Hydrogen peroxide mediates higher order chromatin degradation

Neurochemistry International

Volumn 42, Issue 2, 2003, Pages 123-129

  Bai, H ^a   Konat, G W ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

C6 cells; Hypochlorite; Nitric oxide; Oxidative stress; Peroxides

Indexed keywords

DNA FRAGMENT; ENDONUCLEASE; GENOMIC DNA; HYDROGEN PEROXIDE; HYPOCHLORITE; NITRIC OXIDE DONOR; OXIDIZING AGENT; SINGLE STRANDED DNA; SPERMINE DERIVATIVE; TERT BUTYL HYDROPEROXIDE;

ANIMAL CELL; ARTICLE; CHROMATIN STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; GEL ELECTROPHORESIS; GLIOMA CELL; NONHUMAN; NUCLEIC ACID STRUCTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN NEOPLASMS; CELL NUCLEUS; CHROMATIN; DNA; GLIOMA; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; KINETICS; NERVE DEGENERATION; NITRIC OXIDE DONORS; OXIDANTS; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SPERMINE; TERT-BUTYLHYDROPEROXIDE; TUMOR CELLS, CULTURED;

EID: 0037210084     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(02)00072-4     Document Type: Article

References (30)

1. Bae Y.S., Kang S.W., Seo M.S., Baines I.C., Tekle E., Chock P.B., Rhee S.G. Epidermal growth factor (EGF)-induced generation of hydrogen peroxide: role in EGF receptor-mediated tyrosine phosphorylation. J. Biol. Chem. 272:1997;217-221.
2. Beere H.M., Chresta C.M., Alejo-Herberg A., Skladanowski A., Dive C., Larsen A.K., Hickman J.A. Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apoptosis. Mol. Pharmacol. 47:1995;986-996.
3. Bhat N.R., Zhang P. Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death. J. Neurochem. 72:1999;112-119.
4. Bode J., Kohwi Y., Dickinson L., Joh T., Klehr D., Mielke C., Kohwi-Shigematsu T. Biological significance of unwinding capability of nuclear matrix-associated DNAs. Science. 255:1992;195-197.
5. Breen A.P., Murphy J.A. Reactions of oxyl radicals with DNA. Free Rad. Biol. Med. 18:1995;1033-1077.
6. Bredesen D.E. Neural apoptosis. Ann. Neurol. 38:1995;839-851.
7. Brown D.G., Sun X.M., Cohen G.M. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268:1993;3037-3039.
8. Cohen G.M., Sun X.M., Fearnhea H., MacFarlane M., Brown D.G., Snowden R.T., Dinsdale D. Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. J. Immunol. 153:1994;507-516.
9. Dickinson L.A., Joh T., Kohwi Y., Kohwi-Shigematsu T. A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Cell. 70:1992;631-645.
10. Halliwell B., Aruoma O.I. DNA damage by oxygen-derived species: its mechanism and measurment in mammalian systems. FEBS Lett. 281:1991;9-19.
11. Henle E.S., Linn S. Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide. J. Biol. Chem. 272:1997;19095-19098.
12. 2 in vitro. Brain Res. 671:1995;181-186.
13. Konat G.W., Mouzannar R., Bai H. Higher order chromatin degradation in glial cells: the role of calcium. Neurochem. Int. 39:2001;179-186.
14. Kroemer G., Zamzami N., Susin S.A. Mitochondrial control of apoptosis. Immunol. Today. 18:1997;43-51.
15. Lagarkova M.A., Iarovaia O.V., Razin S.V. Large scale fragmentation of mammalian DNA in the course of apoptosis procedes via excision of chromosomal DNA loops and their oligomers. J. Biol. Chem. 270:1995;20239-20245.
16. Lee S.R., Kwon K.S., Kim S.R., Rhee S.G. Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273:1998;15366-15372.
17. Mouzannar R., Miric S.J., Wiggins R.C., Konat G.W. Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments. Neurochem. Int. 38:2001;9-15.
18. Oberhammer F., Wilson J.W., Dive C., Morris I.D., Hickman J.A., Wakeling A.E., Walker P.R., Sikorska M. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12:1993;3679-3684.
19. Pittman, R.N., Messam, C.A., Mills, J.C., 1999. Asynchronous death as a characteristic feature of apoptosis. In: Kaliatos, V.E., Rata, R.R. (Eds.), Cell Death and Diseases of the Nervous System. Humana Press, Totowa, 1999, pp. 29-43.
20. Quillet-Mary A., Jaffrezou J.P., Mansat V., Brodier C., Naval J., Laurent G. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J. Biol. Chem. 272:1995;21388-21395.
21. Rhee S.G. Redox signaling: hydrogen peroxide as intracellular messenger. Exp. Mol. Med. 31:1999;53-59.
22. Robinson K.A., Stewart C.A., Pye Q.N., Nguyen X., Kenney L., Salzman S., Floyd R.A., Hensley K. Redox-sensitive proteins phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte cultures. J. Neurosci. Res. 55:1999;724-732.
23. 2+-dependent cleavage of DNA into kilobase pair fragments is responsible for the initial degradation of DNA in apoptosis. J. Biol. Chem. 269:1994;14857-14860.
24. Sun X.M., Snowden R.T., Dinsdale D., Ormerod M.G., Cohen G.M. Changes in nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide. Biochem. Pharmacol. 2:1993;187-195.
25. Turker M.S., Gage B.M., Rose J.A., Elroy D., Ponomareva O.N., Stambrook P.J., Tischfield J.A. A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers. Cancer Res. 59:1999;1837-1839.
26. Um H.D., Orenstein J.M., Wahl S.M. Fas mediates apotosis in human monocytes by a reactive oxygen intermediate dependent pathway. J. Immunol. 156:1996;3469-3477.
27. Walker P.R., Sikorska M. New aspects of the mechanisms of DNA fragmentation in apoptosis. Biochem. Cell Biol. 75:1997;287-299.
28. Walker P.R., LeBlanc J., Sikorska M. Evidence that DNA fragmentation in apoptosis is initiated and propagated by single-strand breaks. Cell Death Different. 4:1997;506-515.
29. Wink D.A., Kasprzak K.S., Maragos C.M., Elespuru R.K., Misra M., Dunams T.M., Cebula T.A., Koch W.H., Andrews A.W., Allen J.S., Keefer L.K. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science. 254:1991;1001-1003.
30. 2+ in the formation of high molecular weight DNA fragments in thymocyte apoptosis. Biochem. Biophys. Res. Comm. 202:1994;120-127.