Inhibition of human immunodeficiency virus type 1 replication by P-stereodefined oligo(nucleoside phosphorothioate)s in a long-term infection model

FEBS Letters

Volumn 528, Issue 1-3, 2002, Pages 48-52

  Inagawa, Takubumi ^a   Nakashima, Hideki ^b   Karwowski, Boleslaw ^c   Guga, Piotr ^c   Stec, Wojciech J ^c   Takeuchi, Hiroaki ^a   Takaku, Hiroshi ^a  

^a CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

Anti HIV 1 activity; Antisense therapy; Diastereomerically pure S ODN; gag, rev and tat genes; Long term assay; Nuclease resistance; Oligo(nucleoside phosphorothioate)s (S ODNs)

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; GAG PROTEIN; MESSENGER RNA; OLIGORIBONUCLEOTIDE; PHOSPHOROTHIOIC ACID DERIVATIVE; PHOSPHORUS;

ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; ATOM; CELL CULTURE; CHIRALITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTEREOISOMER; DRUG EFFECT; DRUG EFFICACY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; START CODON; VIRUS LOAD; VIRUS REPLICATION;

ANTI-HIV AGENTS; BASE SEQUENCE; CELL LINE; GENES, GAG; GENES, REV; GENES, TAT; HIV INFECTIONS; HIV-1; HUMANS; MODELS, BIOLOGICAL; OLIGODEOXYRIBONUCLEOTIDES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; STEREOISOMERISM; THIONUCLEOTIDES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037174125     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(02)03235-0     Document Type: Article

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