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Journal of Biological Chemistry

Volumn 277, Issue 35, 2002, Pages 32149-32156

The structural bases of antibiotic resistance in the clinically derived mutant β-lactamases TEM-30, TEM-32, and TEM-34

(3) Wang, Xiaojun a Minasov, George a Shoichet, Brian K a

a NORTHWESTERN UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; CROSSLINKING; ELECTRONS; ENZYME KINETICS; ENZYMES; HYDROGEN BONDS; X RAY CRYSTALLOGRAPHY;

NUCLEOPHILICITY;

ANTIBIOTICS;

ARGININE; BETA LACTAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; CARBOXYLIC ACID; CLAVULANIC ACID; ISOLEUCINE; METHIONINE; MUTANT PROTEIN; PENICILLIN G; PROTEIN; PROTEIN TEM 30; PROTEIN TEM 32; PROTEIN TEM 34; SERINE; SULBACTAM; TAZOBACTAM; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CONFORMATIONAL TRANSITION; CROSS LINKING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME STABILITY; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CRYSTALLOGRAPHY, X-RAY; KINETICS; MODELS, MOLECULAR; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN DENATURATION; RECOMBINANT PROTEINS; THERMODYNAMICS;

EID: 0037200056 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M204212200 Document Type: Article

Times cited : (68)

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