메뉴 건너뛰기




Volumn 138, Issue 1, 2003, Pages 245-253

5-Hydroxyindole causes convulsions and increases transmitter release in the CA1 region of the rat hippocampus

Author keywords

5 hydroxyindole; CA1; GABA; Glutamate; Hepatic encephalopathy; NAChR; Synaptic transmission

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 5 HYDROXYINDOLE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; N METHYL DEXTRO ASPARTIC ACID; TETRODOTOXIN; TROPISETRON;

EID: 0037278486     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705007     Document Type: Article
Times cited : (15)

References (42)
  • 1
    • 0033619660 scopus 로고    scopus 로고
    • Hepatic encephalopathy: Molecular mechanisms underlying the clinical syndrome
    • ALBRECHT, J. & JONES, E.A. (1999). Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome. J. Neurol. Sci., 170, 138-146.
    • (1999) J. Neurol. Sci. , vol.170 , pp. 138-146
    • Albrecht, J.1    Jones, E.A.2
  • 2
    • 0031443680 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices
    • ALKONDON, M., PEREIRA, E.F., BARBOSA, C.T. & ALBUQUERQUE, E.X. (1997). Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices. J. Pharmacol. Exp. Ther., 283, 1396-1411.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 1396-1411
    • Alkondon, M.1    Pereira, E.F.2    Barbosa, C.T.3    Albuquerque, E.X.4
  • 3
    • 0004686730 scopus 로고    scopus 로고
    • Plasma and brain levels of oxindole in experimental chronic hepatic encephalopathy: Effects of systemic ammonium acetate and L-tryptophan
    • BERQVIST, P.B.F., CARPENEDO, R., APELQVISI, G., MORONI, F. & BENGTSSON, F. (1999). Plasma and brain levels of oxindole in experimental chronic hepatic encephalopathy: effects of systemic ammonium acetate and L-tryptophan. Pharmacol. Toxicol., 85, 138-143.
    • (1999) Pharmacol. Toxicol. , vol.85 , pp. 138-143
    • Berqvist, P.B.F.1    Carpenedo, R.2    Apelqvisi, G.3    Moroni, F.4    Bengtsson, F.5
  • 4
    • 0031739382 scopus 로고    scopus 로고
    • Net interaction between different forms of short-term synaptic plasticity and slow-IPSPs in the hippocampus and auditory cortex
    • BUONOMANO, D.V. & MERZENICH, M.M. (1998). Net interaction between different forms of short-term synaptic plasticity and slow-IPSPs in the hippocampus and auditory cortex. J. Neurophysiol., 80, 1765-1774.
    • (1998) J. Neurophysiol. , vol.80 , pp. 1765-1774
    • Buonomano, D.V.1    Merzenich, M.M.2
  • 5
    • 0035173678 scopus 로고    scopus 로고
    • Neurotransmitter dysfunction in hepatic encephalopathy: New approaches and new findings
    • BUTTERWORTH, R.F. (2001). Neurotransmitter dysfunction in hepatic encephalopathy: new approaches and new findings. Metab. Brain Dis., 16, 55-65.
    • (2001) Metab. Brain Dis. , vol.16 , pp. 55-65
    • Butterworth, R.F.1
  • 6
    • 0031014989 scopus 로고    scopus 로고
    • Identification and measurement of oxindole (2-indolinone) in the mammalian brain and other rat organs
    • CARPENEDO, R., CARLÀ, V., MONETI, G., CHIARUGI, A. & MORONI, F. (1997). Identification and measurement of oxindole (2-indolinone) in the mammalian brain and other rat organs. Analyt. Biochem., 244, 74-79.
    • (1997) Analyt. Biochem. , vol.244 , pp. 74-79
    • Carpenedo, R.1    Carlà, V.2    Moneti, G.3    Chiarugi, A.4    Moroni, F.5
  • 7
    • 0028305047 scopus 로고
    • Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenic acid and have sedative and anticonvulsant activities
    • CARPENEDO, R., CHIARUGI, A., RUSSI, P., LOMBARDI, G., CARLÀ, V., PELLICCIARI, R., MATTOLI, L. & MORONI, F. (1994). Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenic acid and have sedative and anticonvulsant activities. Neuroscience, 61, 237-244.
    • (1994) Neuroscience , vol.61 , pp. 237-244
    • Carpenedo, R.1    Chiarugi, A.2    Russi, P.3    Lombardi, G.4    Carlà, V.5    Pellicciari, R.6    Mattoli, L.7    Moroni, F.8
  • 8
    • 0031978616 scopus 로고    scopus 로고
    • Oxindole, a sedative tryptophan metabolite, accumulates in blood and brain of rats with acute hepatic failure
    • CARPENEDO, R., MANNAIONI, G. & MORONI, F. (1998). Oxindole, a sedative tryptophan metabolite, accumulates in blood and brain of rats with acute hepatic failure. J. Neurochem., 70, 1998-2003.
    • (1998) J. Neurochem. , vol.70 , pp. 1998-2003
    • Carpenedo, R.1    Mannaioni, G.2    Moroni, F.3
  • 9
    • 0020647470 scopus 로고
    • Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus
    • COLLINGRIDGE, G.L., KEHL, S.J. & McLENNAN, H. (1983). Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. J. Physiol., 334, 33-46.
    • (1983) J. Physiol. , vol.334 , pp. 33-46
    • Collingridge, G.L.1    Kehl, S.J.2    McLennan, H.3
  • 10
    • 0030873754 scopus 로고    scopus 로고
    • Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: In vivo studies with (2S, 1′S, 2′S, 3′R)-2-(2′-carboxy-3′-phenylcyclopropyl)glycine, a new potent and selective antagonist
    • COZZI, A., ATTUCCI, S., PERUGINELLI, F., MARINOZZI, M., LUNEIA, R., PELLICCIARI, R. & MORONI, F. (1997). Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S, 1′S, 2′S, 3′R)-2-(2′-carboxy-3′-phenylcyclopropyl)glycine, a new potent and selective antagonist. Eur. J. Neurosci., 9, 1350-1355.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1350-1355
    • Cozzi, A.1    Attucci, S.2    Peruginelli, F.3    Marinozzi, M.4    Luneia, R.5    Pellicciari, R.6    Moroni, F.7
  • 12
    • 0032105338 scopus 로고    scopus 로고
    • Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons
    • FISHER, J.L., PIDOPLICHKO, V.I. & DANI, J.A. (1998). Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons. J. Physiol. (Paris), 92, 209-213.
    • (1998) J. Physiol. (Paris) , vol.92 , pp. 209-213
    • Fisher, J.L.1    Pidoplichko, V.I.2    Dani, J.A.3
  • 13
    • 0025318104 scopus 로고
    • Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands
    • GAMMAL, S.H., BASILE, A.S., GELLER, D., SKOLNICK, P. & JONES, E.A. (1990). Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands. Hepatology, 11, 371-378.
    • (1990) Hepatology , vol.11 , pp. 371-378
    • Gammal, S.H.1    Basile, A.S.2    Geller, D.3    Skolnick, P.4    Jones, E.A.5
  • 15
    • 0022005967 scopus 로고
    • Quantitative studies of some antagonists of NMDA in slices of rat cerebral cortex
    • HARRISON, N.L & SIMMONDS, M.A. (1985). Quantitative studies of some antagonists of NMDA in slices of rat cerebral cortex. Br. J. Pharmacol., 84, 381-391.
    • (1985) Br. J. Pharmacol. , vol.84 , pp. 381-391
    • Harrison, N.L.1    Simmonds, M.A.2
  • 16
    • 0013863636 scopus 로고
    • The metabolism of [2-14C] indole in the rat
    • KING, L.J., PARKE, D.V. & WILLIAMS, R.T. (1966). The metabolism of [2-14C] indole in the rat. Biochem. J., 98, 266-277.
    • (1966) Biochem. J. , vol.98 , pp. 266-277
    • King, L.J.1    Parke, D.V.2    Williams, R.T.3
  • 17
    • 0028234863 scopus 로고
    • Competitive and non-competitive effects of 5-hydroxyindole on 5-HT3 receptors in N1E-115 neuroblastoma cells
    • KOOYMAN, A.R., VAN HOOFT, J.A., VANDERHEIJDEN, P.M. & VIJVERBERG, H.P. (1994). Competitive and non-competitive effects of 5-hydroxyindole on 5-HT3 receptors in N1E-115 neuroblastoma cells. Br. J. Pharmacol., 112, 541-546.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 541-546
    • Kooyman, A.R.1    Van Hooft, J.A.2    Vanderheijden, P.M.3    Vijverberg, H.P.4
  • 18
    • 0027530776 scopus 로고
    • 5-Hydroxyindole slows desensitization of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells
    • KOOYMAN, A.R., VAN HOOFT, J.A. & VIJVERBERG, H.P. (1993). 5-Hydroxyindole slows desensitization of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells. Br. J. Pharmacol., 108, 287-289.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 287-289
    • Kooyman, A.R.1    Van Hooft, J.A.2    Vijverberg, H.P.3
  • 19
    • 0027213356 scopus 로고
    • Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus
    • LENA, C., CHANGEUX, J.P. & MULLE, C. (1993). Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus. J. Neurosci., 13, 2680-2688.
    • (1993) J. Neurosci. , vol.13 , pp. 2680-2688
    • Lena, C.1    Changeux, J.P.2    Mulle, C.3
  • 20
    • 0018881875 scopus 로고
    • The use of in vitro brain slices for multidisciplinary studies of synaptic function
    • LYNCH, G. & SCHUBERT, P. (1980). The use of in vitro brain slices for multidisciplinary studies of synaptic function. Annu. Rev. Neurosci., 3, 1-22.
    • (1980) Annu. Rev. Neurosci. , vol.3 , pp. 1-22
    • Lynch, G.1    Schubert, P.2
  • 21
    • 0034177736 scopus 로고    scopus 로고
    • Cell surface domain specific postsynaptic currents evoked by identified GABAergic neurones in rat hippocampus in vitro
    • MACCAFERRI, G., ROBERTS, J.D., SZUCS, P., COTTINGHAM, C.A. & SOMOGYI, P. (2000). Cell surface domain specific postsynaptic currents evoked by identified GABAergic neurones in rat hippocampus in vitro. J. Physiol., 524, 91-116.
    • (2000) J. Physiol. , vol.524 , pp. 91-116
    • Maccaferri, G.1    Roberts, J.D.2    Szucs, P.3    Cottingham, C.A.4    Somogyi, P.5
  • 23
    • 0029902658 scopus 로고    scopus 로고
    • Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations
    • MANNAIONI, G., CARLÀ, V. & MORONI, F. (1996). Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations. Br. J. Pharmacol., 118, 1530-1536.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1530-1536
    • Mannaioni, G.1    Carlà, V.2    Moroni, F.3
  • 25
    • 0032406147 scopus 로고    scopus 로고
    • Electrophysiological studies on oxindole, a neurodepressant tryptophan metabolite
    • MANNAIONI, G., CARPENEDO, R., PUGLIESE, A.M., CORRADETTI, R. & MORONI, F. (1998). Electrophysiological studies on oxindole, a neurodepressant tryptophan metabolite. Br. J. Pharmacol., 125, 1751-1760.
    • (1998) Br. J. Pharmacol. , vol.125 , pp. 1751-1760
    • Mannaioni, G.1    Carpenedo, R.2    Pugliese, A.M.3    Corradetti, R.4    Moroni, F.5
  • 26
    • 0037075602 scopus 로고    scopus 로고
    • Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
    • MANSVELDER, H.D., KEATH, J.R. & MCGEHEE, D.S. (2002). Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron, 33, 905-919.
    • (2002) Neuron , vol.33 , pp. 905-919
    • Mansvelder, H.D.1    Keath, J.R.2    Mcgehee, D.S.3
  • 27
    • 0030833287 scopus 로고    scopus 로고
    • Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: Are they involved in hepatic encephalopathy?
    • eds. Felipo, V. & Grisolia, S. New York: Plenum Press
    • MORONI, F., CARPENEDO, R., MANNAIONI, G., GALLI, A., CHIARUGI, A., CARLÀ, V. & MONETI, G. (1997). Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? In Advances in Cirrhosis, Hyperammoniemia, and Hepatic Encephalopathy. eds. Felipo, V. & Grisolia, S. pp. 57-73. New York: Plenum Press.
    • (1997) Advances in Cirrhosis, Hyperammoniemia, and Hepatic Encephalopathy , pp. 57-73
    • Moroni, F.1    Carpenedo, R.2    Mannaioni, G.3    Galli, A.4    Chiarugi, A.5    Carlà, V.6    Moneti, G.7
  • 29
    • 0020681435 scopus 로고
    • The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy
    • MORONI, F., LOMBARDI, G., MONETI, G. & CORTESINI, C. (1983). The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy. J. Neurochem., 40, 850-854.
    • (1983) J. Neurochem. , vol.40 , pp. 850-854
    • Moroni, F.1    Lombardi, G.2    Moneti, G.3    Cortesini, C.4
  • 30
    • 0020002163 scopus 로고
    • In vitro changes in gamma-aminobutyric acid output from the cerebral cortex induced by inhibitors of gamma-aminobutyric acid uptake and metabolism
    • MORONI, F., MULAS, A., MONETI, G. & PEPEU, G. (1982). In vitro changes in gamma-aminobutyric acid output from the cerebral cortex induced by inhibitors of gamma-aminobutyric acid uptake and metabolism. J. Neurochem., 39, 582-584.
    • (1982) J. Neurochem. , vol.39 , pp. 582-584
    • Moroni, F.1    Mulas, A.2    Moneti, G.3    Pepeu, G.4
  • 31
    • 0028358569 scopus 로고
    • Effects of DAU 6215, a novel 5-hydroxytryptamine3 (5-HT3) antagonist on electrophysiological properties of the rat hippocampus
    • PASSANI, M.B., PUGLIESE, A.M., AZZURRINI, M. & CORRADETTI, R. (1994). Effects of DAU 6215, a novel 5-hydroxytryptamine3 (5-HT3) antagonist on electrophysiological properties of the rat hippocampus. Br. J. Pharmacol., 112, 695-703.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 695-703
    • Passani, M.B.1    Pugliese, A.M.2    Azzurrini, M.3    Corradetti, R.4
  • 32
    • 0027339314 scopus 로고
    • 5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat
    • PEI, Q., ZETTERSTROM, T., LESLIE, R.A. & GRAHAME-SMITH, D.G. (1993). 5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat. Eur. J. Pharmacol., 230, 63-68.
    • (1993) Eur. J. Pharmacol. , vol.230 , pp. 63-68
    • Pei, Q.1    Zetterstrom, T.2    Leslie, R.A.3    Grahame-Smith, D.G.4
  • 33
    • 0024207439 scopus 로고
    • Excitatory amino acid release from rat hippocampal slices as a consequence of free radical formation
    • PELLEGRINI-GIAMPIETRO, D.E., CHERICI, G., ALESIANI, M., CARLÀ, V. & MORONI, F. (1988). Excitatory amino acid release from rat hippocampal slices as a consequence of free radical formation. J. Neurochem., 51, 1960-1963.
    • (1988) J. Neurochem. , vol.51 , pp. 1960-1963
    • Pellegrini-Giampietro, D.E.1    Cherici, G.2    Alesiani, M.3    Carlà, V.4    Moroni, F.5
  • 34
    • 0025260736 scopus 로고
    • Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage
    • PELLEGRINI-GIAMPIETRO, D.E., CHERICI, G., ALESIANI, M., CARLÀ, V. & MORONI, F. (1990). Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J. Neurosci., 10, 1035-1041.
    • (1990) J. Neurosci. , vol.10 , pp. 1035-1041
    • Pellegrini-Giampietro, D.E.1    Cherici, G.2    Alesiani, M.3    Carlà, V.4    Moroni, F.5
  • 35
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation. II. Motor seizure
    • RACINE, R.J. (1972). Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol., 32, 281-294.
    • (1972) Electroencephalogr. Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 36
    • 0033047424 scopus 로고    scopus 로고
    • Nicotinic modulation of glutamate and GABA synaptic transmission of hippocampal neurons
    • RADCLIFFE, K.A., FISHER, J.L., GRAY, R. & DANI, J.A. (1999). Nicotinic modulation of glutamate and GABA synaptic transmission of hippocampal neurons. Ann. N.Y. Acad. Sci., 868, 591-610.
    • (1999) Ann. N.Y. Acad. Sci. , vol.868 , pp. 591-610
    • Radcliffe, K.A.1    Fisher, J.L.2    Gray, R.3    Dani, J.A.4
  • 37
    • 0025886943 scopus 로고
    • Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro
    • ROPERT, N. & GUY, N. (1991). Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro. J. Physiol., 441, 121-136.
    • (1991) J. Physiol. , vol.441 , pp. 121-136
    • Ropert, N.1    Guy, N.2
  • 38
    • 0025034301 scopus 로고
    • Characteristics of miniature inhibitory postsynaptic currents in CA1 pyramidal neurones of rat hippocampus
    • ROPERT, N., MILES, R. & KORN, H. (1990). Characteristics of miniature inhibitory postsynaptic currents in CA1 pyramidal neurones of rat hippocampus. J. Physiol., 428, 707-722.
    • (1990) J. Physiol. , vol.428 , pp. 707-722
    • Ropert, N.1    Miles, R.2    Korn, H.3
  • 39
    • 0024435336 scopus 로고
    • Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons
    • SAH, P., HESTRIN, S. & NICOLL, R.A. (1989). Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons. Science, 246, 815-818.
    • (1989) Science , vol.246 , pp. 815-818
    • Sah, P.1    Hestrin, S.2    Nicoll, R.A.3
  • 40
    • 0026611390 scopus 로고
    • Pharmacological characterization of GABAB-mediated responses in the CA1 region of the rat hippocampal slice
    • SOLIS, J.M. & NICOLL, R.A. (1992). Pharmacological characterization of GABAB-mediated responses in the CA1 region of the rat hippocampal slice. J. Neurosci., 12, 3466-3472.
    • (1992) J. Neurosci. , vol.12 , pp. 3466-3472
    • Solis, J.M.1    Nicoll, R.A.2
  • 41
    • 0031032949 scopus 로고    scopus 로고
    • Presynaptic nicotinic ACh receptors
    • WONNACOTT, S. (1997). Presynaptic nicotinic ACh receptors. Trends Neurosci., 20, 92-98.
    • (1997) Trends Neurosci. , vol.20 , pp. 92-98
    • Wonnacott, S.1
  • 42
    • 0025563403 scopus 로고
    • Neurotransmission in hepatic encephalopathy
    • ZENEROLI, M.L. & BARALDI, M. (1990). Neurotransmission in hepatic encephalopathy. Adv. Exp. Med. Biol., 272, 135-148.
    • (1990) Adv. Exp. Med. Biol. , vol.272 , pp. 135-148
    • Zeneroli, M.L.1    Baraldi, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.