Route-of-entry and brain tissue partition coefficients for common superfund contaminants

Journal of Toxicology and Environmental Health - Part A

Volumn 65, Issue 24, 2002, Pages 2075-2086

  Thrall, Karla D ^a   Gies, Richard A ^a   Muniz, Juan ^b   Woodstock, Angela D ^a   Higgins, Greg ^b  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; ENVIRONMENTAL CHEMICAL; ORTHO XYLENE; TOLUENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN TISSUE; CONTROLLED STUDY; IN VITRO STUDY; LITERATURE; LUNG; MALE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; SKIN; STOMACH; TECHNIQUE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, GAS; ENVIRONMENTAL POLLUTANTS; HAZARDOUS WASTE; HUMANS; HYDROCARBONS, CHLORINATED; MALE; MODELS, BIOLOGICAL; ORGANIC CHEMICALS; RATS; RATS, INBRED F344; SOLVENTS; UNITED STATES;

ANIMALIA;

EID: 0037184669     PISSN: 15287394     EISSN: None     Source Type: Journal    
DOI: 10.1080/00984100290071838     Document Type: Article

References (23)

1. Andersen, M. E., Krewski, D., and Withey, J. R. 1993. Physiological pharmacokinetics and cancer risk assessment. Cancer Lett. 69:1-14.
2. Béliveau, M., and Krishnan, K. 2000a. Estimation of rat blood:Air partition coefficients of volatile organic chemicals using reconstituted mixtures of blood components. Toxicol. Lett. 116:183-188.
3. Béliveau, M., and Krishnan, K. 2000b. Concentration dependency of rat blood:Air partition coefficients of some volatile organic chemicals. J. Toxicol. Environ. Health A 60:377-389.
4. Corley, R. A., Gordon, S. M., and Wallace, L. A. 2000. Physiologically based pharmacokinetic modeling of the temperature-dependent dermal absorption of chloroform by humans following bath water exposures. Toxicol. Sci. 53:13-23.
5. Dallas, C. E., Chen, X. M., Muralidhara, S. Varkonyi, P., Tackett, R. L., and Bruckner, J. V. 1994. Development of a physiologically based pharmacokinetic model for perchloroethylene using tissue concentration-time data. Toxicol. Appl. Pharmacol. 128:50-59.
6. Dallas, C. E., Chen, X. M., Muralidhara, S. Varkonyi, P., Tackett, R. L., and Bruckner, J. V. 1995. Physiologically based pharmacokinetic model useful in prediction of the influence of species, dose, and exposure route on perchloroethylene pharmacokinetics. J. Toxicol. Environ. Health 44:301-317.
7. Fiserova-Bergerova, V., and Diaz, M. L. 1986. Determination and prediction of tissue-gas partition coefficients. Int. Arch. Occup. Environ. Health 58:75-87.
8. Fiserova-Bergerova, V., Tichy, M., and DiCarlo, F. J. 1984. Effects of biosolubility on pulmonary uptake and disposition of gases and vapors for lipophilic chemicals. Drug Metab. Rev. 15:1033-1070.
9. Fisher, J. W., Whittaker, T. A., Taylor, D. H., Clewell, H. J. III, and Andersen, M. E. 1989. Physiologically based pharmacokinetic modeling of the pregnant rat: A multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid. Toxicol. Appl. Pharmacol. 99:395-414.
10. Gallo, J. M., Lam, F. C., and Perrier, D. G. 1987. Pharmacometrics: Area method for the estimation of partition coefficients for physiological pharmacokinetic models. J. Pharmacokin. Biopharm. 15:271-280.
11. Gargas, M. L., Burgess, R. J., Voisard, D. E., Cason, G. H., and Andersen, M. E. 1989. Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 98:87-99.
12. Haddad, S., Charest-Tardif, G., and Krishnan, K. 2000. Physiologically based modeling of the maximal effect of metabolic interactions on the kinetics of components of complex chemical mixtures. J. Toxicol. Environ. Health A 61:209-223.
13. Jepson, G. W., Hoover, D. K., Black, R. K., McCafferty, J. D., Mahle, D. A., and Gearhart, J. M. 1994. A partition coefficient determination method for nonvolatile chemicals in biological tissues. Fundam. Appl. Toxicol. 22:519-524.
14. Johnson, B. L., and DeRosa, C. T. 1997. The toxicologic hazard of Superfund hazardous waste sites. Rev. Environ. Health 12:235-251.
15. Kohr, S. P., and Mayersohn, M. 1991. Potential error in the measurement of tissue to blood distribution coefficients in physiological pharmacokinetic modeling: Residual tissue blood. I. Theoretical considerations. Drug Metab. Dispos. 19:478-485.
16. Krishnan, K., and Brodeur, J. 1991. Toxicological consequences of combined exposure to environmental pollutants. Arch. Complex Environ. Stud. 3:1-106.
17. Lin, J. H., Sugiyama, Y., Awazu, S., and Hanano, M. 1982. In vitro and in vivo evaluation of the tissue to blood partition coefficients for physiological pharmacokinetic models. J. Pharmacokinet. Biopharm. 10:637-647.
18. Mattie, D. R., Bates, G. D., Jepson, G. W., Fisher, J. W., and McDougal, J. N. 1994. Determination of skin:Air partition coefficients for volatile chemicals: Experimentai method and applications. Fundam. Appl. Toxicol. 22:51-57.
19. Sato, A., and Nakajima, T. 1979. Partition coefficients of some aromatic hydrocarbons and ketones in water, blood and oil. Br. J. Ind. Med. 36:231-234.
20. Suk, W. A. 1995. The NIEHS Superfund Basic Research Program: Overview and areas of future research direction. Environ. Health Perspect. 103(suppl. 1):3-5.
21. Ward, R. C., Travis, C. C., Hetrick, D. M., Andersen, M. E., and Gargas, M. L. 1988. Pharmacokinetics of tetrachloroethylene. Toxicol. Appl. Pharmacol. 83:108-117.
22. You, L., and Dallas, C. E. 1998. Regional brain dosimetry of trichloroethane in mice and rats following inhalation exposures. J. Toxicol. Environ. Health 54:285-299.
23. Young, J. F., Branham, W. S., Sheehan, D. M., Baker, M. E., Wosilait, W. D., and Luecke, R. H. 1997. Physiological "constants" for PBPK models for pregnancy. J. Toxicol. Environ. Health 52:385-401.