Regional brain dosimetry of trichloroethane in mice and rats following inhalation exposures

Journal of Toxicology and Environmental Health - Part A

Volumn 54, Issue 4, 1998, Pages 285-299

  You, Li ^a   Dallas, Cham E ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1,1 TRICHLOROETHANE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; GAS CHROMATOGRAPHY; HIPPOCAMPUS; INHALATION; MALE; MEDULLA OBLONGATA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, INHALATION; ANIMALS; AREA UNDER CURVE; CEREBRAL CORTEX; CHROMATOGRAPHY, GAS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; LIPID METABOLISM; MALE; MEDULLA OBLONGATA; MICE; RATS; RATS, SPRAGUE-DAWLEY; SOLVENTS; TRICHLOROETHANES;

ANIMALIA;

EID: 0031688061     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/009841098158854     Document Type: Article

References (32)

1. Ameno, K., Kiriu, T., Fuke C., Ameno, S., Shinohara, T., and Ijiri, I. 1992. Regional brain distribution of toluene i n rats and in a human autopsy. Arch. Toxicol. 66:153-156.
2. Arlien-Soborg, P. 1992a. 1,1,1-Trichloroethane. In Solvent neurotoxicity, pp. 291-306. Boca Raton, FL: CRC Press.
3. Arlien-Soborg, P. 1992b. Toluene. In Solvent neurotoxicity, pp. 61-106.
4. Boca Raton, FL: CRC Press. Chen, X. M., Dallas, C. E., Muralidhara, S., Srivatsan, V., and Bruckner, J. V. 1993. Analyses of volatile C2 haloethanes and haloethenes in tissues: Sample preparation and extraction. J. Chromatogr. 612:199-208.
5. Dallas, C. E., Ramanathan, R., Muralidhara, S., Gallo, J. M., and Bruckner, J. V. 1989. The uptake and elimination of 1,1,1-trichloroethane during and following inhalation exposures in rats. Toxicol. Appl. Pharmacol. 98:385-397.
6. Dallas, C. E., Chen, X. M., O'Barr, K., Muralidhara, S., Varkonyi, P., and Bruckner, J. V. 1994. Development of physiologically based pharmacokinetic model for perchloroethylene using tissue concentration-time data. Toxicol. Appl. Pharmacol. 128:50-59.
7. Dobson, S., and Jensen, A. A. 1992. 1,1,1-Trichloroethane. Environmental Health Criteria 136, Geneva: World Health Organization.
8. Evans, E. B., and Balster, R. L. 1993. Inhaled 1,1,1 -trichloroethane-produced physical dependence i n mice: Effects of drugs and vapors on withdrawal. J. Pharmacol. Exp. Ther. 264:726-733.
9. Gehring, P. J. 1968. Hepatoxic potency of various chlorinated hydrocarbon vapors relative to their narcotic and l ethal potencies in mice. Toxicol. Appl. Pharmacol. 13:287-293.
10. Gjedde, A., de la Monte, S. M., and Caronna, J. J. 1977. Cerebral blood flow and oxygen consumption in rat, measured with microspheres or xenon. Acta Physiol. Scand. 100:273-281.
11. 3H)dopa in various regions of the brain. J. Neurochem. 13:655-669.
12. Gospe, S. M., and Calaban, M. J. 1988. Central nervous system distribution of inhaled toluene. Fundam. Appl. Toxicol. 11:540-545.
13. Herd, H. D., Lipsky, M., and Martin, H. F. 1974. Cardiovascular effects of 1,1,1-trichloroethane. Arch. Environ. Health. 28:227-233.
14. Ikeda, M. 1992. Public health problems of organic solvents. Toxicol. Lett. 64/65:191-201.
15. Klaassen, C. D., and Plaa, G. L. 1966. Relative effects of various chlorinated hydrocarbons on liver and kidney function in mice. Toxicol. Appl. Pharmacol. 9:139-151.
16. Klaassen, C. D., and Plaa, G. L. 1967. Relative effects of various chlorinated hydrocarbons on liver and kidney function in dogs. Toxicol. Appl. Pharmacol. 10:119-131.
17. Kyrklund, T., and Haglid, K. G. 1991. Exposure of rats to high concentrations of 1,1,1 -trichloroethane and its effects on brain lipid and fatty acid composition. Pharmacol. Toxicol. 68:384-386.
18. Nilsson, K. B. 1986. Effects of 1,1,1-trichloroethane on the cGMP metabolism in mouse brain. Acta Pharmacol. Toxicol. 58:318-326.
19. Nilsson, K. B. 1987. Effects of 1,1,1-trichloroethane on synaptosomal calcium accumulation in mouse brain. Pharmacol. Toxicol. 61:215-219.
20. Plaa, G. L., and Larson, R. E. 1965. Relative nephrotoxic properties of chlorinated methane, ethane, and ethylene derivatives i n mice. Toxicol. Appl. Pharmacol. 7:37-44.
21. Pyykko, K., Tahti, H., and Vapaatalo, H. 1977. Toluene concentrations in various tissues of rats after inhalation and oral administration. Arch. Toxicol. 38:169-176.
22. Raucy, J. L., Kraner, J. C., and Lasker, J. M. 1993. Bioactivation of halogenated hydrocarbons by cytochrome P4502E1. CRC Crit. Rev. Toxicol. 23:1-20.
23. Reinhardt, C. F., Mullin, L. S., and Maxfiled, M. E. 1973. Epinephrine-induced cardiac arrhythmic potential of some common industrial solvents. J. Occup. Med. 15:953-955.
24. Reitz, R. H., McDougal, J. N., Himmelstein, M. W., Nolan, R. J., and Schumann, A. M. 1988. Physiologically based pharmacokinetic modeling with methylchloroform: Implications for interspecies, high dose/low dose, and dose route extrapolations. Toxicol. Appl. Pharmacol. 95:185-199.
25. Romanelli, A., Falzoi, M., Mutti, A., Bergamaschi, E., and Franchini, I. 1986. Effects of some monocyclic aromatic solvents and their metabolites on brain dopamine in rabbits. J. Appl. Toxicol. 6: 431-435.
26. 14C]antipyrine. Am. J. Physiol. 234:H59-H66.
27. 14C]Methyl chloroform (1,1,1 -trichloroethane): Pharmacokinetics in rats and mice following inhalation exposure. Toxicol. Appl. Pharmacol. 62:390-401.
28. Schumann, A. M., Fox, T. R., and Watanabe, P. G. 1982b. A comparison of the fate of inhaled methylchloroform (1,1,1 -trichloroethane) following single or repeated exposure in rats and mice. Fundam. Appl. Toxicol. 2:27-32.
29. Sunahara, G. I., Kalant, H., Schofield, M., and Grupp, L. 1978. Regional distribution of ethanol in the rat brain. Can. J. Physiol. Pharmacol. 56:988-992.
30. Warren, D. A., Dallas, C. E., Reigle, T. G., and Christmus, W. H. 1993. Behavioral changes during 1,1,1-trichloroethane (TRI) inhalation in rats: Relationship to brain and blood levels. Toxicologist 13:248.
31. You, L., Muralidhara, S., and Dallas, C. E. 1994a. Comparisons between operant response and 1,1,1-trichloroethane toxicokinetics in mouse blood and brain. Toxicology 93:151-163.
32. You, L., Dallas, C. E., and Muralidhara, S. 1994b. The pharmacokinetics of inhaled 1,1,1-trichloroethane following high milk intake in mice. Drug Chem. Toxicol. 17:479-498.