Hypercholesterolemia is a prerequisite for puromycin inducible damage in mouse kidney

Kidney International

Volumn 63, Issue 1, 2003, Pages 107-112

  Cheng, Zhu Zhu ^a   PäTäri, Anu ^b   Aalto Setälä, Katriina ^c   Novikov, Dmitry ^d   Schlöndorff, Detlef ^e   Holthöfer, Harry ^a,f  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e Physiologisches Institut   (Germany)

^f UNIVERSITY OF MUNICH   (Germany)

Author keywords

Apolipoprotein E; Glomerular damage; Lipid peroxidation; Nephrin; Proteinuria; Puromycin

Indexed keywords

4 HYDROXYNONENAL; ALBUMIN; APOLIPOPROTEIN E; CHOLESTEROL; MALONALDEHYDE; MESSENGER RNA; NEPHRIN; PROBUCOL; PROTEIN ANTIBODY; PUROMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KNOCKOUT MOUSE; LIPID PEROXIDATION; MOUSE; NEPHELOMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; URINE LEVEL;

EID: 0037213069     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00726.x     Document Type: Article

References (44)

1. Kestilä M, Lenkkeri U, Männikkö M, et al: Positionally cloned gene for a novel glomerular protein-Nephrin-Is mutated in congenital nephrotic syndrome. Mol Cell 1:575-582, 1998
2. Holthöfer H, Ahola H, Solin ML, et al: Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney. Am J Pathol 155:1681-1687, 1999
3. Ruotsalainen V, Ljungberg P, Wartiovaara J, et al: Nephrin is specifically located at the slit diaphragm of glomerular podocytes. Proc Natl Acad Sci USA 96:7962-7967, 1999
4. Luimula P, Ahola H, Wang SX, et al: Nephrin in experimental glomerular disease. Kidney Int 58:1461-1468, 2000
5. Kawachi H, Koike H, Kurihara H, et al: Cloning of rat nephrin: Expression in developing glomeruli and in proteinuric states. Kidney Int 57:1949-1961, 2000
6. Kerjaschki D, Neale TJ: Molecular mechanisms of glomerular injury in rat experimental membranous nephropathy (Heymann nephritis). J Am Soc Nephrol 7:2518-2526, 1996
7. Neale TJ, Ojha PP, Exner M, et al: Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen. J Clin Invest 94:1577-1584, 1994
8. Gwinner W, Landmesser U, Brandes RP, et al: Reactive oxygen species and antioxidant defense in puromycin aminonucleoside glomerulopathy. J Am Soc Nephrol 8:1722-1731, 1997
9. Hirano T, Mamo JC, Nagano S, Sugisaki T: The lowering effect of probucol on plasma lipoprotein and proteinuria in puromycin aminonucleoside-induced nephrotic rats. Nephron 58:95-100, 1991
10. Chen A, Wei CH, Sheu LF, et al: Induction of proteinuria by adriamycin or bovine serum albumin in the mouse. Nephron 69: 293-300, 1995
11. Amore A, Mazzucco G, Cavallo F, et al: Adriamycin-induced proteinuria in nude mice: An immune-system-mediated toxic effect. Nephrol Dial Transplant 11:1012-1018, 1996
12. Keane WF, Kasiske BL: Hyperlipidemia in the nephrotic syndrome. N Engl J Med 323:603-604, 1990
13. Kaysen GA, Myers BD, Couser WG, et al: Mechanisms and consequences of proteinuria. Lab Invest 54:479-498, 1986
14. Plump AS, Smith JD, Hayek T, et al: Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71:343-353, 1992
15. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502, 1972
16. Holthöfer H, Kretzler M, Haltia A, et al: Altered gene expression and functions of mitochondria in human nephrotic syndrome. FASEB J 13:523-532, 1999
17. Holthöfer H, Reivinen J, Miettinen A: Nephron segment and cell-type specific expression of gangliosides in the developing and adult kidney. Kidney Int 45:123-130, 1994
18. Ahola H, Wang SX, Luimula P, et al: Cloning and expression of the rat nephrin homolog. Am J Pathol 155:907-913, 1999
19. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ: Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299, 1979
20. Delye C, Corio-Costet MF: Rapid isolation of both double-stranded RNA and PCR-suitable DNA from the obligate biotrophic phytopathogenic fungus Uncinula necator using a commercially available reagent. J Virol Methods 74:149-153, 1998
21. Vernier R, Papermaster B, Good R: Aminonucleoside nephrosis: I. Electronmicroscopic study of renal lesions in rat. J Exp Med 109: 115-126, 1959
22. Caulfield JP, Reid JJ, Farquhar MG: Alterations of the glomerular epithelium in acute aminonucleoside nephrosis. Evidence for formation of occluding junctions and epithelial cell detachment. Lab Invest 34:43-59, 1976
23. Pierce GB, Nakane PK: Basement membranes. Synthesis and deposition in response to cellular injury. Lab Invest 21:27-41, 1969
24. Kanwar YS, Manaligod JR, Krakower CA: Aminonucleoside nephrosis in PRO/Re mice. Proc Soc Exp Biol Med 155:339-345, 1977
25. Keane WF, Kasiske BL, O'Donnell MP: Lipids and progressive glomerulosclerosis. A model analogous to atherosclerosis. Am J Nephrol 8:261-271, 1988
26. Neale TJ, Ullrich R, Ojha P, et al: Reactive oxygen species and neutrophil respiratory burst cytochrome b558 are produced by kidney glomerular cells in passive Heymann nephritis. Proc Natl Acad Sci USA 90:3645-3649, 1993
27. Solin ML, Pitkänen S, Taanman JW, Holthöfer H: Mitochondrial dysfunction in congenital nephrotic syndrome. Lab Invest 80: 1227-1232, 2000
28. Diamond JR, Bonventre JV, Karnovsky MJ: A role for oxygen free radicals in aminonucleoside nephrosis. Kidney Int 29:478-483, 1986
29. Ghiggeri GM, Cercignani G, Ginevri F, et al: Puromycin amino-nucleoside metabolism by glomeruli and glomerular epithelial cells in vitro. Kidney Int 40:35-42, 1991
30. Ricardo SD, Bertram JF, Ryan GB: Reactive oxygen species in puromycin aminonucleoside nephrosis: In vitro studies. Kidney Int 45:1057-1069, 1994
31. Nosaka K, Takahashi T, Nishi T, et al: An adenosine deaminase inhibitor prevents puromycin aminonucleoside nephrotoxicity. Free Radic Biol Med 22:597-605, 1997
32. Johnson RJ, Lovett D, Lehrer RI, et al: Role of oxidants and proteases in glomerular injury. Kidney Int 45:352-359, 1994
33. Solin ML, Ahola H, Haltia A, et al: Lipid peroxidation in human proteinuric disease. Kidney Int 59:481-487, 2001
34. Nickenig G, Sachinidis A, Michaelsen F, et al: Upregulation of vascular angiotensin II receptor gene expression by low-density lipoprotein in vascular smooth muscle cells. Circulation 95:473-478, 1997
35. Nickenig G, Jung O, Strehlow K, et al: Hypercholesterolemia is associated with enhanced angiotensin AT1-receptor expression. Am J Physiol 272:H2701-H2707, 1997
36. Nickenig G, Baumer AT, Temur Y, et al: Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men. Circulation 100:2131-2134, 1999
37. Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW: Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74:1141-1148, 1994
38. Darley-Usmar VM, McAndrew J, Patel R, et al: Nitric oxide, free radicals and cell signalling in cardiovascular disease. Biochem Soc Trans 25:925-929, 1997
39. Benigni A, Tomasoni S, Gagliardini E, et al: Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis. J Am Soc Nephrol 12:941-948, 2001
40. Rantanen M, Palmén T, Poïtän A, et al: Nephrin trap mice lack slit membranes, show fibrotic glomeruli, and cystic tubular lesions. J Am Soc Nephrol 13:1586-1594, 2002
41. Putaala H, Soininen R, Kilpeläinen P, et al: The murine nephrin gene is specifically expressed in kidney, brain and pancreas: Inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet 10:1-8, 2001
42. Topham PS, Kawachi H, Haydar SA, et al: Nephritogenic mAb 5-1-6 is directed at the extracellular domain of rat nephrin. J Clin Invest 104:1559-1566, 1999
43. Luimula P, Aaltonen P, Ahola H, et al: Alternatively spliced nephrin in experimental glomerular disease of the rat. Pediatr Res 48:759-762, 2000
44. Doublier S, Ruotsalainen V, Salvidio G, et al: Nephrin redistribution on podocytes is a potential mechanism for proteinuria in patients with primary acquired nephrotic syndrome. Am J Pathol 158:1723-1731, 2001