Mitral cell β1 and 5-HT2A receptor colocalization and camp coregulation: A new model of norepinephrine-induced learning in the olfactory bulb

Learning and Memory

Volumn 10, Issue 1, 2003, Pages 5-15

  Yuan, Qi ^a   Harley, Carolyn W ^a   McLean, John H ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ISOPRENALINE; NORADRENALIN; SEROTONIN 2A RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; SEROTONIN; SEROTONIN 2C RECEPTOR; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; LOCUS CERULEUS; MALE; MITRAL CELL; NONHUMAN; NORADRENERGIC SYSTEM; ODOR; OLFACTORY BULB; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; SMELLING; TACTILE STIMULATION; ANIMAL; CONDITIONED REFLEX; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; LEARNING; METABOLISM; OLFACTORY NERVE; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADRENERGIC BETA-AGONISTS; ANIMALS; CONDITIONING, CLASSICAL; CYCLIC AMP; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; ISOPROTERENOL; LEARNING; LOCUS COERULEUS; MICROSCOPY, CONFOCAL; NOREPINEPHRINE; ODORS; OLFACTORY BULB; OLFACTORY NERVE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, SEROTONIN; SEROTONIN;

EID: 0037268372     PISSN: 10720502     EISSN: None     Source Type: Journal    
DOI: 10.1101/lm.54803     Document Type: Article

References (66)

1. Abel, T., Nguyen, P.V., Barad, M., Deuel, T.A., Kandel, E.R., and Bourtchouladze, R. 1997. Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell 88: 615-626.
2. Ang, K.L. and Antoni, F.A. 2002. Reciprocal regulation of calcium dependent and calcium independent cyclic AMP hydrolysis by protein phosphorylation. J. Neurochem. 81: 422-433.
3. Barad, M., Bourtchouladze, R., Winder. D.G., Golan, H., and Kandel, E. 1998. Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc. Natl. Acad. Sci. 95: 15020-15025.
4. 2+- and stimulus duration-dependent switch for hippocampal gene expression. Cell 87: 1203-1214.
5. Blitzer, R.D. Wong, T., Nouranifar, R., Iyengar, R., and Landau, E.M. 1995. Postsynaptic cAMP pathway gates early LTP in hippocampal CA1 region. Neuron 15: 1403-1414.
6. Brunelli, M., Castellucci, V., and Kandel, E.R. 1976. Presynaptic facilitation as a mechanism for behavioral sensitization in Aplysia. Science 194: 1176-1180.
7. Byers, D., Davis, R.L., and Kiger Jr., J.A. 1981. Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster. Nature 289: 79-81.
8. Cattoretti, C., Pileri, S., Parravicini, C., Becker, M.H., Poggi, S., Bifulco, C., Key, G., D'Amato, L., Sabattini, E., Feudale, E., et al. 1993. Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections. J. Pathol. 171: 83-98.
9. Chakraborti, S., Chakraborti, T., and Shaw, G. 2000. β-Adrenergic mechanisms in cardiac diseases: A perspective. Cell. Signal. 12: 499-513.
10. 2A receptor in the central nervous system of adult rat. J. Comp. Neurol. 409: 187-209.
11. Czesnik, D., Nezlin, L., Rabba, J., Muller, B., and Schild, D. 2002. Noradrenergic modulation of calcium currents and synaptic transmission in the olfactory bulb of Xenopus laevis tadpoles. Eur. J. Neurosci. 13: 1093-1100.
12. Davis, R.L., Cherry, J., Dauwalder, B., Han, P.L., and Skoulakis, E. 1995. The cyclic AMP system and Drosophila learning. Mol. Cell. Biochem. 149-150: 271-278.
13. Deisseroth, K., Bito, H., and Tsien, R.W. 1996. Signaling from synapse to nucleus: Postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity. Neuron. 16: 89-101.
14. English, J.D. and Sweatt, J.D. 1997. A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation. J. Biol. Chem. 272: 19103-19106.
15. 1251]iodocyanopindolol binding sites. Cell. Mol. Neurobiol. 17: 401-415.
16. 2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken. Mol. Brain. Res. 54: 199-211.
17. 2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron 21: 869-883.
18. Ivins, K.J., Ibrahim, E., and Leon, M. 1993. Localization of β-adrenergic receptor mRNA in the olfactory bulb of neonatal rats. Soc Neurosci. Abst. 19: 124.
19. Jiao, Y., Sun, Z., Lee, T., Fusco, F.R., Kimble, T.D., Meade, C.A., Cuthbertson, S., and Reiner, A. 1999. A simple and sensitive antigen retrieval method for free-floating and slide-mounted tissue sections. J. Nearosci. Methods 93: 149-162.
20. Kandel, E.R., Schwartz, J.H., and Jessel, T.M. 2000. Cellular mechanisms of learning and the biological basis of individuality. In Principles of neural science (eds. E.R. Kandel et al.), pp. 1252-1254. McGraw-Hill, New York.
21. Karle, C.A., Zitron, E., Zhang, W., Kathofer, S., Schoels, W., and Kiehn, J. 2002. Rapid component I(Kr) of the guinea-pig cardiac delayed rectifier K(+) current is inhibited by β(1)-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways. Cardiovasc. Res. 53: 355-362.
22. Langdon, P.E., Harley, C.W., and McLean, J.H. 1997. Increased β adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonin depletion. Dev. Brain. Res. 102: 291-293.
23. Liu, F.-C. and Graybiel, A.M. 1996. Spatiotemporal dynamics of CREB phosphorylation: Transient versus sustained phosphorylation in the developing striatum. Neuron 17: 1133-1144.
24. Madison, D.V. and Nicoll, R.A. 1986. Cyclic adenosine 3′,5′-monophosphate mediates β-receptor actions of noradrenaline in rat hippocampal pyramidal cells. J. Physiol. (Lond.) 372: 245-259.
25. McLean, J.H., Darby-King, A., Sullivan, R.M., and King, S.R. 1993. Serotonergic influence on olfactory learning in the neonate rat. Behav. Neural Biol. 60: 152-162.
26. 2A receptor mRNA by in situ hybridization in the olfactory bulb of the postnatal rat. J. Comp. Neurol. 353: 371-378.
27. 2 receptor involvement in conditioned olfactory learning in the neonate rat pup. Behav. Neurosci. 110: 1426-1434.
28. McLean, J.H., Harley, C.W., Darby-King, A., and Yuan, Q. 1999. pCREB in the neonate rat olfactory bulb is selectively and transiently increased by odor preference-conditioned training. Learn. Mem. 6: 608-618.
29. 2+/calmodulin-stimulable adenylyl cyclases as molecular coincidence detectors in memory formation. Cell. Mol. Life. Sci. 55: 525-533.
30. Morin, D., Sapena, R., Zini, R., and Tillement, J.-P. 1992. Serotonin enhances the β-adrenergic response in rat brain cortical slices. Eur. J. Pharmacol. 225: 273-274.
31. Mouly, A.M., Elaagouby, A., and Ravel, N. 1995. A study of the effects of noradrenaline in the rat olfactory bulb using evoked field potential response. Brain. Res. 681: 47-57.
32. Nicholas, A.P., Pieribone, V.A., and Hokfelt, T. 1993. Cellular localization of messenger RNA for β-1 and β-2 adrenergic receptors in rat brain: An in situ hybridization study. Neuroscience 56: 1023-1039.
33. Okutani, F., Kaba, H., Takahashi, S., and Seto, K. 1998. The biphasic effects of focus coeruleus noradrenergic activation on dendrodendritic inhibition in the rat olfactory bulb. Brain. Res. 783: 272-279.
34. Ozacmak, V.H., Thorington, G.U., Fletcher, W.H., and Hessinger, D.A. 2002. N-Acetylneuraminic acid (NANA) stimulates in situ cyclic AMP production in tentacles of sea anemone (Aiptasia pallida): Possible role in chemosensitization of nematocyst discharge. J. Exp. Biol. 204: 2011-2020.
35. 2C receptors. Mol. Brain. Res. 23: 163-178.
36. 2+-stimulated adenylyl cyclases in LTP and memory formation. Int. J. Dev. Neurosci. 19: 387-394.
37. Price, T.L., Darby-King, A., Harley, C.W., and McLean, J.H. 1998. Serotonin plays a permissive role in conditioned olfactory learning induced by norepinephrine in the neonate rat. Behav. Neurosci. 112: 1430-1437.
38. Rangel, S. and Leon, M. 1995. Early odor preference training increases olfactory bulb norepinepbrine. Dev. Brain. Res. 85: 187-191.
39. Rovescalli, A.C., Brunello, N., Perez, J., Vitali, S., Steardo, L., and Racagni, G. 1993. Heterologous sensitization of adenylate cyclase activity by serotonin in the rat cerebral cortex. Eur. Neuropsychopharmacol. 3: 463-475.
40. Shi, S.R., Key, M.E., and Kalra, K.L. 1991. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J. Histochem. Cytochem. 39: 741-748.
41. Shieh, P.B., Hu, S.C., Bobb, K., Timmusk, T., and Ghosh, A. 1998. Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20: 727-740.
42. Sullivan, R.M. and Leon, M. 1987. One-trial olfactory learning enhances olfactory bulb responses to an appetitive conditioned odor in 7-day-old rats. Dev. Brain. Res. 35: 307-311.
43. Sullivan, R.M. and Wilson, D.A. 1994. The locus coeruleus, norepinephrine, and memory in newborns. Brain. Res. Bull. 35: 467-472.
44. Sullivan, R.M., Wilson, D.A., and Leon, M. 1989. Norepinephrine and learning-induced plasticity in infant rat olfactory sytem. J. Neurosci. 9: 3998-4006.
45. Sullivan, R.M., McGaugh, J.L., and Leon, M. 1991. Norepinephrine-induced plasticity and one-trial olfactory learning in neonatal rats. Dev. Brain. Res. 60: 219-228.
46. Sullivan, R.M., Landers, M., Yeaman, B., and Wilson, D.A. 2000a. Good memories of bad events in infancy. Nature 407: 38-39.
47. Sullivan, R.M., Stackenwalt, G., Nasr, F., Lemon, C., and Wilson, D.A. 2000b. Association of an odor with activation of olfactory bulb noradrenergic β-receptors or locus coeruleus stimulation is sufficient to produce learned approach responses to that odor in neonatal rats. Behav. Neurosci. 114: 957-962.
48. 1-adrenergic receptor. Proc. Natl. Acad. Sci. 96: 12559-12564.
49. 2+ channel activation regulates c-fos transcription at multiple levels. J. Biol. Chem. 270: 4224-4235.
50. Trombley, P.Q. 1992. Norepinephrine inhibits calcium currents and EPSPs via a G-protein-coupled mechanism in olfactory bulb neurons. J. Neurosci. 12: 3992-3998.
51. Trombley, P.Q. 1994. Noradrenergic modulation of synaptic transmission between olfactory bulb neurons in culture: Implications to olfactory learning. Brain. Res. Bull 35: 473-484.
52. Trombley, P.Q. and Shepherd, G.M. 1992. Noradrenergic inhibition of synaptic transmission between mitral and granule cells in mammalian olfactory bulb cultures. J. Neurosci. 12: 3985-3991.
53. Wanaka, A., Kiyama, H., Murakami, T., Matsumoto, M., Kamada, T., Malbon, C.C., and Tohyama, M. 1989. Immunocytochemical localization of β-adrenergic receptors in the rat brain. Brain. Res. 485: 125-140.
54. Werstiuk, E.S. and Lee, R.M. 2000. Vascular β-adrenoceptor function in hypertension and in ageing. Can. J. Physiol. Pharmacol. 78: 433-452.
55. Wiemer, G., Hellwich, U., Wellstein, A., Dietz, J., Hellwich, M., and Palm, D. 1982. Energy-dependent extrusion of cyclic 3′,5′-adenosine-monophosphate. A drug-sensitive regulatory mechanism for the intracellular nucleotide concentration in rat erythrocytes. Naunyn. Schmiedebergs. Arch. Pharmacol. 321: 239-246.
56. Wilson, D.A. and Leon, M. 1988. Noradrenergic modulation of olfactory bulb excitability in the postnatal rat. Dev. Brain. Res. 42: 69-75.
57. Wilson, D.A., Sullivan, R.M., and Leon, M. 1987. Single-unit analysis of postnatal olfactory learning: Modified olfactory bulb output response patterns to learned attractive odors. J. Neurosci. 7: 3154-3162.
58. Winder, D.G., Mansuy, I.M., Osman, M., Moallem, T.M., and Kandel, E.R. 1998. Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin. Cell 92: 25-37.
59. Wong, S.T., Athos, J., Figueroa, X.A., Pineda, V.V., Schaefer, M.L., Chavkin, C.C., Muglia, LJ., and Storm, D.R. 1999. Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP. Neuron 23: 787-798.
60. Woo, C.C. and Leon, M. 1995. Distribution and development of &-adrenergic receptors in the rat olfactory bulb. J. Comp. Neurol. 352: 1-10.
61. Woo, C.C., Wilson, D.A., Sullivan, R.M., and Leon, M. 1996. Early locus coeruleus lesions increase the density of &-adrenergic receptors in the main olfactory bulb of rats. Int. J. Dev. Neurosci. 14: 913-919.
62. Xing, J., Kornhauser, J.M., Xia, Z., Thiele, E.A., and Greenberg, M.E. 1998. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol. Cell. Biol. 18: 1946-1955.
63. Yu, H.J., Ma, H., and Green, R.D. 1993. Calcium entry via L-type calcium channels acts as a negative regulator of adenylyl cyclase activity and cyclic AMP levels in cardiac myocytes. Mol. Pharmacol. 44: 689-693.
64. Yuan, Q., Harley, C.W., Bruce, A.J., Darby-King, A., and McLean, J.H. 2000. Isoproterenol increases CREB phosphorylation and olfactory nerve-evoked potentials in normal and 5-HT-depleted olfactory bulbs in rat pups only at doses that produce odor preference learning. Learn. Mem. 7: 413-421.
65. Yuan, Q., Harley, C.W., McLean, J.H., and Knopfel, T. 2002. Optical imaging of odor preference memory in the rat olfactory bulb. J. Neurophysiol. 87: 3156-3159.
66. Zhong, Y., Budnik, V., and Wu, C. 1992. Synaptic plasticity in Drosophila memory and hyperexcitable mutants: Role of cAMP cascade. J. Neurosci. 12: 644-651.