메뉴 건너뛰기




Volumn 88, Issue 1, 2003, Pages 71-74

Is there a role for treatment of asthma with omalizumab?

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; BRONCHODILATING AGENT; CORTICOSTEROID; FC RECEPTOR; IMMUNOGLOBULIN E; NEDOCROMIL; OMALIZUMAB;

EID: 0037235317     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.88.1.71     Document Type: Review
Times cited : (14)

References (55)
  • 1
    • 0032881562 scopus 로고    scopus 로고
    • Prevalence and severity of asthma, rhinitis, and atopic eczema: The north east study
    • Shamssain MH, Shamsian N. Prevalence and severity of asthma, rhinitis, and atopic eczema: the north east study. Arch Dis Child 1999;81:313-17.
    • (1999) Arch Dis Child , vol.81 , pp. 313-317
    • Shamssain, M.H.1    Shamsian, N.2
  • 2
    • 0032501657 scopus 로고    scopus 로고
    • Prevalence of asthma symptoms, diagnosis, and treatment in 12-14 year old children across Great Britain (international study of asthma and allergies in childhood, ISAAC UK)
    • Kaur B, Anderson HR, Austin J, et al. Prevalence of asthma symptoms, diagnosis, and treatment in 12-14 year old children across Great Britain (international study of asthma and allergies in childhood, ISAAC UK). BMJ 1998;316:118-24.
    • (1998) BMJ , vol.316 , pp. 118-124
    • Kaur, B.1    Anderson, H.R.2    Austin, J.3
  • 3
    • 0344718441 scopus 로고    scopus 로고
    • Changing prevalence of allergic rhinitis and asthma
    • quiz 248-52
    • Sly RM. Changing prevalence of allergic rhinitis and asthma. Ann Allergy Asthma Immunol 1999;82:233-48, quiz 248-52.
    • (1999) Ann Allergy Asthma Immunol , vol.82 , pp. 233-248
    • Sly, R.M.1
  • 4
    • 0033846983 scopus 로고    scopus 로고
    • Decreases in asthma mortality in the United States
    • Sly RM. Decreases in asthma mortality in the United States. Ann Allergy Asthma Immunol 2000;85:121-7.
    • (2000) Ann Allergy Asthma Immunol , vol.85 , pp. 121-127
    • Sly, R.M.1
  • 5
    • 0026872922 scopus 로고
    • Pediatric asthma deaths in Victoria: The mild are at risk
    • Robertson CF, Rubinfeld AR, Bowes G. Pediatric asthma deaths in Victoria: the mild are at risk. Pediatr Pulmonol 1992;13:95-100.
    • (1992) Pediatr Pulmonol , vol.13 , pp. 95-100
    • Robertson, C.F.1    Rubinfeld, A.R.2    Bowes, G.3
  • 6
    • 0012620672 scopus 로고    scopus 로고
    • Drug treatment of wheezy infants
    • David T, ed. London: Churchill Livingstone
    • Milgrom H. Drug treatment of wheezy infants. In: David T, ed. Recent advances in paediatrics. London: Churchill Livingstone, 2001:27-42.
    • (2001) Recent Advances in Paediatrics , pp. 27-42
    • Milgrom, H.1
  • 7
    • 0035188806 scopus 로고    scopus 로고
    • The pattern of atopic sensitization is associated with the development of asthma in childhood
    • Illi S, von Mutius E, Lau S, et al. The pattern of atopic sensitization is associated with the development of asthma in childhood. J Allergy Clin Immunol 2001;108:709-14.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 709-714
    • Illi, S.1    Von Mutius, E.2    Lau, S.3
  • 8
    • 0034895060 scopus 로고    scopus 로고
    • Asthma in preschool children: Prevalence and risk factors
    • Haby MM, Peat JK, Marks GB, et al. Asthma in preschool children: prevalence and risk factors. Thorax 2001;56:589-95.
    • (2001) Thorax , vol.56 , pp. 589-595
    • Haby, M.M.1    Peat, J.K.2    Marks, G.B.3
  • 9
    • 0035188697 scopus 로고    scopus 로고
    • Early life risk factors for adult asthma: A birth cohort study of subjects at risk
    • Rhodes HL, Sporik R, Thomas P, et al. Early life risk factors for adult asthma: a birth cohort study of subjects at risk. J Allergy Clin Immunol 2001;108:720-5.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 720-725
    • Rhodes, H.L.1    Sporik, R.2    Thomas, P.3
  • 10
    • 0033604657 scopus 로고    scopus 로고
    • The role of allergy in the development of asthma
    • Holt PG, Macaubas C, Stumbles PA, et al. The role of allergy in the development of asthma. Nature 1999;402(6760 suppl):B12-17.
    • (1999) Nature , vol.402 , Issue.6760 SUPPL.
    • Holt, P.G.1    Macaubas, C.2    Stumbles, P.A.3
  • 11
    • 0033495763 scopus 로고    scopus 로고
    • Present and future treatment of asthma in infants and young children
    • Martinez FD. Present and future treatment of asthma in infants and young children. J Allergy Clin Immunol 1999;104(4 pt 2):169-74.
    • (1999) J Allergy Clin Immunol , vol.104 , Issue.4 PART 2 , pp. 169-174
    • Martinez, F.D.1
  • 12
    • 0030664979 scopus 로고    scopus 로고
    • Choosing therapy for childhood asthma
    • Holgate ST, Frew AJ. Choosing therapy for childhood asthma. N Engl J Med 1997;337:1690-2.
    • (1997) N Engl J Med , vol.337 , pp. 1690-1692
    • Holgate, S.T.1    Frew, A.J.2
  • 14
    • 0030981457 scopus 로고    scopus 로고
    • Airway wall remodelling in asthma
    • Redington AE, Howarth PH. Airway wall remodelling in asthma. Thorax 1997;52:310-12.
    • (1997) Thorax , vol.52 , pp. 310-312
    • Redington, A.E.1    Howarth, P.H.2
  • 15
    • 0034784589 scopus 로고    scopus 로고
    • Early environmental influences in the development of asthma and atopic disease
    • Helms PJ. Early environmental influences in the development of asthma and atopic disease. Monaldi Arch Chest Dis 2001;56:265-9.
    • (2001) Monaldi Arch Chest Dis , vol.56 , pp. 265-269
    • Helms, P.J.1
  • 18
    • 0031034624 scopus 로고    scopus 로고
    • The British guidelines on asthma management: 1995 Review and position statement
    • British Thoracic Society. The British guidelines on asthma management: 1995 review and position statement. Thorax 1997;52:S1-21.
    • (1997) Thorax , vol.52
  • 19
    • 0031915033 scopus 로고    scopus 로고
    • Third International Pediatric Consensus statement on the management of childhood asthma
    • International Pediatric Asthma Consensus Group
    • Warner JO, Naspitz CK. Third International Pediatric Consensus statement on the management of childhood asthma. International Pediatric Asthma Consensus Group. Pediatr Pulmonol 1998;25:1-17.
    • (1998) Pediatr Pulmonol , vol.25 , pp. 1-17
    • Warner, J.O.1    Naspitz, C.K.2
  • 20
    • 0030859592 scopus 로고    scopus 로고
    • Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood
    • Stein RT, Holberg CJ, Morgan WJ, et al. Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood. Thorax 1997;52:946-52.
    • (1997) Thorax , vol.52 , pp. 946-952
    • Stein, R.T.1    Holberg, C.J.2    Morgan, W.J.3
  • 21
    • 0035804276 scopus 로고    scopus 로고
    • Allergy and allergic diseases. First of two parts
    • Kay AB. Allergy and allergic diseases. First of two parts. N Engl J Med 2001;344:30-7.
    • (2001) N Engl J Med , vol.344 , pp. 30-37
    • Kay, A.B.1
  • 22
    • 0024417007 scopus 로고
    • The subclass of IgG antibody in allergic disease: II. The IgG subclass of antibodies produced following natural exposure to dust mite and grass pollen in atopic and non-atopic individuals
    • Kemeny DM, Urbanek R, Ewan P, et al. The subclass of IgG antibody in allergic disease: II. The IgG subclass of antibodies produced following natural exposure to dust mite and grass pollen in atopic and non-atopic individuals. Clin Exp Allergy 1989;19:545-9.
    • (1989) Clin Exp Allergy , vol.19 , pp. 545-549
    • Kemeny, D.M.1    Urbanek, R.2    Ewan, P.3
  • 23
    • 0025923025 scopus 로고
    • Human TH1 and TH2 subsets: Doubt no more
    • Romagnani S. Human TH1 and TH2 subsets: doubt no more. Immunol Today 1991;12:256-7.
    • (1991) Immunol Today , vol.12 , pp. 256-257
    • Romagnani, S.1
  • 24
    • 0028873098 scopus 로고
    • Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients
    • Ebner C, Schenk S, Najafian N, et al. Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients. J Immunol 1995; 154:1932-40.
    • (1995) J Immunol , vol.154 , pp. 1932-1940
    • Ebner, C.1    Schenk, S.2    Najafian, N.3
  • 25
    • 0030897526 scopus 로고    scopus 로고
    • IL-13 production by allergen-stimulated T cells is increased in allergic disease and associated with IL-5 but not IFN-gamma expression
    • Till S, Durham S, Dickason R, et al. IL-13 production by allergen-stimulated T cells is increased in allergic disease and associated with IL-5 but not IFN-gamma expression. Immunology 1997;91:53-7.
    • (1997) Immunology , vol.91 , pp. 53-57
    • Till, S.1    Durham, S.2    Dickason, R.3
  • 27
    • 0028432821 scopus 로고
    • Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: Evidence for the human mast cell as a saurce of these cytokines
    • Bradding P, Roberts JA, Britten KM, et al. Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a saurce of these cytokines. Am J Respir Cell Mol Biol 1994;10:471-80.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 471-480
    • Bradding, P.1    Roberts, J.A.2    Britten, K.M.3
  • 28
    • 0028863602 scopus 로고
    • Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis
    • Pawankar RU, Okuda M, Hasegawa S, et al. Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis. Am J Respir Crit Care Med 1995;152(6 pt 1):2059-67.
    • (1995) Am J Respir Crit Care Med , vol.152 , Issue.6 PART 1 , pp. 2059-2067
    • Pawankar, R.U.1    Okuda, M.2    Hasegawa, S.3
  • 29
    • 0032699213 scopus 로고    scopus 로고
    • IgE in asthma and atopy: Cellular and molecular connections
    • Oettgen HC, Geha RS. IgE in asthma and atopy: cellular and molecular connections. J Clin Invest 1999;104:829-35.
    • (1999) J Clin Invest , vol.104 , pp. 829-835
    • Oettgen, H.C.1    Geha, R.S.2
  • 30
    • 0031911613 scopus 로고    scopus 로고
    • High-affinity immunoglobulin E receptor (Fc epsilon RI)-bearing eosinophils, mast cells, macrophages and Langerhans' cells in allergen- induced late-phase cutaneous reactions in atopic subjects
    • Ying S, Barata LT, Meng Q, et al. High-affinity immunoglobulin E receptor (Fc epsilon RI)-bearing eosinophils, mast cells, macrophages and Langerhans' cells in allergen- induced late-phase cutaneous reactions in atopic subjects. Immunology 1998;93:281-8.
    • (1998) Immunology , vol.93 , pp. 281-288
    • Ying, S.1    Barata, L.T.2    Meng, Q.3
  • 31
    • 0030920880 scopus 로고    scopus 로고
    • Expression of high-affinity IgE receptors (Fc epsilon RI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations
    • Sihra BS, Kon OM, Grant JA, et al. Expression of high-affinity IgE receptors (Fc epsilon RI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: relationship to total serum IgE concentrations. J Allergy Clin Immunol 1997;99:699-706.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 699-706
    • Sihra, B.S.1    Kon, O.M.2    Grant, J.A.3
  • 32
    • 0030837924 scopus 로고    scopus 로고
    • Enhanced expression of high-affinity IgE receptor (Fc epsilon RI) alpha chain in human allergen-induced rhinitis with co-localization to mast cells, macrophages, eosinophils, and dendritic cells
    • Rajakulasingam K, Durham SR, O'Brien F, et al. Enhanced expression of high-affinity IgE receptor (Fc epsilon RI) alpha chain in human allergen-induced rhinitis with co-localization to mast cells, macrophages, eosinophils, and dendritic cells. J Allergy Clin Immunol 1997;100:78-86.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 78-86
    • Rajakulasingam, K.1    Durham, S.R.2    O'Brien, F.3
  • 33
    • 0024246935 scopus 로고
    • Functional interaction between B cell subpopulations defined by CD23 expression
    • Armitage RJ, Goff LK. Functional interaction between B cell subpopulations defined by CD23 expression. Eur J Immunol 1988;18:1753-60.
    • (1988) Eur J Immunol , vol.18 , pp. 1753-1760
    • Armitage, R.J.1    Goff, L.K.2
  • 34
    • 0031720045 scopus 로고    scopus 로고
    • Molecular concepts of IgE-initiated inflammation in atopic and nonatopic asthma
    • Menz G, Ying S, Durham SR, et al. Molecular concepts of IgE-initiated inflammation in atopic and nonatopic asthma. Allergy 1998;53:15-21.
    • (1998) Allergy , vol.53 , pp. 15-21
    • Menz, G.1    Ying, S.2    Durham, S.R.3
  • 35
    • 0027366769 scopus 로고
    • Cessation of long-term treatment with inhaled corticosteroid (budesonide) in children with asthma results in deterioration
    • The Dutch CNSLD Study Group
    • Waalkens HJ, Van Essen-Zandvliet EE, Hughes MD, et al. Cessation of long-term treatment with inhaled corticosteroid (budesonide) in children with asthma results in deterioration. The Dutch CNSLD Study Group. Am Rev Respir Dis 1993;148:1252-7.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1252-1257
    • Waalkens, H.J.1    Van Essen-Zandvliet, E.E.2    Hughes, M.D.3
  • 36
    • 0028315946 scopus 로고
    • Remission of childhood asthma after long-term treatment with an inhaled corticosteroid (budesonide): Can it be achieved?
    • Dutch CNSLD Study Group
    • van Essen-Zandvliet EE, Hughes MD, Waalkens HJ, et al. Remission of childhood asthma after long-term treatment with an inhaled corticosteroid (budesonide): can it be achieved? Dutch CNSLD Study Group. Eur Respir J 1994;7:63-8.
    • (1994) Eur Respir J , vol.7 , pp. 63-68
    • Van Essen-Zandvliet, E.E.1    Hughes, M.D.2    Waalkens, H.J.3
  • 37
    • 0032733699 scopus 로고    scopus 로고
    • Nonreversible airflow obstruction in life-long nonsmokers with moderate to severe asthma
    • Ulrik CS, Backer V. Nonreversible airflow obstruction in life-long nonsmokers with moderate to severe asthma. Eur Respir J 1999;14:892-6.
    • (1999) Eur Respir J , vol.14 , pp. 892-896
    • Ulrik, C.S.1    Backer, V.2
  • 38
    • 0034642066 scopus 로고    scopus 로고
    • Long-term effects of budesonide or nedocromil in children with asthma
    • The Childhood Asthma Management Program Research Group. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med 2000;343:1054-63.
    • (2000) N Engl J Med , vol.343 , pp. 1054-1063
  • 39
    • 0033925648 scopus 로고    scopus 로고
    • Prevention of adult asthma by early intervention during childhood: Potential value of new generation immunomodulatory drugs
    • Holt PG, Sly PD. Prevention of adult asthma by early intervention during childhood: potential value of new generation immunomodulatory drugs. Thorax 2000;55:700-3.
    • (2000) Thorax , vol.55 , pp. 700-703
    • Holt, P.G.1    Sly, P.D.2
  • 41
    • 0030956903 scopus 로고    scopus 로고
    • The effect of an anti-IgE monoclonal antibody on the early and late phase responses to allergen inhalation in asthmatic subjects
    • Fahy J, Fleming H, Wong H, et al. The effect of an anti-IgE monoclonal antibody on the early and late phase responses to allergen inhalation in asthmatic subjects. Am J Respir Crit Care Med 1997;155:1828-34.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1828-1834
    • Fahy, J.1    Fleming, H.2    Wong, H.3
  • 42
    • 0028143496 scopus 로고
    • The binding site on human immunoglobulin E for its high affinity receptor
    • Presta L, Gorman C, Shields R, et al. The binding site on human immunoglobulin E for its high affinity receptor. J Biol Chem 1994;269:26368-73.
    • (1994) J Biol Chem , vol.269 , pp. 26368-26373
    • Presta, L.1    Gorman, C.2    Shields, R.3
  • 43
    • 0031065108 scopus 로고    scopus 로고
    • Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody
    • MacGlashan DW Jr, Bochner BS, Adelman DC, et al. Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. J Immunol 1997;158:1438-45.
    • (1997) J Immunol , vol.158 , pp. 1438-1445
    • MacGlashan D.W., Jr.1    Bochner, B.S.2    Adelman, D.C.3
  • 44
    • 0000898623 scopus 로고    scopus 로고
    • The pharmacological basis of anti-IgE therapy
    • Chang TW. The pharmacological basis of anti-IgE therapy. Nat Biotechnol 2000;18:157-62.
    • (2000) Nat Biotechnol , vol.18 , pp. 157-162
    • Chang, T.W.1
  • 45
    • 0036369962 scopus 로고    scopus 로고
    • Attainments in atopy: Special aspects of allergy and IgE
    • In press
    • Milgrom H. Attainments in atopy: special aspects of allergy and IgE. Adv Pediatr. In press.
    • Adv Pediatr
    • Milgrom, H.1
  • 46
    • 8244226656 scopus 로고    scopus 로고
    • Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response
    • Boulet L, Chapman K, Cote J, et al. Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response. Am J Respir Crit Care Med 1997;155:1835-40.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1835-1840
    • Boulet, L.1    Chapman, K.2    Cote, J.3
  • 47
    • 0033599043 scopus 로고    scopus 로고
    • Treatment of allergic asthma with monoclonal anti-IgE antibody
    • rhuMAb- E25 Study Group
    • Milgrom H, Fick RB Jr, Su JQ, et al. Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb- E25 Study Group. N Engl J Med 1999;341:1966-73.
    • (1999) N Engl J Med , vol.341 , pp. 1966-1973
    • Milgrom, H.1    Fick R.B., Jr.2    Su, J.Q.3
  • 48
    • 0034907372 scopus 로고    scopus 로고
    • Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
    • Busse W, Corren J, Lanier BQ, et al. Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. J Allergy Clin Immunol 2001;108:184-90.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 184-190
    • Busse, W.1    Corren, J.2    Lanier, B.Q.3
  • 49
    • 0034881877 scopus 로고    scopus 로고
    • The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
    • Soler M, Matz J, Townley R, et al. The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. Eur Respir J 2001;18:254-61.
    • (2001) Eur Respir J , vol.18 , pp. 254-261
    • Soler, M.1    Matz, J.2    Townley, R.3
  • 50
    • 0035434688 scopus 로고    scopus 로고
    • Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab)
    • Milgrom H, Berger W, Nayak A, et al. Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab). Pediatrics 2001;108:E36.
    • (2001) Pediatrics , vol.108
    • Milgrom, H.1    Berger, W.2    Nayak, A.3
  • 51
    • 0033836319 scopus 로고    scopus 로고
    • Recombinant humanized mAb-E25 an anti-IgE mAb, in birch pollen-induced seasonal allergic rhinitis
    • Adelroth E, Rak S, Haahtela T, et al. Recombinant humanized mAb-E25 an anti-IgE mAb, in birch pollen-induced seasonal allergic rhinitis. J Allergy Clin Immunol 2000;106:253-9.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 253-259
    • Adelroth, E.1    Rak, S.2    Haahtela, T.3
  • 52
    • 0035915364 scopus 로고    scopus 로고
    • Effect of omalizumab on symptoms of seasonal allergic rhinitis: A randomized controlled trial
    • Casale TB, Condemi J, LaForce C, et al. Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial. JAMA 2001;286:2956-67.
    • (2001) JAMA , vol.286 , pp. 2956-2967
    • Casale, T.B.1    Condemi, J.2    LaForce, C.3
  • 53
    • 0035049370 scopus 로고    scopus 로고
    • Invited lecture: Activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma
    • Holgate ST, Lackie PM, Howarth PH, et al. Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma. Int Arch Allergy Immunol 2001;124:253-8.
    • (2001) Int Arch Allergy Immunol , vol.124 , pp. 253-258
    • Holgate, S.T.1    Lackie, P.M.2    Howarth, P.H.3
  • 54
    • 0028079557 scopus 로고
    • Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy
    • Sher ER, Leung DY, Surs W, et al. Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest 1994;93:33-9.
    • (1994) J Clin Invest , vol.93 , pp. 33-39
    • Sher, E.R.1    Leung, D.Y.2    Surs, W.3
  • 55
    • 0030457409 scopus 로고    scopus 로고
    • Non-compliance and treatment failure in children with asthma
    • Milgrom H, Bender B, Ackerson L, et al. Non-compliance and treatment failure in children with asthma. J Allergy Clin Immunol 1996;98:1051-7.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 1051-1057
    • Milgrom, H.1    Bender, B.2    Ackerson, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.