Human thrombocytes are able to induce a myocardial dysfunction in the ischemic and reperfused guinea pig heart mediated by free radicals-role of the GPIIb/IIIa-blocker tirofiban

Life Sciences

Volumn 71, Issue 19, 2002, Pages 2319-2329

  Seligmann, Christian ^a,b   Simsek, Yusuf ^a   Schimmer, Mike ^a   Leitsch, Tobias ^a   Bock, Andreas ^a   Schultheiss, Heinz Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

GPIIb IIIa; Guinea pig heart; Human platelets; Ischemia; Reperfusion

Indexed keywords

SCAVENGER; SUPEROXIDE DISMUTASE; THROMBIN; TIROFIBAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DRUG EFFECT; GUINEA PIG; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART WORK; MALE; NONHUMAN; THROMBOCYTE; THROMBOCYTE ADHESION;

ANIMALS; BLOOD PLATELETS; CARDIAC OUTPUT; DISEASE MODELS, ANIMAL; FIBRINOLYTIC AGENTS; GUINEA PIGS; HUMANS; MALE; MYOCARDIAL REPERFUSION INJURY; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PLATELET TRANSFUSION; SUPEROXIDE DISMUTASE; TYROSINE;

CAVIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0037183739     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)02021-0     Document Type: Article

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