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Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 11, 1998, Pages 1337-1342

Sulfonamide derivatives of benzylamine block cholesterol biosynthesis in HepG2 cells: A new type of potent squalene epoxidase inhibitors

(6) Gotteland, J P a Loubat, C a Planty, B a Junquero D a Delhon, A a Halazy, S a

a INSTITUT DE RECHERCHE PIERRE FABRE (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLAMINE; CHOLESTEROL; ENZYME INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MONOOXYGENASE INHIBITOR; SQUALENE MONOOXYGENASE; SQUALENE MONOOXYGENASE INHIBITOR; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; DRUG ACTIVITY; DRUG DESIGN; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BENZYLAMINES; CELL LINE; CHOLESTEROL; DOGS; ENZYME INHIBITORS; HUMANS; LIVER; OXYGENASES; RATS; SQUALENE MONOOXYGENASE; SULFONAMIDES; SWINE;

EID: 0032474517 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(98)00213-3 Document Type: Article

Times cited : (13)

References (13)

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