|
|
Volumn 12, Issue 6, 2002, Pages 865-868
|
|
Imidazo[5,1-f][1,2,4]triazin-4(3H)-ones, a new class of potent PDE 5 inhibitors
|
|
Author keywords
[No Author keywords available]
|
|
Indexed keywords
CGMP BINDING, CGMP SPECIFIC 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE;
CGMP-BINDING, CGMP-SPECIFIC 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE;
CYCLIC GMP PHOSPHODIESTERASE;
ENZYME INHIBITOR;
IMIDAZOLE DERIVATIVE;
TRIAZINE DERIVATIVE;
IMIDAZO[5,1 F][1,2,4]TRIAZIN 4(3H) ONE;
PHOSPHODIESTERASE;
PHOSPHODIESTERASE I;
PHOSPHODIESTERASE III;
PHOSPHODIESTERASE INHIBITOR;
PHOSPHODIESTERASE IV;
PHOSPHODIESTERASE V;
PURINE DERIVATIVE;
SILDENAFIL;
UNCLASSIFIED DRUG;
VARDENAFIL;
ANIMAL;
ARTICLE;
DRUG ANTAGONISM;
IC 50;
IMPOTENCE;
MALE;
METABOLISM;
PROTEIN BINDING;
RABBIT;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
ANIMAL MODEL;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG EFFICACY;
DRUG POTENCY;
DRUG SELECTIVITY;
DRUG SYNTHESIS;
ENZYME ACTIVITY;
ENZYME INHIBITION;
ERECTILE DYSFUNCTION;
IN VIVO STUDY;
NONHUMAN;
3',5'-CYCLIC-GMP PHOSPHODIESTERASE;
ANIMALS;
ENZYME INHIBITORS;
IMIDAZOLES;
IMPOTENCE;
INHIBITORY CONCENTRATION 50;
MALE;
PROTEIN BINDING;
RABBITS;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRIAZINES;
|
|
EID: 0037170832
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/S0960-894X(02)00030-6 Document Type: Article |
|
Times cited : (73)
|
|
References (42)
|
