The predominant role of brain angiotensinogen and angiotensin in environmentally induced hypertension

Regulatory Peptides

Volumn 110, Issue 1, 2002, Pages 25-32

  Peng, JianFeng ^a   Kimura, Birgitta ^b   Phillips, M Ian ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Angiotensin II; Angiotensin converting enzyme; Angiotensinogen; Cold induced hypertension; mRNA

Indexed keywords

ANGIOTENSIN; ANGIOTENSINOGEN; DIPEPTIDYL CARBOXYPEPTIDASE; MESSENGER RNA; ANGIOTENSIN II;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; COLD EXPOSURE; CONTROLLED STUDY; ENVIRONMENTAL TEMPERATURE; ENZYME BLOOD LEVEL; HYPERTENSION; HYPOTHALAMUS; LIVER LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; BRAIN; COLD; DISEASE MODEL; LIVER; METABOLISM; PHYSIOLOGY; RADIOIMMUNOASSAY; SPRAGUE DAWLEY RAT; TIME;

ANGIOTENSIN II; ANGIOTENSINOGEN; ANIMALS; BLOOD PRESSURE; BRAIN; COLD; DISEASE MODELS, ANIMAL; HYPERTENSION; HYPOTHALAMUS; LIVER; MALE; PEPTIDYL-DIPEPTIDASE A; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; RENIN-ANGIOTENSIN SYSTEM; RNA, MESSENGER; TIME FACTORS;

EID: 0037207065     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(02)00156-8     Document Type: Article

References (52)

1. Therien P.M., Leblanc J., Heroux O., Dugal L.P. Effets de l'acide ascorbique sur plusieurs variabiles biologioues normalement affectees par le froid. Can. J. Res. 27:1949;349-361.
2. Peng J.-F., Phillips M.I. Opposite regulation of brain angiotensin type 1 and type 2 receptors in cold-induced hypertension. Regul. Pept. 97:2001;91-102.
3. Phillips M.I. Functions of angiotensin in the central nervous system. Annu. Rev. Physiol. 49:1987;413-435.
4. Dzau V.J., Brody T., Ellison K.E., Pratt R.E., Ingelfinger J.R. Tissue specific regulation of renin expression in the mouse. Hypertension. 9:1987;36-41.
5. Laragh J.H. Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke). J. Hum. Hypertens. 9(6):1995;385-390.
6. Field L.J., McGowan R.A., Dickinson D.P., Gross K.W. Tissue and gene specificity of mouse renin expression. Hypertension. 6:1984;597-603.
7. Jeunemaitre X., Soubrier F., Kotelevetsev Y.V., Lifton R.P., Williams C.S., Charru A.et al. Molecular basis of human hypertension: role of angiotensinogen. Cell. 71:1992;169-180.
8. Caulfield M., Lavender P., Farrall M., Munroe P., Lawson M., Turner P.et al. Linkage of the angiotensinogen gene to essential hypertension. N. Engl. J. Med. 330:1994;1629-1633.
9. Kamitani A., Rakugi H., Higaki J., Yi Z., Mikami H., Miki T.et al. Association analysis of a polymorphism of the angiotensinogen gene with essential hypertension in Japanese. J. Hum. Hypertens. 8:1994;521-524.
10. Ohkubo H., Kawakami H., Kakehi Y., Takumi T., Arai H., Yokota Y.et al. Generation of transgenic mice with elevated blood pressure by introduction of the rat renin and angiotensinogen genes. Proc. Natl. Acad. Sci. U. S. A. 87:1990;5153-5157.
11. Kimura S., Mullins J.J., Bunnemann B., Metzger R., Hilgenfeldt U., Zimmermann F.et al. High blood pressure in transgenic mice carrying the rat angiotensinogen gene. EMBO J. 11:1992;821-882.
12. Ganten D., Wagner J., Zeh K., Bader M., Michel J.B., Paul M.et al. Species specificity of renin kinetics in transgenic rats harboring the human renin and giotensinogen gene. Proc. Natl. Acad. Sci. U. S. A. 89:1992;7806-7810.
13. Fukamizu A., Sugimura K., Takimoto E., Sugiyama F., Seo M.S., Takahashi S.et al. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen gene. J. Biol. Chem. 268:1993;11617-11621.
14. Morimoto S., Cassell M.D., Beltz T.G., Johnson A.K., Davisson R.L., Sigmund C.D. Elevated blood pressure in transgenic mice with brain-specific expression of human angiotensinogen driven by the glial fibrillary acidic protein promoter. Circ. Res. 89(4):2001;365-372.
15. Davisson R.L., Ding Y., Stec D.E., Catterall J.F., Sigmund C.D. Novel mechanism of hypertension by cell-specific targeting of human angiotensinogen in transgenic mice. Physiol. Genomics. 9(1):1999;3-9.
16. Bennett C.L., Schrader A.P., Morris B.J. Cross-sectional analysis of Met235→Thr variant of angiotensinogen gene in severe, familial hypertension. Biochem. Biophys. Res. Commun. 197:1993;833-839.
17. Ward K., Hata A., Jeunemaitre X., Helin C., Nelson L., Namikawa C.et al. A molecular variant of angiotensinogen associated with preeclampsia. Genetics. 4:1993;59-61.
18. Phillips M.I. Antisense inhibition and adeno-associated viral vector delivery for reducing hypertension. Hypertension. 29:1997;77-187.
19. Phillips M.I. Gene therapy for hypertension. Hypertension. 38(2):2001;543-548.
20. Campagnole-Santos M.J., Diz D.I., Ferrario C.M. Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarii. Hypertension. II(Suppl. 1):1988;167-171.
21. Epstein A.N., Fitzsimons J.T., Rolls B.J. Drinking induced by injection of angiotensin II into the brain of the rat. J. Physiol. 210:1969;457-474.
22. 125I angiotensin II binding sites in rat brain: a quantitative autoradiographic study. Neuroscience. 18:1986;837-856.
23. Sirrett N.E., Mclean A.S., Bray J.J., Hubbard J.I. Distribution of angiotensin II receptors in rat brain. Brain Res. 122:1977;299-312.
24. Phillips M.I., Stenstrom B. Angiotensin II in rat brain comigrates with authentic angiotensin II in HPLC. Circ. Rec. 56:1985;212-219.
25. Dzau V.J. Significance of the vascular renin-angiotensin pathway. Hypertension. 8:1988;553-559.
26. Phillips M.I., Speakman E.A., Kimura B. Levels of angiotensin and molecular biology of the tissue renin-angiotensin system. Regul. Pept. 43:1992;1-20.
27. Mullins J.J., Peters J., Ganten D. Fulminant hypertension in transgenic rats harboring the mouse Ren-2 gene. Nature. 344:1990;541-544.
28. Morishita R., Gibbons G.H., Kaneda Y., Ogihara T., Dzau V.J. Novel and effective gene transfer technique for study of vascular renin-angiotensin. J. Clin. Invest. 91:1993;2580-2585.
29. Berecek K.H., Kirk K.A., Nagahama S., Oparil S. Sympathetic function in spontaneously hypertensive rats after chronic administration of captopril. Am. J. Physiol. 252:1987;H796-H806.
30. Phillips M.I., Kimura B. Brain angiotensin in the developing spontaneously hypertensive rats. J. Hypertens. 6:1988;607-612.
31. Kimura B., Mohuczy D., Tang X., Phillips M.I. Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense. Hypertension. 37(2):2001;376-380.
32. Yonge B.G., Angulo J.A., McEwen B.S., Meyers M.M. Brain and liver angiotensinogen mRNA in genetic hypertensive and normotensive rats. Hypertension. 17:1991;485-491.
33. Salaymeh B., Lee M.R., Weyhenmeyer J.A. A comparison of CNS angiotensin II binding in the hypothalamus-thalamus-septum-midbrain region of developing spontaneously hypertensive and normotensive rats. J. Hypertens. 4:1986;617-622.
34. Weyhenmeyer J., Phillips M.I. Angiotensin-like immunoreactivity in the brain of the spontaneously hypertensive rat. Hypertension. 4:1982;514-523.
35. Naruse M., Naruse K., McKenzie J.C., Schelling P., Inagami T. Regional distribution of renin and angiotensin in the brain of normotensive and spontaneously hypertensive rats. Brain Res. 333:1985;147-150.
36. Phillips M.I., Mann J.F., Haebara H., Hoffman W.E., Dietz R., Schilling P.et al. Lowering of hypertension by central saralasin in the absence of plasma renin. Nature. 270:1977;445-447.
37. 1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin. Regul. Pept. 49(2):1993;167-174.
38. Chomcynski P., Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
39. Sernia C., Shinkel T.A., Thomas W.G., Ho K.K.Y., Lincoln D. Angiotensinogen secretion by single rat pituitary cells: detection by a reverse hemolytic plaque assay and cell identification by immunocytochemistry. Neuroendocrinnology. 55:1992;308-316.
40. Holmquist B., Bunning P., Riordan J.F. A continuous spectrophotometric assay for angiotensin-converting enzyme. Anal. Biochem. 95:1979;540-545.
41. 1 receptor mRNA and angiotensinogen mRNA in brain and blood. Hypertension. 31:1998;1317-1323.
42. Weyhenmeyer J., Phillips M.I. Angiotensin-like immunoreactivity in the brain of the spontaneously hypertensive rat. Hypertension. 4:1982;514-523.
43. Hermann K., Lang R.E., Unger T., Bayer C., Ganten D. Combined high-performance liquid chromatography radioimmunoassay for the characterization and quantitative measurement of neuropeptides. J. Chromatogr. 312:1984;273.
44. Ganten D., Hermann K., Bayer C., Unger T., Lang R.E. Angiotensin synthesis in the brain and increased turnover in hypertensive rats. Science. 221:1983;869-871.
45. Healy D.P., Printz M.P. Angiotensinogen levels in the brain and cerebrospinal fluid of the genetically hypertensive rat. Hypertension. 7:1985;752-759.
46. Basso N., Ruiz P., Kurnjek M.L., Cannata M.A., Taquini A.C. The brain renin-angiotensin system and the development of DOCA-salt hypertension. Clin. Exp. Hypertens A. 7:1985;1259-1268.
47. Wielbo D., Simon A., Phillips M.I., Toffolo S. Inhibition of hypertension by peripheral administration of antisense oligodeoxynucleotides. Hypertension. 28:1996;147-151.
48. Tomita N., Morishita R., Higaki J., Aoki M., Nakamura Y., Mikami H.et al. Transient decrease in high blood pressure by in vivo transfer of antisense oligodeoxynucleotides against rat angiotensinogen. Hypertension. 26:1995;131-136.
49. Tang X., Mohuczy D., Zhang C.Y., Kimura B., Galli S.M., Phillips M.I. Intravenous angiotensinogen antisense in AAV-based vector decreases hypertension. Am. J. Physiol. 277(6 Pt. 2):1999;H2392-H2399.
50. Wielbo D., Sernia C., Gyurko R., Phillips M.I. Antisense inhibition of hypertension in the spontaneously hypertensive rats. Hypertension. 25:1995;314-329.
51. Galli S.M., Phillips M.I. Angiotensin II AT(1A) receptor antisense lowers blood pressure in acute 2 kidney-1 clip hypertension. Hypertension. 38(3):2002;674-678.
52. Kagiyama S., Varela A., Phillips M.I., Galli S.M. Antisense inhibition of brain renin-angiotensin system decreased blood pressure in chronic 2-kidney,1-clip hypertensive rats. Hypertension. 37(2):2001;371-375.