Interferon-γ gene microsatellite polymorphisms in patients with Graves' disease

Thyroid

Volumn 8, Issue 11, 1998, Pages 1013-1017

  Siegmund, Thorsten ^a   Usadel, Klaus H ^a   Donner, Horst ^a   Braun, Jens ^a   Walfish, Paul G ^b   Badenhoop, Klaus ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOTIDE; GAMMA INTERFERON; HLA DQ ANTIGEN; MICROSATELLITE DNA;

ALLELE; ARTICLE; CAUCASIAN; CHROMOSOME 12Q; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; ENDOCRINE OPHTHALMOPATHY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GRAVES DISEASE; HUMAN; MAJOR CLINICAL STUDY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031741704     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.1998.8.1013     Document Type: Article

References (32)

1. Weetman AP, McGregor AM 1994 Autoimmune thyroid disease: Further developments in our understanding. Endocr Rev 15:788-830.
2. Badenhoop K, Walfish PG, Rau H, Fischer S 1995 Susceptibility and resistance alleles of human leucocyte antigen (HLA) DQA1 and DQB1 are shared in endocrine autoimmune disease. J Clin Endocrinol Metab 80:2112-2117.
3. Payami H, Joe S, Farid NR Stenszky V 1989 Relative predisposonal effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves' disease. Am J Hum Genet 45:541-546.
4. Yanagawa T, Manklabruks A, Chang YB Okamoto Y 1993 Human histocompatibility complex leucocyter antigen DAQ1 0501 allele associated with genetic susceptibility to Graves' disease in Caucasian population. J Clin Endocrinol Metab 76:1574.
5. McLachlan SM 1993 The genetic basis of autoimmune thyroid disease: Time to focus on chromosomal loci other than the major histicompatibility complex (HLA in man). J Clin Endocrinol Metab 77:605(A)-605(C).
6. Roman SH, Greenberg D, Rubinstein P, Wallenstein S, Davies TF 1992 Genetics of autoimmune thyroid disease: Lack of evidance for linkage to HLA within families. J Clin Endocrinol Metab 74:496-503.
7. Badenhoop K, Schwarz G, Schleusener G, Weetman AP 1992 Tumor necrosis factor beta gene polymorphisms in Graves' disease. J Clin Endocrinol Metab 74:287-291.
8. Yanagawa T, Hidaka Y, Guimaraes V, Soliman M, De Groot LJ 1995 CTLA-4 gene polymorphism associated with Graves' disease in Caucasian population. J Clin Endocrinol Metab 80:41-45.
9. Farid NR, Stensky V 1988 Graves' disease. In: Farid NR (ed) Immunogenetics of Endocrine Disorders. Liss, New York, pp 223-266.
10. Da vies TF 1992 New thinking on the immunology of Graves' disease. Thyroid Today 15:1-11.
11. Donner H, Rau H, Walfish PG, Braun J 1997 CTLA4 Alanine-17 confers genetic susceptibility to Graves' disease and type I diabetes mellitus. J Clin Endocrinol Metab 82:143-146.
12. Tomer Y, Barbesino G, Keddache M, Greenberg DA 1997 Mapping of a major susceptibility locus for Graves' disease (GD-1) to chromosome 14q31. J Clin Endocrinol Metab 82:1645-1648.
13. Gray PW, Goeddel DV 1982 Structure of the human interferon gene. Nature 298:859-863.
14. Young HA, Hardy KJ 1990 Interferon-gamma: Producer cells, activation stimuli, and molecular genetic regulation. Pharmacol Ther 45:137-151.
15. Hanafusa T, Pujol-Borell R, Chiovato 1993 Aberrant expression of HLA-DR antigen on thyreocytes of Graves' disease. Relevance for Graves' disease. Lancet ii:1111.
16. Hamilton F, Black M, Farquharson MA 1991 Spatial correlation between thyroid epithelial cells expressing class II MHC molecules and IFN-gamma containing lymphocytes in human thyroid autoimmune disease. Clin Exp Immunol 83:64-68.
17. Margolick JB, Weetman AP, Burman KD 1988 Immunohistochemical analysis of intrathyroidal lymphocytes in Graves' disease: Evidence of activated T cells and production of IFN-gamma. Clin Immunol Immunopathol 47:208-218.
18. Heuer M, Aust G, Ode-Hakim S 1996 Different cytokine mRNA profiles in Graves' disease, HT, and non-autoimmune thyreoid disorders determined by quantitative reverse transcriptase polymerase chain reaktion. Thyroid 6:97-106.
19. Todd I, Pujol-Borell R, Hammond LJ 1985 Interferon-gamma induces HLA-DR expression by thyroid epithelium. Clin Exp Immunol 61:265-273.
20. Trinchieti G 1989 Biology of natural killer cells. Adv Immunol 146:3074.
21. Manetti R, Parrouchi P, Guidici MG, Piccini MP 1993 Natural killer cell stimulating factor (IL 12) induces T helper 1 (TH1) specific immune response and inhibits the development of IL4 producing T helper cells. J Exp Med 177:1199-1204.
22. von Herrath MG, Oldstone MB 1997 Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus. J Exp Med 185:531-539.
23. Zipris D, Greiner DL, Malkani S, Whalen B, Mordes JP, Rossini AA 1996 Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. J Immunol 156:1315-1321.
24. Nicoletti F, Zaccone P, Di Marco R, Lunetta M, Magro G, Grasso S, Meroni P, Garotta G 1997 Prevention of spontaneous autoimmune diabetes in diabetes-prone BB rats by prophylactic treatment with antirat interferon-gamma antibody. Endocrinology 138:281-288.
25. Watson PF, Pickerin AP, Davies R, Weetman AP 1994 Analysis of cytokine gene expression in Graves' disease and multinodular goiter. J Clin Endocrinol Metab 79:355-360.
26. Awata T, Matsumoto C, Urakami T, Hagura R, Amemiya S, Kanazawa Y 1994 Association of polymorphism in the interferon-gamma gene with IDDM. Diabetologia 37: 1159-1162.
27. Van Dyk HJ 1881 Orbital Graves' disease. A modification of the "No SPECS" classification. Ophthalmopathy 88(6): 479-188.
28. Bottazzo GF, Pujol-Borell R, Hanafusa T 1983 Role of aberrant HLA-DR expression and antigen presentation in introduction of endocrine autoimmunity. Lancet ii:1115.
29. Vafiadis P, Bennet ST, Todd JA, Nadeau J, Grabs R, Goodyer CG, Wickramasinghe S, Colle E, Polychronakos C 1997 Insulin expression in human thymus is modulated by INS VNTR alleles in the IDDM2 locus. Nat Genet 15:289-292.
30. Pugliese A, Zeller M, Fernandez A Jr, Zalcberg LJ, Bartlett RJ, Ricordi C, Pietropaolo M, Eisenbarth GS, Bennet ST, Patel DD 1997 The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation in INS VNTR-IDDM2 susceptibility locus for type I diabetes. Nat Genet 15:293-297.
31. Segel LA, Jäger E, Elias D 1995 A quantitative model of autoimmune disease and T cell vacination: Does more mean less. Immunol Today 16:80-84.
32. Paschke R, Schuppert F, Taton M, Velu T 1994 Intrathyroidal cytokine gene expression profiles in autoimmune thyroiditis. Endocrinology 2:309-315.