-
1
-
-
0029902007
-
Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer
-
Kemp G, Rose P, Lurain J et al.: Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer. J Clin Oncol 14: 2101-2112, 1996.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2101-2112
-
-
Kemp, G.1
Rose, P.2
Lurain, J.3
-
2
-
-
0031840023
-
Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer
-
Buntzel J, Kuttner K, Frohlich D and Glatzel M: Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer [see comments]. Ann Oncol 9: 505-509, 1998.
-
(1998)
Ann Oncol
, vol.9
, pp. 505-509
-
-
Buntzel, J.1
Kuttner, K.2
Frohlich, D.3
Glatzel, M.4
-
3
-
-
0023679159
-
Uptake of WR-2721 derivatives by cells in culture: Identification of the transported form of the drug
-
Calabro-Jones PM, Aguilera JA, Ward JF, Smoluk GD and Fahey RC: Uptake of WR-2721 derivatives by cells in culture: identification of the transported form of the drug. Cancer Res 48: 3634-3640, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 3634-3640
-
-
Calabro-Jones, P.M.1
Aguilera, J.A.2
Ward, J.F.3
Smoluk, G.D.4
Fahey, R.C.5
-
4
-
-
0023793476
-
Radioprotection of cells in culture by WR-2721 and derivatives: Form of the drug responsible for protection
-
Smoluk GD, Fahey RC, Calabro-Jones PM, Aguilera JA and Ward JF: Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection. Cancer Res 48: 3641-3647, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 3641-3647
-
-
Smoluk, G.D.1
Fahey, R.C.2
Calabro-Jones, P.M.3
Aguilera, J.A.4
Ward, J.F.5
-
5
-
-
0029745368
-
Amifostine: The preclinical basis for broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies
-
Capizzi R: Amifostine: the preclinical basis for broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies. Semin Oncol 23: 2-17, 1996.
-
(1996)
Semin Oncol
, vol.23
, pp. 2-17
-
-
Capizzi, R.1
-
6
-
-
0032951293
-
Effects of amifostine on perfused isolated rat heart and on acute doxorubicin-induced cardiotoxicity
-
Nazeyrollas P, Prevost A, Baccard N, Manot L, Devillier P and Millart H: Effects of amifostine on perfused isolated rat heart and on acute doxorubicin-induced cardiotoxicity. Cancer Chemother Pharmacol 43: 227-232, 1999.
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, pp. 227-232
-
-
Nazeyrollas, P.1
Prevost, A.2
Baccard, N.3
Manot, L.4
Devillier, P.5
Millart, H.6
-
7
-
-
0029906872
-
Cardioprotection of rat heart myocytes with amifostine (Ethyol) and its free thiol, WR-1065, in vitro
-
Dorr RT, Lagel K and McLean S: Cardioprotection of rat heart myocytes with amifostine (Ethyol) and its free thiol, WR-1065, in vitro. Eur J Cancer 32A: Suppl 4: S21-5, 1996.
-
(1996)
Eur J Cancer
, vol.32 A
, Issue.SUPPL. 4
-
-
Dorr, R.T.1
Lagel, K.2
McLean, S.3
-
8
-
-
0025948220
-
The chemical reactivity of the modulating agent WR2721 (ethiofos) and its main metabolites with the antitumor agents cisplatin and carboplatin
-
Treskes M, Holwerda U, Klein I, Pinedo HM and van der Viigh WJ: The chemical reactivity of the modulating agent WR2721 (ethiofos) and its main metabolites with the antitumor agents cisplatin and carboplatin. Biochemical Pharmacology 42: 2125-2130, 1991.
-
(1991)
Biochemical Pharmacology
, vol.42
, pp. 2125-2130
-
-
Treskes, M.1
Holwerda, U.2
Klein, I.3
Pinedo, H.M.4
Van der Viigh, W.J.5
-
9
-
-
0026588374
-
N-(2-mercaptoethyl)-1,3 propanediamine (WR-1065) protects thymocytes from programmed cell death
-
Ramakrishnan N and Catraves GN: N-(2-mercaptoethyl)-1,3 propanediamine (WR-1065) protects thymocytes from programmed cell death. J Immunol 148: 817, 1992.
-
(1992)
J Immunol
, vol.148
, pp. 817
-
-
Ramakrishnan, N.1
Catraves, G.N.2
-
10
-
-
0344309515
-
Development of the model of rat isolated perfused heart for the evaluation of anthracycline cardiotoxicity and its circumvention
-
Pouna P, Bonoron-Adele S, Gouverneur G, Tariosse L, Besse P and Robert J: Development of the model of rat isolated perfused heart for the evaluation of anthracycline cardiotoxicity and its circumvention. Br J Pharmacol 117: 1593-1599, 1996.
-
(1996)
Br J Pharmacol
, vol.117
, pp. 1593-1599
-
-
Pouna, P.1
Bonoron-Adele, S.2
Gouverneur, G.3
Tariosse, L.4
Besse, P.5
Robert, J.6
-
11
-
-
0034016426
-
Comparison of the protective effects of amifostine and dexrazoxane against the toxicity of doxorubicin in spontaneously hypertensive rats
-
Herman EH, Zhang J, Chadwick DP and Ferrans VJ: Comparison of the protective effects of amifostine and dexrazoxane against the toxicity of doxorubicin in spontaneously hypertensive rats. Cancer Chemother Pharmacol 45: 329-334, 2000.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 329-334
-
-
Herman, E.H.1
Zhang, J.2
Chadwick, D.P.3
Ferrans, V.J.4
-
12
-
-
0014903119
-
Biological factors affecting the radioprotective efficiency of S-2-[2-aminopropylamino] ethylphosphorothioic acid (WR-2721). LD50(3)) doses
-
Yuhas JM: Biological factors affecting the radioprotective efficiency of S-2-[2-aminopropylamino] ethylphosphorothioic acid (WR-2721). LD50(3)) doses. Radiat Res 44: 621-628, 1970.
-
(1970)
Radiat Res
, vol.44
, pp. 621-628
-
-
Yuhas, J.M.1
-
13
-
-
0026666570
-
Biochemical modification of the toxicity and the anti-tumour effect of 5-fluorouracil and cis-platinum by WR-2721 in mice
-
van der Wilt CL, van Laar JA, Gyergyay F, Smid K and Peters GJ: Biochemical modification of the toxicity and the anti-tumour effect of 5-fluorouracil and cis-platinum by WR-2721 in mice. Eur J Cancer 28A: 2017-2024, 1992.
-
(1992)
Eur J Cancer
, vol.28 A
, pp. 2017-2024
-
-
Van der Wilt, C.L.1
Van Laar, J.A.2
Gyergyay, F.3
Smid, K.4
Peters, G.J.5
-
14
-
-
0029743272
-
Effects of amifostine and paclitaxel on growth of human ovarian carcinoma xenografts in the severe combined immune-deficient mouse: Preliminary results
-
Paine GD, Taylor CW, Lopez MH, Johnson CS and Capizzi RL: Effects of amifostine and paclitaxel on growth of human ovarian carcinoma xenografts in the severe combined immune-deficient mouse: preliminary results. Semin Oncol 23: 35-39, 1996.
-
(1996)
Semin Oncol
, vol.23
, pp. 35-39
-
-
Paine, G.D.1
Taylor, C.W.2
Lopez, M.H.3
Johnson, C.S.4
Capizzi, R.L.5
-
15
-
-
0034161542
-
Patients with myelodysplastic syndromes benefit from palliative therapy with amifostine, pentoxifylline, and ciprofloxacin with or without dexamethasone
-
Raza A, Qawi H, Lisak L et al.: Patients with myelodysplastic syndromes benefit from palliative therapy with amifostine, pentoxifylline, and ciprofloxacin with or without dexamethasone. Blood 95: 1580-1587, 2000.
-
(2000)
Blood
, vol.95
, pp. 1580-1587
-
-
Raza, A.1
Qawi, H.2
Lisak, L.3
-
16
-
-
0029091758
-
A phase I trial of amifostine (WR-2721) and melphalan in children with refractory cancer
-
Adamson PC, Balis FM, Belasco JE et al.: A phase I trial of amifostine (WR-2721) and melphalan in children with refractory cancer. Cancer Res 55: 4069-4072, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 4069-4072
-
-
Adamson, P.C.1
Balis, F.M.2
Belasco, J.E.3
-
17
-
-
0017686259
-
Adriamycin-induced cardiotoxicity (cardiomyopathy and congestive heart failure) in rats
-
Mettler CE, Young DM and Ward JM: Adriamycin-induced cardiotoxicity (cardiomyopathy and congestive heart failure) in rats. Cancer Res 37: 2705-2713, 1977.
-
(1977)
Cancer Res
, vol.37
, pp. 2705-2713
-
-
Mettler, C.E.1
Young, D.M.2
Ward, J.M.3
-
18
-
-
0028228451
-
Early incidence of adriamycin treatment on cardiac parameters in the rat
-
Cottin Y, Ribuot C, Maupoil V et al.: Early incidence of adriamycin treatment on cardiac parameters in the rat. Can J Physiol Pharmacol 72: 140-145, 1994.
-
(1994)
Can J Physiol Pharmacol
, vol.72
, pp. 140-145
-
-
Cottin, Y.1
Ribuot, C.2
Maupoil, V.3
-
19
-
-
0029019896
-
Cardioprotective potency of the radical scavenger S-2-(3 aminopropylamino) ethylphosphorothioic acid in the post-ischaemic rat heart
-
Pissarek M, Janichen F, Blasig IE et al.: Cardioprotective potency of the radical scavenger S-2-(3 aminopropylamino) ethylphosphorothioic acid in the post-ischaemic rat heart. Mol Cell Biochem 145: 121-129, 1995.
-
(1995)
Mol Cell Biochem
, vol.145
, pp. 121-129
-
-
Pissarek, M.1
Janichen, F.2
Blasig, I.E.3
-
20
-
-
0026102728
-
Comparison of cytotoxicity in heart cells and tumor cells exposed to DNA intercalating agents in vitro
-
Dorr RT, Shipp NG and Lee KM: Comparison of cytotoxicity in heart cells and tumor cells exposed to DNA intercalating agents in vitro. Anticancer Drugs 2: 27-33, 1991.
-
(1991)
Anticancer Drugs
, vol.2
, pp. 27-33
-
-
Dorr, R.T.1
Shipp, N.G.2
Lee, K.M.3
-
21
-
-
0020684494
-
Effect of anthracycline antibiotics on oxygen radical formation in rat heart
-
Doroshow JH: Effect of anthracycline antibiotics on oxygen radical formation in rat heart. Cancer Res 43: 460-472, 1983.
-
(1983)
Cancer Res
, vol.43
, pp. 460-472
-
-
Doroshow, J.H.1
-
22
-
-
0027452020
-
Modulation of glutathione and glutathione dependent antioxidant enzymes in mouse heart following doxorubicin therapy
-
Gustafson DL, Swanson JD and Pritsos CA: Modulation of glutathione and glutathione dependent antioxidant enzymes in mouse heart following doxorubicin therapy. Free Radic Res Commun 19: 111-120, 1993.
-
(1993)
Free Radic Res Commun
, vol.19
, pp. 111-120
-
-
Gustafson, D.L.1
Swanson, J.D.2
Pritsos, C.A.3
-
23
-
-
0031714464
-
The role of iron in doxorubicin-induced cardiomyopathy
-
Myers C: The role of iron in doxorubicin-induced cardiomyopathy. Semin Oncol 25: 10-14, 1998.
-
(1998)
Semin Oncol
, vol.25
, pp. 10-14
-
-
Myers, C.1
-
24
-
-
0033950260
-
In vitro antioxidant properties of amifostine (WR-2721, Ethyol)
-
Marzatico F, Porta C, Moroni M et al.: In vitro antioxidant properties of amifostine (WR-2721, Ethyol). Cancer Chemother Pharmacol 45: 172-176, 2000.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 172-176
-
-
Marzatico, F.1
Porta, C.2
Moroni, M.3
-
25
-
-
0032005833
-
Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits
-
Arai M, Tomaru K, Takizawa T et al.: Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits. J Molec Cell Cardiol 30: 243-254, 1998.
-
(1998)
J Molec Cell Cardiol
, vol.30
, pp. 243-254
-
-
Arai, M.1
Tomaru, K.2
Takizawa, T.3
-
26
-
-
0033213550
-
Free oxygen radicals contribute to high incidence of reperfusion-induced arrhythmias in isolated rat heart
-
Ravingerova T, Slezak J, Tribulova N, Dzurba A, Uhrik B and Ziegelhoffer A: Free oxygen radicals contribute to high incidence of reperfusion-induced arrhythmias in isolated rat heart. Life Sci 65: 1927-1930, 1999.
-
(1999)
Life Sci
, vol.65
, pp. 1927-1930
-
-
Ravingerova, T.1
Slezak, J.2
Tribulova, N.3
Dzurba, A.4
Uhrik, B.5
Ziegelhoffer, A.6
-
27
-
-
0022412339
-
Effect of doxorubicin-enhanced hydrogen peroxide and hydroxyl radical formation on calcium sequestration by cardiac sarcoplasmic reticulum
-
Harris RN and Doroshow JH: Effect of doxorubicin-enhanced hydrogen peroxide and hydroxyl radical formation on calcium sequestration by cardiac sarcoplasmic reticulum. Biochem Biophys Res Commun 130: 739-745, 1985.
-
(1985)
Biochem Biophys Res Commun
, vol.130
, pp. 739-745
-
-
Harris, R.N.1
Doroshow, J.H.2
-
28
-
-
0024409541
-
Doxorubicin-induced calcium release from cardiac sarcoplasmic reticulum vesicles
-
Kim DH, Landry ABd, Lee YS and Katz AM: Doxorubicin-induced calcium release from cardiac sarcoplasmic reticulum vesicles. J Molec Cell Cardiol 21: 433-436, 1989.
-
(1989)
J Molec Cell Cardiol
, vol.21
, pp. 433-436
-
-
Kim, D.H.1
Landry, A.Bd.2
Lee, Y.S.3
Katz, A.M.4
-
29
-
-
0027273579
-
Anthracycline-induced tension in permeabilized cardiac fibers: Evidence for the activation of the calcium release channel of sarcoplasmic reticulum
-
Boucek RJJ, Buck SH, Scott F, Oquist NL, Fleischer S and Olson RD: Anthracycline-induced tension in permeabilized cardiac fibers: evidence for the activation of the calcium release channel of sarcoplasmic reticulum. J Molec Cell Cardiol 25: 249-259, 1993.
-
(1993)
J Molec Cell Cardiol
, vol.25
, pp. 249-259
-
-
Boucek, R.J.J.1
Buck, S.H.2
Scott, F.3
Oquist, N.L.4
Fleischer, S.5
Olson, R.D.6
-
30
-
-
0033965484
-
Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca2+-ATPase gene transcription
-
Arai M, Yoguchi A, Takizawa T et al.: Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca2+-ATPase gene transcription. Circulation Res 86: 8-14, 2000.
-
(2000)
Circulation Res
, vol.86
, pp. 8-14
-
-
Arai, M.1
Yoguchi, A.2
Takizawa, T.3
-
31
-
-
0033178477
-
Persistent effects of doxorubicin on cardiac gene expression
-
Boucek RJJ, Miracle A, Anderson M, Engelmann R, Atkinson J and Dodd D: Persistent effects of doxorubicin on cardiac gene expression. J Molec Cell Cardiol 31: 1435-1446, 1999.
-
(1999)
J Molec Cell Cardiol
, vol.31
, pp. 1435-1446
-
-
Boucek, R.J.J.1
Miracle, A.2
Anderson, M.3
Engelmann, R.4
Atkinson, J.5
Dodd, D.6
|