Increase in dephosphorylation of the heavy neurofilament subunit in the monkey chronic glaucoma model

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 1, 2003, Pages 154-159

  Kashiwagi, Kenji ^a   Ou, Bo ^a   Nakamura, Shinichiro ^b   Tanaka, Yuko ^a   Suzuki, Michihiro ^c   Tsukahara, Shigeo ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

^c Corp Prod/Res of Lab Primates ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROFILAMENT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; DEPHOSPHORYLATION; GLAUCOMA; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MACACA; NERVE CELL LESION; NERVE FIBER TRANSPORT; NEUROFILAMENT; NONHUMAN; OPTIC CHIASM; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RETINA; RETINA GANGLION CELL;

ANIMALS; AXONS; BLOTTING, WESTERN; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLAUCOMA; INTRAOCULAR PRESSURE; MACACA; NEUROFILAMENT PROTEINS; OPTIC CHIASM; OPTIC DISK; OPTIC NERVE DISEASES; PHOSPHORYLATION; PROTEIN ISOFORMS; RETINAL GANGLION CELLS;

EID: 0037252934     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.02-0398     Document Type: Article

References (36)

1. Lee MK, Cleveland DW. Neuronal intermediate filaments. Annu Rev Neurosci. 1996;19:187-217.
2. Leterrier JF, Kas J, Hartwig J, Vegners R, Janmey PA. Mechanical effects of neurofilament cross-bridges: modulation by phosphorylation, lipids, and interactions with F-actin. J Biol Chem. 1996;271:15687-15694.
3. Nixon RA, Sihag RK. Neurofilament phosphorylation: a new look at regulation and function. Trends Neurosci. 1991;14:501-506.
4. Pant HC, Veeranna. Neurofilament phosphorylation. Biochem Cell Biol. 1995;73:575-592.
5. Veeranna, Amin ND, Ahn NG, et al. Mitogen-activated protein kinases (Erk1, 2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M. J Neurosci. 1998;18:4008-4021.
6. Minckler DS, Bunt AH, Johanson GW. Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey. Invest Ophthalmol Vis Sci. 1977;16:426-441.
7. Minckler DS, Tso MO, Zimmerman LE. A light microscopic, autoradiographic study of axoplasmic transport in the optic nerve head during ocular hypotony, increased intraocular pressure and papilledema. Am J Ophthalmol. 1976;82:741-757.
8. Quigley HA, Addicks EM, Green WR, Maumenee AE. Optic nerve damage in human glaucoma. II: the site of injury and susceptibility to damage. Arch Ophthalmol. 1981;99:635-649.
9. Vickers JC, Schumer RA, Podos SM, et al. Differential vulnerability of neurochemically identified subpopulations of retinal neurons in a monkey model of glaucoma. Brain Res. 1995;680:23-35.
10. Quigley HA, Hohman RM. Laser energy levels for trabecular meshwork damage in the primate eye. Invest Ophthalmol Vis Sci. 1983;24:1305-1307.
11. Fukuchi T, Sawaguchi S, Yue BY, et al. Sulfated proteoglycans in the lamina cribrosa of normal monkey eyes and monkey eyes with laser-induced glaucoma. Exp Eye Res. 1994;58:231-243.
12. Eckersley L, Ansselin AD, Tomlinson DR. Effects of experimental diabetes on axonal and Schwann cell changes in sciatic nerve isografts. Brain Res Mol Brain Res. 2001;92:128-137.
13. Tokuoka H, Saito T, Yorifuji H, et al. Brain-derived neurotrophic factor-induced phosphorylation of neurofilament-H subunit in primary cultures of embryo rat cortical neurons. J Cell Sci. 2000;113:1059-1068.
14. Vickers JC, Hof PR, Schumer RA, et al. Magnocellular and parvocellular visual pathways are both affected in a macaque monkey model of glaucoma. Aust NZJ Ophthalmol. 1997;25:239-243.
15. Vickers JC, Lazzarini RA, Riederer BM, Morrison JH. Intraperikaryal neurofilamentous accumulations in a subset of retinal ganglion cells in aged mice that express a human neurofilament gene. Exp Neurol. 1995;136:266-269.
16. Julien JP, Mushynski WE. Neurofilaments in health and disease. Prog Nucleic Acids Res. 1998;61:1-23.
17. McLean WG. The role of axonal cytoskeleton in diabetic neuropathy. Neurochem Res. 1997;22:951-956.
18. Terada S, Nakata T, Peterson AC, Hirokawa N. Visualization of slow axonal transport in vivo. Science. 1996;273:784-788.
19. Hisanaga S, Hirokawa N. Dephosphorylation-induced interactions of neurofilaments with microtubules. J Biol Chem. 1990;265:21852-21858.
20. Hirokawa N, Glicksman MA, Willard MB. Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton. J Cell Biol. 1984;98:1523-1536.
21. Sun D, Leung CL, Liem RK. Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35. J Biol Chem. 1996;271:14245-14251.
22. Hisanaga S, Uchiyama M, Hosoi T, et al. Porcine brain neurofila ment-H tail domain kinase: its identification as cdk5/p26 complex and comparison with cdc2/cyclin B kinase. Cell Motil Cytoskeleton. 1995;31:283-297.
23. Hisanaga S, Ishiguro K, Uchida T, et al. Tau protein kinase II has a similar characteristic to cdc2 kinase for phosphorylating neurofilament proteins. J Biol Chem. 1993;268:15056-15060.
24. Shetty KT, Link WT, Pant HC. cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization. Proc Natl Acad Sci USA. 1993;90:6844-6848.
25. Giasson BI, Mushynski WE. Aberrant stress-induced phosphorylation of perikaryal neurofilaments. J Biol Chem. 1996;271:30404-30409.
26. Giasson BI, Mushynski WE. Study of proline-directed protein kinases involved in phosphorylation of the heavy neurofilament subunit. J Neurosci. 1997;17:9466-9472.
27. Quigley HA, McKinnon SJ, Zack DJ, et al. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophthalmol Vis Sci. 2000;41:3460-3466.
28. Pease ME, McKinnon SJ, Quigley HA, Kerrigan-Baumrind LA, Zack DJ. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Invest Ophthalmol Vis Sci. 2000;41:764-774.
29. Gotow T, Tanaka T, Nakamura Y, Takeda M. Dephosphorylation of the largest neurofilament subunit protein influences the structure of crossbridges in reassembled neurofilaments. J Cell Sci. 1994;107:1949-1957.
30. Beatty S, Good PA, McLaughlin J, O'Neill EC. Correlation between the orbital and intraocular portions of the optic nerve in glaucomatous and ocular hypertensive eyes. Eye. 1998;12:707-713.
31. Dichtl A, Jonas JB. Echographic measurement of optic nerve thickness correlated with neuroretinal rim area and visual field defect in glaucoma. Am J Ophthalmol. 1996;122:514-519.
32. Beatty S, Good PA, McLaughlin J, O'Neill EC. Echographic measurements of the retrobulbar optic nerve in normal and glaucomatous eyes. Br J Ophthalmol. 1998;82:43-47.
33. Sawaguchi S, Abe H, Fukuchi T, et al. Slow axonal transport in primate experimental glaucoma [in Japanese]. Nippon Ganka Gakkai Zasshi. 1996;100:132-138.
34. Ou B, Ohno S, Tsukahara S. Ultrastructural changes and immunocytochemical localization of microtubule-associated protein 1 in guinea pig optic nerves after acute increase in intraocular pressure. Invest Ophthalmol Vis Sci. 1998;39:963-971.
35. Yucel YH, Zhang Q, Weinreb RN, Kaufman PL, Gupta N. Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma. Invest Ophthalmol Vis Sci. 2001;42:3216-3222.
36. Yucel YH, Zhang Q, Gupta N, Kaufman PL, Weinreb RN. Loss of neurons in magnocellular and parvocellular layers of the lateral geniculate nucleus in glaucoma. Arch Ophthalmol. 2000;118:378-384.