Homer-1 mRNA in the rat suprachiasmatic nucleus is regulated differentially by the retinohypothalamic tract transmitters pituitary adenylate cyclase activating polypeptide and glutamate at time points where light phase-shifts the endogenous rhythm

Molecular Brain Research

Volumn 105, Issue 1-2, 2002, Pages 79-85

  Nielsen, Henriette S ^a   Georg, Birgitte ^a   Hannibal, Jens ^a   Fahrenkrug, Jan ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Brain slice; Circadian rhythm; Glutamate; Immediate early gene; PACAP; Suprachiasmatic nucleus

Indexed keywords

GLUTAMIC ACID; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MESSENGER RNA; NEUROTRANSMITTER; PROTEIN; PROTEIN HOMER 1; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL LEVEL; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENE EXPRESSION; IN SITU HYBRIDIZATION; IN VIVO STUDY; LIGHT DARK CYCLE; MALE; MOLECULAR WEIGHT; NERVE TRACT; NIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTOSTIMULATION; PRIORITY JOURNAL; QUANTITATIVE HISTOCHEMISTRY; RAT; SIGNAL TRANSDUCTION; SUPRACHIASMATIC NUCLEUS;

ANIMALS; CARRIER PROTEINS; CIRCADIAN RHYTHM; DARKNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; GLUTAMIC ACID; LIGHT; MALE; NEUROPEPTIDES; PHOTIC STIMULATION; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, WISTAR; RETINA; RNA, MESSENGER; SUPRACHIASMATIC NUCLEUS; UP-REGULATION; VISUAL PATHWAYS;

EID: 0037200813     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00395-9     Document Type: Article

References (27)

1. Ango F., Prézeau L., Muller T., Tu J.C., Xiao B., Worley P.F., Pin J.P., Bockaert J., Fagni L. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Nature. 411:2001;962-965.
2. Berson D.M., Dunn F.A., Takao M. Phototransduction by retinal ganglion cells that set the circadian clock. Science. 295:2002;1070-1073.
3. Brakeman P.R., Lanahan A.A., O'Brian R., Roche K., Barnes C.A., Huganir R.L., Worley P.F. Homer: a protein that selectively binds metabotropic glutamate receptors. Nature. 386:1997;284-288.
4. Chen D., Buchanan G.F., Ding J.M., Hannibal J., Gillette M.U. PACAP: a pivotal modulator of glutamatergic regulation of the suprachiasmatic circadian clock. Proc. Natl. Acad. Sci. USA. 96:1999;13468-13473.
5. Daan S., Pittendrigh C.S. A functional analysis of circadian pacemakers in nocturnal rodents. II. The variability of phase response curves. J. Comp. Physiol. 106:1976;253-266.
6. Ding J.M., Buchanan G.F., Tischkau S.A., Chen D., Kuriashkina L., Faiman L.E., Alster J.M., McPherson P.S., Campbell K.P., Gillette M.U. A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. Nature. 394:1998;381-384.
7. Ding J.M., Chen D., Weber E.T., Faiman L.E., Rea M.A., Gillette M.U. Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO. Science. 266:1994;1713-1717.
8. Hannibal J., Hindersson P., Knudsen S.M., Georg B., Fahrenkrug J. The photopigment melanopsin is exclusively present in pituitary adenylate cyclase activating peptide containing retinal ganglion cells of the retinohypothalamic tract. J. Neurosci. 22:2002;1-7.
9. Hannibal J., Møller M., Ottersen O.P., Fahrenkrug J. PACAP and glutamate are co-stored in the retinohypothalamic tract. J. Comp. Neurol. 418:2000;147-155.
10. Harrington M.E., Hoque S., Hall A., Golombek D., Biello S. Pituitary adenylate cyclase activating peptide phase shifts circadian rhythms in a manner similar to light. J. Neurosci. 19:1999;6637-6642.
11. Kato A., Ozawa F., Saitoh Y., Hirai K., Inokuchi K. vesl, a gene encoding VASP/Ena family-related protein, is upregulated during seizure, long-term potentiation, and synaptogenesis. FEBS Lett. 412:1997;183-189.
12. Kopp M.D.A., Meissl H., Dehghani F., Korff H.-W. The pituitary adenylate cyclase-activating polypeptide modulates glutamatergic calcium signalling: investigations on rat suprachiasmatic nucleus neurons. J. Neurochem. 79:2001;161-171.
13. Kornhauser J.M., Mayo K.E., Takahashi J.S. Light, immediate-early genes, and circadian rhythms. Behav. Genet. 26:1996;221-240.
14. Mintz E.M., Marvel C.L., Gillespie C.F., Price K.M., Albers H.E. Activation of NMDA receptors in the suprachiasmatic nucleus produces light-like phase shifts of the circadian clock in vivo. J. Neurosci. 15:1999;5124-5130.
15. Moore R.Y., Speh J.C., Card J.P. The retinohypothalamic tract originates from a distinct subset of retinal ganglion cells. J. Comp. Neurol. 352:1995;351-366.
16. Naisbitt S., Kim E., Tu J.C., Xiao B., Sala C., Valtschanoff J., Weinberg R.J., Worley P.F., Sheng M. Shank, a novel family of postsynaptic density proteins that binds to NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron. 23:1999;569-582.
17. Nielsen H.S., Hannibal J., Knudsen S.M., Fahrenkrug J. Pituitary adenylate cyclase-activating polypeptide induces period1 and period2 gene expression in the rat suprachiasmatic nucleus during late night. Neuroscience. 103:2001;433-441.
18. Obrietan K., Impey S., Storm D.R. Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei. Nat. Neurosci. 1:1998;693-700.
19. Park H.T., Kang E.K., Bae K.W. Light regulates Homer mRNA expression in the rat suprachiasmatic nucleus. Mol. Brain Res. 52:1997;318-322.
20. Piggins H.D., Marchant E.G., Goguen D., Rusak B. Phase-shifting effects of pituitary adenylate cyclase activating polypeptide on hamster wheel-running rhythms. Neurosci. Lett. 305:2001;25-28.
21. Prosser R.A., McArthur A.J., Gillette M.U. cGMP induces phase shifts of a mammalian circadian pacemaker at night, in antiphase to cAMP effects. Proc. Natl. Acad. Sci. USA. 86:1989;6812-6815.
22. Sato M., Suzuki K., Nakanishi S. NMDA receptor stimulation and brain-derived neurotrophic factor upregulate Homer 1a mRNA via the mitogen-activated protein kinase cascade in cultured cerebellar granule cells. J. Neurosci. 21:2001;3797-3805.
23. Summer T.L., Ferraro J.S., McCormack C.E. Phase-response and Aschoff illuminance curves for locomotor activity rhythm of the rat. Am. J. Physiol. 246:1984;R299-R304.
24. Tu J.C., Xiao B., Naisbitt S., Yuan J.P., Petralia R.S., Brakeman P., Doan A., Aakalu V.K., Lanahan A.A., Sheng M., Worley P.F. Coupling of mGluR/Homer and the PSD-95 complexes by the shank family of postsynaptic density proteins. Neuron. 23:1999;583-592.
25. 3 receptors. Neuron. 21:1998;717-726.
26. Xiao B., Tu J.C., Worley P.F. Homer: a link between neural activity and glutamate receptor function. Curr. Opin. Neurobiol. 10:2000;370-374.
27. Yan L., Takekida S., Shigeyoshi Y., Okamura H. Per1 and Per2 gene expression in the rat suprachiasmatic nucleus: circadian profile and the compartment-specific response to light. Neuroscience. 94:1999;141-150.