-
Analysis of dose-response curves
-
eds. E.E. Daniel and D.M. Paton (Plenum, New York)
-
Waud, D.R., 1975, Analysis of dose-response curves, in: Methods in Pharmacology, Vol. 3, eds. E.E. Daniel and D.M. Paton (Plenum, New York) p. 471.
-
(1975)
Methods in Pharmacology
, vol.3
, pp. 471
-
-
Waud, D.R.1
-
22
-
-
0017647917
-
Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells
-
Wigler, M., S. Silverstein, L.-S. Lee, A. Pellicer, Y.-C. Cheng and R. Axel, 1977, Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells, Cell 11, 223.
-
(1977)
Cell
, vol.11
, pp. 223
-
-
Wigler, M.1
Silverstein, S.2
Lee, L.-S.3
Pellicer, A.4
Cheng, Y.-C.5
Axel, R.6
-
23
-
-
0000803894
-
Drug receptors
-
Principles and Practice, ed. M.E. Wolff (John Wiley & Sons, New York)
-
Williams, M., D.C. Deecher and J.P. Sullivan, 1995, Drug receptors, in: Burger's Medicinal Chemistry and Drug Discovery, Vol. 1: Principles and Practice, ed. M.E. Wolff (John Wiley & Sons, New York) p. 349.
-
(1995)
Burger's Medicinal Chemistry and Drug Discovery
, vol.1
, pp. 349
-
-
Williams, M.1
Deecher, D.C.2
Sullivan, J.P.3
-
24
-
-
0027529259
-
Desensitization and reactivation of ACh-regulated exocrine secretion in hen tracheal epithelium
-
Winding, B. and N. Bindslev, 1993, Desensitization and reactivation of ACh-regulated exocrine secretion in hen tracheal epithelium, Am. J. Physiol. 264, C342.
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Winding, B.1
Bindslev, N.2
|