Mucin gene expression in the effusions of otitis media with effusion

International Journal of Pediatric Otorhinolaryngology

Volumn 67, Issue 1, 2003, Pages 53-58

  Takeuchi, Kazuhiko ^a   Yagawa, Mayuko ^a   Ishinaga, Hajime ^a   Kishioka, Chikako ^a   Harada, Teruhiko ^a   Majima, Yuichi ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Gene expression; Middle ear effusion; Mucin; RT PCR

Indexed keywords

MESSENGER RNA; MUCIN;

ADULT; AGED; ARTICLE; BRONCHUS MUCOSA; CELL CULTURE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; MALE; MIDDLE EAR EFFUSION; OTITIS MEDIA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION;

ADULT; AGED; CHILD; DNA PRIMERS; FEMALE; GENE EXPRESSION; GLYCOPROTEINS; HUMANS; MALE; MEMBRANE PROTEINS; MUCINS; OTITIS MEDIA WITH EFFUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0037252722     PISSN: 01655876     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5876(02)00361-0     Document Type: Article

References (18)

1. Rose M.C., Gendler S.J. Airway mucin genes and gene products. Raeburn D., Giembycz M. Airway Mucus: Basic Mechanisms and Clinical Perspectives. 1997;41-66 Birkhaeuser Verlag, Basel.
2. Williams S.J., McGuckin M.A., Gotley D.C., Eyre H.J., Sutherland G.R., Antalis T.M. Two novel mucin genes down-regulated in colorectal cancer identified by differential display. Cancer Res. 59:1999;4083-4089.
3. Audie J.P., Janin A., Porchet N., Copin M.C., Gosselin B., Aubert J.P. Expression of human mucin genes in respiratory, digestive and reproductive tracts ascertained by in situ hybridization. J. Histochem. Cytochem. 41:1993;1479-1485.
4. Aust M.R., Madsen C.S., Jennings A., Kasperbauer J.L., Gendler S.J. Mucin mRNA expression in normal and vasomotor inferior turbinates. Am. J. Rhinol. 11:1997;293-302.
5. Kawano H., Paparella M.M., Ho S.B., Schachern P.A., Morizono N., Le C.T., et al. Identification of MUC5B mucin gene in human middle ear with chronic otitis media. Laryngoscope. 110:2000;668-673.
6. Moon S.K., Lim D.J., Lee H.K., Kim H.N., Yoo J.H. Mucin gene expression in cultured human middle ear epithelial cells. Acta Otolaryngol. 120:2000;933-939.
7. Wezyk M.T., Makowski A., Krawczyk T. Cytological picture of fluid collected from middle ear in course of o.m.s. in children. Otolaryngol. Pol. 54:2000;431-437.
8. Noah T.L., Yankaskas J.R., Carson J.L., Gambling T.M., Cazares L.H., McKinnon K.P., et al. Tight junctions and mucin mRNA in BEAS-2B cells. In Vitro Cell Dev. Biol. Anim. 31:1995;738-740.
9. Chen Y.P., Tong H.H., James, Demaria T.F. Detection of mucin gene expression in normal rat middle ear mucosa by reverse transcriptase-polymerase chain reaction. Acta Otolaryngol. 121:2001;45-51.
10. Lin J., Haruta A., Kawano H., Ho S.B., Adams G.L., Juhn S.K., et al. Induction of mucin gene expression in middle ear of rats by tumor necrosis factor-alpha: potential cause for mucoid otitis media. J. Infect. Dis. 182:2000;882-887.
11. Smirnova M.G., Birchall J.P., Pearson J.P. TNF-alpha in the regulation of MUC5AC secretion: some aspects of cytokine-induced mucin hypersecretion on the in vitro model. Cytokine. 12:2000;1732-1736.
12. Smirnova M.G., Kiselev S.L., Birchall J.P., Pearson J.P. Up-regulation of mucin secretion in HT29-MTX cells by the pro-inflammatory cytokines tumor necrosis factor-a and interleukin-6. Eur. Cytokine Netw. 12:2001;119-215.
13. Tsuboi Y., Kim Y., Paparella M.M., Chen N., Schachern P.A., Lin J. Pattern changes of mucin gene expression with pneumococcal otitis media. Int. J. Pediatr. Otorhinolaryngol. 61:2001;23-30.
14. Hutton D.A., Fogg F.J., Kubba H., Birchall J.P., Pearson J.P. Heterogeneity in the protein cores of mucins isolated from human middle ear effusions: evidence for expression of different mucin gene products. Glycoconj. J. 15:1998;283-291.
15. Lopez-Ferrer A., Curull V., Barranco C., Garrido M., Lloreta J., Real F.X., et al. Mucins as differention markers in bronchial epithelium: squamous cell carcinoma and adenocarcinoma display similar expression patterns. Am. J. Respir. Cell Mol. Biol. 24:2001;22-29.
16. Lapensee L., Paquette Y., Bleau G. Allelic polymorphism and chromosomal localization of the human oviductin gene (MUC9). Fertil. Steril. 68:1997;702-708.
17. Li J.D., Feng W., Gallup M., Kim J.H., Gum J., Kim Y., et al. Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc. Natl. Acad. Sci. USA. 95:1998;5718-5723.
18. Lemjabbar H., Basbaum C. Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells. Nat. Med. 8:2002;41-46.