A balance of capping protein and profilin functions is required to regulate actin polymerization in Drosophila bristle

Molecular Biology of the Cell

Volumn 14, Issue 1, 2003, Pages 118-128

  Hopmann, Roberta ^a   Miller, Kathryn G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CAPPING PROTEIN; PROFILIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CELLULAR DISTRIBUTION; CYTOSKELETON; DROSOPHILA; GENE MUTATION; GENE OVEREXPRESSION; NONHUMAN; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SCANNING ELECTRON MICROSCOPY;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; CONTRACTILE PROTEINS; DESTRIN; DROSOPHILA; DROSOPHILA PROTEINS; HETEROZYGOTE; MICROFILAMENT PROTEINS; PHENOTYPE; PROFILINS;

HEXAPODA;

EID: 0037237825     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-05-0300     Document Type: Article

References (37)

1. Appel, L.F., Prout, M., Abu-Shumays, R., Hammonds, A., Garbe, J.C., Fristrom, D., and Fristrom, J. (1993). The Drosophila Stubblestubbloid gene encodes an apparent transmembrane serine protease required for epithelial morphogenesis. Proc. Natl. Acad. Sci. USA 90, 4937-4941.
2. Benlali, A., Draskovic, I., Hazelett, D.J., and Treisman, J.E. (2000). Act up controls actin polymerization to alter cell shape and restrict Hedgehog signaling in the Drosophila eye disc. Cell 101, 271-281.
3. Blanchoin, L., and Pollard, T.D. (1998). Interaction of actin monomers with Acanthamoeba actophorin (ADF/cofilin) and profilin. J. Biol. Chem. 273, 25106-25111.
4. Boquet, I., R. Boujemaaa, M. F. Carlier and T. Preat (2000). Ciboulot regulates actin assembly during Drosophila brain metamorphosis. Cell 102, 797-808.
5. Carlsson, L., Nystrom, L.E., Sundkvist, I., Markey, F., and Lindberg, U. (1977). Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells. J. Mol. Biol. 115, 465-483.
6. Casella, J.F., Maack, D.J., and Lin, S. (1986). Purification and initial characterization of a protein from skeletal muscle that caps the barbed ends of actin filaments. J. Biol. Chem. 261, 10915-10921.
7. Chen, J., Godt, D., Gunsalus, K., Kiss, I., Goldberg, M., and Laski, F.A. (2001). Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis. Nat. Cell Biol. 3, 204-209.
8. Didry, D., Carlier, M.-F., and Pantaloni, D. (1998). Synergy between actin depolymerizing factor/cofilin and profilin in increasing actin filament turnover. J. Biol. Chem. 273, 25602-25611.
9. Eads, J.C., Mahoney, N.M., Vorobiev, S., Bresnick, A.R., Wen, K.K., Rubenstein, P.A., Haarer, B.K., and Almo, S.C. (1998). Structure determination and characterization of Saccharomyces cerevisiae profilin. Biochemistry 37, 11171-11181.
10. Finkel, T., J. A. Theriot, K. R. Dise, G. F. Tomaselli and P. J. Goldschmidt-Clermont (1994). Dynamic actin structures stabilized by profilin. Proc Natl Acad Sci USA 91, 1510-1514.
11. Guild, G.M., Connelly, P.S., Vranich, K.A., Shaw, M.K., and Tilney, L.G. (2002). Actin filament turnover removes bundles from Drosophila bristle cells. J. Cell Sci. 115, 641-653.
12. Gunsalus, K.C., Bonaccorsi, S., Williams, E., Verni, F., Gatti, M., and Goldberg, M.L. (1995). Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis. J. Cell Biol. 131, 1243-1259.
13. Hopmann, R., Cooper, J.A., and Miller, K.G. (1996). Actin organization, bristle morphology, and viability are affected by actin capping protein mutations in Drosophila. J. Cell Biol. 133, 1293-1305.
14. Isenberg, G., Aebi, U., and Pollard, T.D. (1980). An actin-binding protein from Acanthamoeba regulates actin filament polymerization and interactions. Nature 288, 455-459.
15. Kang, F., Purich, D.L., and Southwick, F.S. (1999). Profilin promotes barbed-end actin filament assembly without lowering the critical concentration. J. Biol. Chem. 274, 36963-36972.
16. Kovar, D.R., Yang, P., Sale, W.S., Drobak, B.K., and Staiger, C.J. (2001) Chlamydomonas reinhardtii produces a profilin with unusual biochemical properties. J. Cell Sci. 114, 4293-4305.
17. Lee, T., and Luo, L. (2001). Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci. 24, 251-254.
18. Lewis, E.B. (1960). A new standard food medium. Drosoph. Inf. Serv. 34, 117-118.
19. Lu, J., and Pollard, T.D. (2001). Profilin binding to poly-L-proline and actin monomers along with ability to catalyze actin nucleotide exchange is required for viability of fission yeast. Mol. Biol. Cell 12, 1161-1175.
20. Luo, L., Lee, T., Nardine, T., Null, B., and Reuter, J. (1999). Using the MARCM system to positively mark mosaic clones in Drosophila. Drosoph. Inf. Serv. 82, 102-105.
21. Niwa, R., Nagata-Ohashi, K., Takeichi, M., Mizuno, K., and Uemura, T. (2002). Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell 108, 233-246.
22. Overton, J. (1967). The fine structure of developing bristles in wild type and mutant Drosophila melanogaster. J. Morphol. 122, 367-379.
23. Palmgren, S., Ojala, P.J., Wear, M.A., Cooper, J.A., and Lappalainen, P. (2001). Interactions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin. J. Cell Biol. 155, 251-260.
24. Palmgren, S., Vartiainen, M., and Lappalainen, P. (2002). Twinfilin, a molecular mailman for actin monomers. J. Cell Sci. 115, 881-886.
25. Pantaloni, D., and Carlier, M.F. (1993). How profilin promotes actin filament assembly in the presence of thymosin beta 4. Cell 75, 1007-1014.
26. Perelroizen, I., Didry, D., Christensen, H., Chua, N.H., and Carlier, M.F. (1996). Role of nucleotide exchange and hydrolysis in the function of profilin in action assembly. J. Biol. Chem. 271, 12302-12309.
27. Pollard, T. (1986). Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments. J. Cell Biol. 103, 2747-2754.
28. Pollard, T.D., and Cooper, J.A. (1984). Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation. Biochemistry 23, 6631-6641.
29. Pollard, T.D., Blanchoin, L., and Mullins, R.D. (2000). Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu. Rev. Biophys. Biomol. Struct. 29, 545-576.
30. Rothkegel, M., O. Mayboroda, M. Rohde, C. Wucherpfennig, R. Valenta and B.M. Jockusch (1996). Plant and animal profilins are functionally equivalent and stabilize microfilaments in living animal cells. J Cell Sci 109, 83-90.
31. Schafer, D.A., Hug, C., and Cooper, J.A. (1995). Inhibition of CapZ during myofibrillogenesis alters assembly of actin filaments. J. Cell Biol. 128, 61-70.
32. Tilney, L.G., Connelly, P.S., Vranich, K.A., Shaw, M.K., and Guild, G.M. (1998). Why are two different cross-linkers necessary for actin bundle formation in vivo and what does each cross-link contribute? J. Cell Biol. 143, 121-133.
33. Tilney, L., Connelly, P., Vranich, K., Shaw, M., and Guild, G. (2000a). Actin filaments and microtubules play different roles during bristle elongation in Drosophila. J. Cell Sci. 113, 1255-1265.
34. Tilney, L.G., Connelly, P.S., Vranich, K.A., Shaw, M.K., and Guild, G.M. (2000b). Regulation of actin filament cross-linking and bundle shape in Drosophila bristles. J. Cell Biol. 148, 87-100.
35. Verheyen, E.M., and Cooley, L. (1994). Profilin mutations disrupt multiple actin-dependent processes during Drosophila development. Development 120, 717-728.
36. Wahlstrom, G., Vartiainen, M., Yamamoto, L., Mattila, P.K., Lappalainen, P., and Heino, T.I. (2001). Twinfilin is required for actin-dependent developmental processes in Drosophila. J. Cell Biol. 155, 787-796.
37. Wolven, A.K., Belmont, L.D., Mahoney, N.M., Almo, S.C., and Drubin, D.G. (2000). In vivo importance of actin nucleotide exchange catalyzed by profilin. J. Cell Biol. 150, 895-904.