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Volumn 37, Issue 8, 2002, Pages 619-634
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Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor
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Author keywords
Androgen receptor agonists; Bicalutamide derivatives; Nonsteroidal ligands
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Indexed keywords
AMIDE;
ANDROGEN RECEPTOR;
BICALUTAMIDE DERIVATIVE;
FUNCTIONAL GROUP;
HYDROXYFLUTAMIDE;
METHYL GROUP;
MIBOLERONE;
N [4 CYANO 2 (TRIFLUOROMETHYL)PHENYL] 3 [[4 (ACETYLAMINO)PHENYL]SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 CYANO 3 (TRIFLUOROMETHYL)PHENYL] 3 [(4 AMINOPHENYL)SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 CYANO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 (ACETYLAMINO)PHENYL]SULFONYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 CYANO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 (PROPIONYLAMINO)PHENYL]SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 CYANO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 [(2 CHLOROACETYL)AMINO]PHENYL]SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 CYANO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 [(2 CHLOROACETYL)AMINO]PHENYL]SULFONYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 NITRO 2 (TRIFLUOROMETHYL)PHENYL] 3 [[4 (ACETYLAMINO)PHENYL]SULFONYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 2 HYDROXY 2 METHYL 3 [[4 [(2,2,2 TRIFLUOROACETYL)AMINO]PHENYL]SULFANYL]PROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 2 HYDROXY 2 METHYL 3 [[4 [(2,2,2 TRIFLUOROACETYL)AMINO]PHENYL]SULFONYL]PROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 2 HYDROXY 2 METHYL 3 [[4 [(METHYLSULFONYL)AMINO]PHENYL]SULFANYL]PROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 2 HYDROXY 2 METHYL 3 [[4 [(METHYLSULFONYL)AMINO]PHENYL]SULFONYL]PROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 3 [(4 AMINOPHENYL)SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 (ACETYLAMINO)PHENYL]SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 [(2 CHLOROACETYL)AMINO]PHENYL]SULFANYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
N [4 NITRO 3 (TRIFLUOROMETHYL)PHENYL] 3 [[4 [(2 CHLOROACETYL)AMINO]PHENYL]SULFONYL] 2 HYDROXY 2 METHYLPROPANAMIDE;
TRITIUM;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL CELL CULTURE;
ANIMAL TISSUE;
ARTICLE;
BINDING COMPETITION;
CONTROLLED STUDY;
DRUG POTENCY;
DRUG RECEPTOR BINDING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
GENETIC TRANSFECTION;
HUMAN;
ISOMERISM;
ISOTOPE LABELING;
LIGAND BINDING;
MALE;
NONHUMAN;
RADIOASSAY;
RAT;
RECEPTOR AFFINITY;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
TRANSCRIPTION INITIATION;
ANILIDES;
ANIMALS;
CELL LINE;
CERCOPITHECUS AETHIOPS;
DRUG DESIGN;
HUMANS;
HYDROCARBONS, AROMATIC;
LIGANDS;
RADIOLIGAND ASSAY;
RECEPTORS, ANDROGEN;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRANSCRIPTION, GENETIC;
TRANSFECTION;
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EID: 0037205938
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(02)01335-1 Document Type: Article |
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Times cited : (59)
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References (23)
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