메뉴 건너뛰기




Volumn 95, Issue 5, 2000, Pages 1580-1587

Patients with myelodysplastic syndromes benefit from palliative therapy with amifostine, pentoxifylline, and ciprofloxacin with or without dexamethasone

Author keywords

[No Author keywords available]

Indexed keywords

AMIFOSTINE; CIPROFLOXACIN; DEXAMETHASONE; PENTOXIFYLLINE; RADIOPROTECTIVE AGENT;

EID: 0034161542     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.5.1580.005k45_1580_1587     Document Type: Article
Times cited : (73)

References (40)
  • 2
    • 0031694754 scopus 로고    scopus 로고
    • Differentiation therapy of myelodysplastic syndromes: Fact or fiction?
    • Santini V, Ferrini PR. Differentiation therapy of myelodysplastic syndromes: fact or fiction? [review]. Br J Haematol. 1998;102:1124-1138.
    • (1998) Br J Haematol. , vol.102 , pp. 1124-1138
    • Santini, V.1    Ferrini, P.R.2
  • 3
    • 0027406343 scopus 로고
    • Busulfan-based regimens and allogeneic bone marrow transplantation in patients with myelodysplastic syndromes
    • Ratanatharathom V, Karanes C, Uberti J, et al. Busulfan-based regimens and allogeneic bone marrow transplantation in patients with myelodysplastic syndromes. Blood. 1993;81:2194-2199.
    • (1993) Blood , vol.81 , pp. 2194-2199
    • Ratanatharathom, V.1    Karanes, C.2    Uberti, J.3
  • 4
    • 13344282097 scopus 로고    scopus 로고
    • Allogeneic marrow transplantation for refractory anemia: A comparison of two preparative regimens and analysis of prognostic factors
    • Anderson JE, Appelbaum FR, Schoch G, et al. Allogeneic marrow transplantation for refractory anemia: a comparison of two preparative regimens and analysis of prognostic factors. Blood. 1996;87:51-58.
    • (1996) Blood , vol.87 , pp. 51-58
    • Anderson, J.E.1    Appelbaum, F.R.2    Schoch, G.3
  • 5
    • 0023571993 scopus 로고
    • Effects of recombinant human granulocyte macrophage colony-stimulating factor in patients with myelodysplastic syndromes
    • Vadhan-Raj S, Keating M, Lemaistre A, et al. Effects of recombinant human granulocyte macrophage colony-stimulating factor in patients with myelodysplastic syndromes. N Engl J Med. 1987;317:1545-1552.
    • (1987) N Engl J Med. , vol.317 , pp. 1545-1552
    • Vadhan-Raj, S.1    Keating, M.2    Lemaistre, A.3
  • 6
    • 0025370701 scopus 로고
    • Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor
    • Negrin RS, Haiber DH, Nagler A, et al. Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor. Blood. 1990;76:36-43.
    • (1990) Blood , vol.76 , pp. 36-43
    • Negrin, R.S.1    Haiber, D.H.2    Nagler, A.3
  • 7
    • 0000399876 scopus 로고
    • Phase III randomized multicenter trial of G-CSF vs observation for myelodysplastic syndromes (MDS)
    • Greenberg P, Taylor K, Larson R, et al. Phase III randomized multicenter trial of G-CSF vs observation for myelodysplastic syndromes (MDS). Blood. 1993;82(suppl 1):196a.
    • (1993) Blood , vol.82 , Issue.SUPPL. 1
    • Greenberg, P.1    Taylor, K.2    Larson, R.3
  • 8
    • 0028953367 scopus 로고
    • Efficacy of erythropoietin in the myelodysplastic syndromes: An analysis of 205 patients in 17 studies
    • Hellstrom-Lindberg E. Efficacy of erythropoietin in the myelodysplastic syndromes: an analysis of 205 patients in 17 studies. Br J Haematol. 1995;89:67-71.
    • (1995) Br J Haematol. , vol.89 , pp. 67-71
    • Hellstrom-Lindberg, E.1
  • 9
    • 2642686614 scopus 로고    scopus 로고
    • Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor plus erythropoietin: Results from a randomized phase 11 study and long-term follow-up of 71 patients
    • Hellstrom-Lindberg E, Ahlgren T, Beguin Y, et al. Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor plus erythropoietin: results from a randomized phase 11 study and long-term follow-up of 71 patients. Blood. 1998;92:68-75.
    • (1998) Blood , vol.92 , pp. 68-75
    • Hellstrom-Lindberg, E.1    Ahlgren, T.2    Beguin, Y.3
  • 10
    • 0024553901 scopus 로고
    • Effect of recombinant human granulocyte macrophage colony-stimulating factor in patients with myelodysplastic syndromes with excess blasts
    • Hermann F, Lindemann A, Klein H, et al. Effect of recombinant human granulocyte macrophage colony-stimulating factor in patients with myelodysplastic syndromes with excess blasts. Leukemia. 1989;3:335-338.
    • (1989) Leukemia , vol.3 , pp. 335-338
    • Hermann, F.1    Lindemann, A.2    Klein, H.3
  • 11
    • 0031816074 scopus 로고    scopus 로고
    • Standard and low-dose chemotherapy for the treatment of myelodysplastic syndromes
    • Cheson BD. Standard and low-dose chemotherapy for the treatment of myelodysplastic syndromes. Leuk Res. 1998;22:17-21.
    • (1998) Leuk Res. , vol.22 , pp. 17-21
    • Cheson, B.D.1
  • 12
    • 0031870632 scopus 로고    scopus 로고
    • Intensive therapy for high-risk myelodysplastic syndromes and the biologic significance of karyotype abnormalities
    • Hiddemann W, Jahns-Streubel G, Verbeek W, Wormann B, Haase D, Schoch C. Intensive therapy for high-risk myelodysplastic syndromes and the biologic significance of karyotype abnormalities. Leuk Res. 1998;22:23-26.
    • (1998) Leuk Res. , vol.22 , pp. 23-26
    • Hiddemann, W.1    Jahns-Streubel, G.2    Verbeek, W.3    Wormann, B.4    Haase, D.5    Schoch, C.6
  • 13
    • 0025645740 scopus 로고
    • Apoptosis is a common histopathological finding in myelodysplasia: The correlate of ineffective hematopoiesis
    • Clark DM, Lampert IA. Apoptosis is a common histopathological finding in myelodysplasia: the correlate of ineffective hematopoiesis. Leuk Lymphoma. 1990;2:415-418.
    • (1990) Leuk Lymphoma , vol.2 , pp. 415-418
    • Clark, D.M.1    Lampert, I.A.2
  • 14
    • 0029020851 scopus 로고
    • Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes
    • Raza A, Gezer S, Mundle S, et al. Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes. Blood. 1995;86:268-276.
    • (1995) Blood , vol.86 , pp. 268-276
    • Raza, A.1    Gezer, S.2    Mundle, S.3
  • 16
    • 0030926080 scopus 로고    scopus 로고
    • Fas/ Apo-I (CD95) expression and apoptosis in patients with myelodysplastic syndromes
    • Bouscary D, De Vos J, Guesnu M, et al. Fas/ Apo-I (CD95) expression and apoptosis in patients with myelodysplastic syndromes. Leukemia. 1997;11:839-845.
    • (1997) Leukemia , vol.11 , pp. 839-845
    • Bouscary, D.1    De Vos, J.2    Guesnu, M.3
  • 17
    • 10144232108 scopus 로고    scopus 로고
    • Indication of an involvement of interleukin-Iβ converting enzyme (ICE)-like protease in intramedullary apoptotic cell death in the bone marrows of patients with myelodysplastic syndromes (MDS)
    • Mundle SD, Venugopal P, Pandav DV, et al. Indication of an involvement of interleukin-Iβ converting enzyme (ICE)-like protease in intramedullary apoptotic cell death in the bone marrows of patients with myelodysplastic syndromes (MDS). Blood. 1996;8:2640-2647.
    • (1996) Blood , vol.8 , pp. 2640-2647
    • Mundle, S.D.1    Venugopal, P.2    Pandav, D.V.3
  • 18
    • 0030294026 scopus 로고    scopus 로고
    • Measurement of apoptosis, proliferation and three cytokines in 46 patients with myelodysplastic syndromes
    • Shetty V, Mundle S, Alvi S, et al. Measurement of apoptosis, proliferation and three cytokines in 46 patients with myelodysplastic syndromes. Leuk Res. 1996;20:891-900.
    • (1996) Leuk Res. , vol.20 , pp. 891-900
    • Shetty, V.1    Mundle, S.2    Alvi, S.3
  • 19
    • 0031464758 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor alpha and interferon gamma by bone marrow cells from patients with myelodysplastic syndromes
    • Kitagawa M, Saito I, Kuwata T, et al. Overexpression of tumor necrosis factor alpha and interferon gamma by bone marrow cells from patients with myelodysplastic syndromes. Leukemia. 1997;11:2049-2054.
    • (1997) Leukemia , vol.11 , pp. 2049-2054
    • Kitagawa, M.1    Saito, I.2    Kuwata, T.3
  • 21
    • 0028618551 scopus 로고
    • A potential role for phosphatidic acid in mediating the inflammatory responses of TNF-α and IL-1β
    • Bursten W, Weeks R, West J, et al. A potential role for phosphatidic acid in mediating the inflammatory responses of TNF-α and IL-1β. Circ Shock. 1994;44:14-19.
    • (1994) Circ Shock , vol.44 , pp. 14-19
    • Bursten, W.1    Weeks, R.2    West, J.3
  • 22
    • 0027153107 scopus 로고
    • Pentoxifylline decreases tumor necrosis factor expression and serum triglycerides in people with AIDS
    • Dezube BJ, Pardee AB, Chapman B, et al. Pentoxifylline decreases tumor necrosis factor expression and serum triglycerides in people with AIDS. J Acquir Immune Defic Syndr. 1993;6:787-794.
    • (1993) J Acquir Immune Defic Syndr. , vol.6 , pp. 787-794
    • Dezube, B.J.1    Pardee, A.B.2    Chapman, B.3
  • 23
    • 0028228294 scopus 로고
    • Phase Ib trial of pentoxifylline and ciprofloxacin in patients treated with interleukin-2 and lymphokine activated killer cell therapy for metastatic renal carcinoma
    • Thompson JA, Bianco JA, Benyunes MC, Neubauer MA, Slattery JT, Fefer A. Phase Ib trial of pentoxifylline and ciprofloxacin in patients treated with interleukin-2 and lymphokine activated killer cell therapy for metastatic renal carcinoma. Cancer Res. 1994;54:3436-3441.
    • (1994) Cancer Res. , vol.54 , pp. 3436-3441
    • Thompson, J.A.1    Bianco, J.A.2    Benyunes, M.C.3    Neubauer, M.A.4    Slattery, J.T.5    Fefer, A.6
  • 25
    • 0028988790 scopus 로고
    • Pentoxifylline and ciprofloxacin in patients with myelodysplastic syndrome: A phase 11 trial
    • Nemunaitis J, Rosenfeld C, Getty L, et al. Pentoxifylline and ciprofloxacin in patients with myelodysplastic syndrome: a phase 11 trial. Am J Clin Oncol. 1993;18:189-194.
    • (1993) Am J Clin Oncol. , vol.18 , pp. 189-194
    • Nemunaitis, J.1    Rosenfeld, C.2    Getty, L.3
  • 26
    • 0025282043 scopus 로고
    • Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis in the signaling pathway
    • Han J, Thompson P, Beutler B. Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis in the signaling pathway. J Exp Med. 1990;172:391-394.
    • (1990) J Exp Med. , vol.172 , pp. 391-394
    • Han, J.1    Thompson, P.2    Beutler, B.3
  • 27
    • 0003007237 scopus 로고    scopus 로고
    • Pilot study of pentoxifylline and ciprofloxacin with or without dexamenthasone produces encouraging results in myelodysplastic syndromes: Acute leukemias VII
    • W. Hiddemann, T. Buchner, B. Wormann, et al, eds. New York: Springer-Verlag
    • Raza A, Venugopal P, Gezer S, et al. Pilot study of pentoxifylline and ciprofloxacin with or without dexamenthasone produces encouraging results in myelodysplastic syndromes: acute leukemias VII. In: W. Hiddemann, T. Buchner, B. Wormann, et al, eds. Experimental Approaches and Novel Therapies. New York: Springer-Verlag; 1998:42-51.
    • (1998) Experimental Approaches and Novel Therapies , pp. 42-51
    • Raza, A.1    Venugopal, P.2    Gezer, S.3
  • 28
    • 0031740061 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha levels decrease with anti-cytokine therapy in patients with myelodysplastic syndromes
    • Reza S, Shetty V, Dar S, Qawi H, Raza A. Tumor necrosis factor alpha levels decrease with anti-cytokine therapy in patients with myelodysplastic syndromes. J Interferon Cytokine Res. 1998;18:871-877.
    • (1998) J Interferon Cytokine Res. , vol.18 , pp. 871-877
    • Reza, S.1    Shetty, V.2    Dar, S.3    Qawi, H.4    Raza, A.5
  • 29
    • 0030735082 scopus 로고    scopus 로고
    • Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndromes
    • List AF, Brasfield F, Heaten R, et al. Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndromes. Blood. 1997;90:3364-3369.
    • (1997) Blood , vol.90 , pp. 3364-3369
    • List, A.F.1    Brasfield, F.2    Heaten, R.3
  • 30
    • 0027304592 scopus 로고
    • Treatment of the anemia of myelodysplastic syndromes using recombinant human granulocyte colony stimulating factor in combination with erythropoietin
    • Negrin RS, Stein R, Vardiman J, et al. Treatment of the anemia of myelodysplastic syndromes using recombinant human granulocyte colony stimulating factor in combination with erythropoietin. Blood. 1993;82:737-743.
    • (1993) Blood , vol.82 , pp. 737-743
    • Negrin, R.S.1    Stein, R.2    Vardiman, J.3
  • 31
    • 0024509491 scopus 로고
    • Clonal analysis of myelodysplastic syndromes: Evidence of multipotent stem cell origin
    • Janssen JWG, Buschle M, Layton M, et al. Clonal analysis of myelodysplastic syndromes: evidence of multipotent stem cell origin. Blood. 1989;73:248-254.
    • (1989) Blood , vol.73 , pp. 248-254
    • Janssen, J.W.G.1    Buschle, M.2    Layton, M.3
  • 32
    • 0030293115 scopus 로고    scopus 로고
    • The myelodysplastic syndromes in 1996: Complex stem cell disorders confounded by dual actions of cytokines
    • Raza A, Gregory SA, Preisler HD. The myelodysplastic syndromes in 1996: complex stem cell disorders confounded by dual actions of cytokines. Leuk Res. 1996;20:881-890.
    • (1996) Leuk Res. , vol.20 , pp. 881-890
    • Raza, A.1    Gregory, S.A.2    Preisler, H.D.3
  • 33
    • 0022655609 scopus 로고
    • WR-2721 protects against the hematologic toxicity of cyclophosphamide: A controlled phase 11 trial
    • Glover D, Glick JH, Weiler C, Hurowitz S, Kligermann MM. WR-2721 protects against the hematologic toxicity of cyclophosphamide: a controlled phase 11 trial. J Clin Oncol. 1986;4:574-578.
    • (1986) J Clin Oncol. , vol.4 , pp. 574-578
    • Glover, D.1    Glick, J.H.2    Weiler, C.3    Hurowitz, S.4    Kligermann, M.M.5
  • 34
    • 0029902007 scopus 로고    scopus 로고
    • Amifostine pre-treatment for protection against cyclophospamide-induced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer
    • Kemp G, Rose P, Lurain J, et al. Amifostine pre-treatment for protection against cyclophospamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer. J Clin Oncol. 1996;14:2101-2112.
    • (1996) J Clin Oncol. , vol.14 , pp. 2101-2112
    • Kemp, G.1    Rose, P.2    Lurain, J.3
  • 35
    • 0031705387 scopus 로고    scopus 로고
    • Amifostine stimulates formation of multipotent and erythroid bone marrow progenitors
    • List AF, Heaton R, Glinsmann-Gibson B, Capizzi RL. Amifostine stimulates formation of multipotent and erythroid bone marrow progenitors. Leukemia. 1998;12:1596-1602.
    • (1998) Leukemia , vol.12 , pp. 1596-1602
    • List, A.F.1    Heaton, R.2    Glinsmann-Gibson, B.3    Capizzi, R.L.4
  • 36
    • 12944332006 scopus 로고    scopus 로고
    • Suppression of telomerase activity and cytokine mrna levels in acute myelogenous leukemia cells in vivo in patients by amifostine and IL4
    • In press
    • Preisler HD, Li B, Yang J, et al. Suppression of telomerase activity and cytokine mRNA levels in acute myelogenous leukemia cells in vivo in patients by amifostine and IL4. Clin Cancer Res. In press.
    • Clin Cancer Res.
    • Preisler, H.D.1    Li, B.2    Yang, J.3
  • 37
    • 0031757027 scopus 로고    scopus 로고
    • Poor response rate to a continuous schedule of amifostine therapy for low/intermediate risk myelodysplastic patients
    • Bowen DT, Denzlinger C, Brugger W, et al. Poor response rate to a continuous schedule of amifostine therapy for low/intermediate risk myelodysplastic patients. Br J Haematol. 1998;103:785-787.
    • (1998) Br J Haematol. , vol.103 , pp. 785-787
    • Bowen, D.T.1    Denzlinger, C.2    Brugger, W.3
  • 38
    • 0019155473 scopus 로고
    • Mechanism of glucocorticosteroid activity in patients with the preleukemic syndrome (hemopoietic dysplasia)
    • Bagby Jr GC. Mechanism of glucocorticosteroid activity in patients with the preleukemic syndrome (hemopoietic dysplasia). Leuk Res. 1980;4:571-580.
    • (1980) Leuk Res. , vol.4 , pp. 571-580
    • Bagby G.C., Jr.1
  • 39
    • 0031735691 scopus 로고    scopus 로고
    • The initial transforming event in myelodysplastic syndromes may be viral: The case for cytomegalovirus
    • Raza A. The initial transforming event in myelodysplastic syndromes may be viral: the case for cytomegalovirus. Med Oncol. 1998;15:165-173.
    • (1998) Med Oncol. , vol.15 , pp. 165-173
    • Raza, A.1
  • 40
    • 0031782686 scopus 로고    scopus 로고
    • Hypothesis: Myelodysplastic syndromes may have a viral etiology
    • Raza A. Hypothesis: myelodysplastic syndromes may have a viral etiology. Int J Hematol. 1998;68:245-256.
    • (1998) Int J Hematol. , vol.68 , pp. 245-256
    • Raza, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.