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Volumn 513, Issue 2-3, 2002, Pages 235-241

Molecular basis for exaggerated sensitivity to mexiletine in the cardiac isoform of the fast Na channel

(7) Kawagoe, Hiroyuki a Yamaoka, Kaoru a Kinoshita, Eiji a Fujimoto, Yoshinori a Maejima, Hiroshi a Yuki, Tsunetsugu a Seyama, Issei a

a HIROSHIMA UNIV SCHOOL OF MEDICINE (Japan)

Author keywords

Block; HEK 293; Mexiletine; Na channel; Whole cell patch clamp

Indexed keywords

ANESTHETIC AGENT; LIDOCAINE; MEXILETINE; SODIUM CHANNEL;

ARTICLE; BINDING SITE; CELL LINE; CELL STRAIN; CONTROLLED STUDY; DEPOLARIZATION; DIAGNOSTIC TEST; DRUG SENSITIVITY; GENE MUTATION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; STIMULUS RESPONSE;

ANTI-ARRHYTHMIA AGENTS; CELLS, CULTURED; DRUG INTERACTIONS; ELECTROPHYSIOLOGY; HUMANS; MEXILETINE; MYOCARDIUM; PROTEIN ISOFORMS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 0037181127 PISSN: 00145793 EISSN: None Source Type: Journal
DOI: 10.1016/S0014-5793(02)02320-7 Document Type: Article

Times cited : (8)

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