Multiple enzymatic digestion for enhanced sequence coverage of proteins in complex proteomic mixtures using capillary LC with ion trap MS/MS

Journal of Proteome Research

Volumn 2, Issue 1, 2003, Pages 59-67

  Choudhary, Gargi ^a   Wu, Shiaw Lin ^a   Shieh, Paul ^a   Hancock, William S ^a  

^a Thermo Finnigan   (United States)

Author keywords

Ion trap mass spectrometry; Multiple enzymes; Plasma; Proteomics; Sequence coverage; Tissue plasminogen activator

Indexed keywords

ARGININE; ARGININE CARBOXYPEPTIDASE; ASPARAGINASE; ASPARTIC ACID; ENZYME; GLYCOPROTEIN; LYSINE; PEPTIDE; TISSUE PLASMINOGEN ACTIVATOR; TRYPSIN;

AMINO ACID SEQUENCE; ARTICLE; CAPILLARY CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEOMICS;

AMINO ACID SEQUENCE; ASPARTIC ACID; ASPARTIC ENDOPEPTIDASES; BLOOD PROTEINS; CHROMATOGRAPHY; ENDOPEPTIDASES; GLYCOPROTEINS; HUMANS; IONS; LYSINE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEOME; RECOMBINANT PROTEINS; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TRYPSIN;

EID: 0037274605     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr025557n     Document Type: Article

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