Spinal norepinephrine release from nitric oxide species is not increased following peripheral nerve injury in rats

Brain Research

Volumn 947, Issue 2, 2002, Pages 199-203

  Zhu, Xiaoying ^a   Li, Xinhui ^a   Eisenach, James C ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Neuropathic pain; Nitric oxide; Norepinephrine; Spinal cord

Indexed keywords

6 NITRIC OXIDE NOREPINEPHRINE; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; NITRIC OXIDE; NORADRENALIN; S NITROSOCYSTEINE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INCUBATION TIME; LUMBAR SPINAL CORD; MALE; NERVE LIGATION; NONHUMAN; NORADRENALIN RELEASE; NORADRENERGIC SYSTEM; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; MALE; NITRIC OXIDE; NITRIC OXIDE DONORS; NOREPINEPHRINE; PERIPHERAL NERVES; RATS; RATS, SPRAGUE-DAWLEY; S-NITROSOTHIOLS; SPINAL CORD; SYNAPTOSOMES;

EID: 0037199782     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)02924-4     Document Type: Article

References (21)

1. Intravenous opioids stimulate norepinephrine and acetylcholine release in spinal cord dorsal horn. Systematic studies in sheep and an observation in a human
2. Intrathecal S-nitroso-N-acetylpenicillamine and L-cysteine attenuate nerve injury-induced allodynia through noradrenergic activation in rats
3. Formation of 6-nitro-norepinephrine from nitric oxide and norepinephrine in the spinal cord and its role in spinal analgesia
4. Transmitters involved in antinociception in the spinal cord
5. Painful neuropathy: Altered central processing maintained dynamically by peripheral input
6. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
7. Intrathecal alpha 2-adrenergic agonists stimulate acetylcholine and norepinephrine release from the spinal cord dorsal horn in sheep. An in vivo microdialysis study
8. Pharmacologic and therapeutic significance of alpha-adrenoceptor subtypes
9. S-nitroso-l-cysteine releases norepinephrine in rat spinal synaptosomes
10. 6-NO(2)-norepinephrine increases norepinephrine release and inhibits norepinephrine uptake in rat spinal synaptosomes
11. Characterization of nitric oxide generator-induced hippocampal [3H]norepinephrine release. I. The role of glutamate
12. Characterization of nitric oxide generator-induced hippocampal [3H]norepinephrine release. II. The role of calcium, reverse norepinephrine transport and cyclic 3′,5′-guanosine monophosphate
13. Chronic neuropathic pain and its control by drugs
14. Role of spinal NO in antiallodynic effect of intrathecal clonidine in neuropathic rats
15. Involvement of L-type-like amino acid transporters in S-nitrosocysteine-stimulated noradrenaline release in the rat hippocampus
16. Bioactive 6-nitronorepinephrine identified in mammalian brain
17. Spinal nitric oxide mediates antinociception from intravenous morphine
18. Alpha 2A subtype of presynaptic alpha 2-adrenoceptors modulates the release of [3H]-noradrenaline from rat spinal cord
19. Intravenous morphine increases release of nitric oxide from spinal cord by an alpha-adrenergic and cholinergic mechanism
20. Location and characteristics of nitric oxide synthase in sheep spinal cord and its interaction with alpha(2)-adrenergic and cholinergic antinociception
21. Nitration of catecholamines with nitrogen oxides in mild conditions: A hypothesis for the reactivity of NO in physiologic systems