Synthesis and localization of pancreatic secretory proteins in pancreatic acinar-like metaplasia in the distal part of the oesophagus: Pancreatic acinar metaplasia: Another source of pancreatic enzymes!

Scandinavian Journal of Gastroenterology

Volumn 38, Issue 1, 2003, Pages 10-13

  Håkansson, Hans Olof ^a   Mellblom, L ^a   Johansson, J ^a   Bjartell, A ^a   Borgstrom A ^a  

^a Dept of Surgery ^*

Author keywords

Intestinal metaplasia; Oesophagus; Pancreatic acinar metaplasia (PAM); Pancreatic elastase; Pancreatic enzymes; Pancreatic secretory trypsin inhibitor (PSTI); Procarboxypeptidase B; Trypsin

Indexed keywords

ALKALINE PHOSPHATASE; CARBOXYPEPTIDASE B; CELL PROTEIN; ELASTASE; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE; PANCREATIC SECRETORY PROTEIN; TRYPSIN INHIBITOR; TRYPSINOGEN; TRYPSINOGEN 2; UNCLASSIFIED DRUG;

ACINAR CELL; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONJUGATION; DNA PROBE; ESOPHAGUS DISEASE; GASTROSCOPY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; METAPLASIA; MICROSCOPIC ANATOMY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RNA ANALYSIS; STOMACH MUCOSA;

EID: 0037255274     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365521.2003.11800650     Document Type: Article

References (18)

1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997;25:3389-402.
2. Appelros S, Thim L, Borgström A. Activation peptide from carboxypeptidase B in serum and urin in acute pancreatitis. Gut 1998;42:97-102.
3. Bjartell A, Malm J, Möller C, Gunnarsson M, Lundwall Å, Lilja H. Distribution and tissue expression of Semenogelin I and II in man as demonstrated by in situ-hybridization and immunocytochemistry. J Androl 1996;17:17-26.
4. Bohe M, Borgström A, Lindström C, Ohlsson K. Pancreatic endoproteases and pancreatic secretory trypsin inhibitor immunoreactivity in human paneth cell. J Clin Pathol 1986:786-93.
5. DeMeester SR, DeMeester TR. Columnar mucosa and intestinal metaplasia of the esophagus. Ann Surg 2000;231:303-21.
6. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis, the updated Sydney System. Am J Surg Pathol 1996;20:1161-81.
7. Doglioni C, Laurino L, Dei Tos AP. Pancreatic acinar metaplasia of the gastric mucosa. Am J Surg Pathol 1993;17:1134-43.
8. Hashimoto K, Sugiyama H. Treatment of postgastrectomy reflux esophagitis; with special reference to the pathogenisis (in Japanese with English summary). Prog Med 1993;12:512-8.
9. Imada T, Chen C, Hatori S, Shiozawa M, Rino Y. Effect of trypsin inhibitor on reflux oesophagitis after total gastrectomy in rats. Eur J Surg 1999;165:1045-50.
10. Johansson J, Håkansson H-O, Mellblom L, Kempas A, Borgström A, Johansson K-E, Nyren O. Prevalence of intestinal and other types of columnar metaplasia in the distal oesophagus and at the gastro-oesophageal junction. In manuscript.
11. Koop H. Reflux disease and Barrett's esophagus. Endoscopy 2000;32:101-7.
12. Lagergren J, Bergström R, Lindgren A, Nyren O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 1999;340:825-31.
13. McArdle JE, Lewin KJ, Randell G, Weinstein W. Distribution of dysplasia and early invasive carcinoma in Barrett's esophagus. Human Pathol 1992;23:479-82.
14. Ohlsson K, Olsson A. Hoppe-Seyler's Z Physiol Chem 1976;357:1153-61.
15. Paju A, Bjartell A, Zhang W-M, Nordling S, Borgström A, Hansson J, Stenman U-H. Expression and Characterization of Trypsinogen Produced in the Human Male Genital Tract. Am J Pathol. 2000;157:2011-21.
16. Sipponen P, Marshall BJ. Gastritis and gastric cancer. Gastroenterol Clin North Am 2000;29:579-92.
17. Vaezi MF, Richter JE. Synergism of acid and duodenogastroesophageal reflux in complicated Barrett's esophagus. Surgery 1995;117:699-704.
18. Wang HH, Zeroogian JM, Spechler SJ, Goyal RJ, Antoniolo DA Am J Surg Pathol 1996;20:1507-10.