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Volumn 43, Issue 35, 2002, Pages 6121-6125

Reaction of aziridinium ions with organometallic reagents: Optimization of the key step of ecopipam synthesis

(7) Andrews, David R a Dahanukar, Vilas H a Eckert, Jeffrey M a Gala, Dinesh a Lucas, Brian S a Schumacher, Doris P a Zavialov, Ilia A a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

Aziridines; Aziridinium ions; Electron affinity; Grignard reagents; SET mechanism

Indexed keywords

AZIRIDINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; ECOPIPAM; ORGANOMETALLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; DIASTEREOISOMER; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRECIPITATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; TEMPERATURE;

EID: 0037179217 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4039(02)01337-0 Document Type: Article

Times cited : (22)

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