Interaction between arachidonic acid and cAMP signaling pathways enhances steroidogenesis and StAR gene expression in MA-10 Leydig tumor cells

Molecular and Cellular Endocrinology

Volumn 188, Issue 1-2, 2002, Pages 55-63

  Wang, Xing Jia ^a   Dyson, Matthew T ^a   Mondillo, Carolina ^b   Patrignani, Zoraida ^b   Pignataro, Omar ^b   Stocco, Douglas M ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

Author keywords

Arachidonic acid; cAMP; StAR; Steroidogenesis

Indexed keywords

ARACHIDONIC ACID; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DEXAMETHASONE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHOLIPASE A2; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HORMONAL REGULATION; HORMONE SYNTHESIS; LEYDIG CELL TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEROID RELEASE; STEROIDOGENESIS;

EID: 0037169833     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(01)00748-1     Document Type: Article

References (27)

1. 2 in the regulation of luteinizing hormone-stimulated steroidogenesis in rat testis Leydig cells
2. Prostacyclin and steroidogenesis in goat ovarian cell types in vitro
3. Characterization of the promoter region of the mouse gene encoding the steroidogenic acute regulatory protein
4. The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)
5. Signal transduction involving cyclic AMP-dependent and cyclic AMP-independent mechanisms in the control of steroidogenesis
6. Release of arachidonic acid and the effects of corticosteroids on steroidogenesis in rat testis Leydig cells
7. A novel arachidonic acid-related thioesterase involved in acute steroidogenesis
8. Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis
9. Direct effect of arachidonic acid on protein kinase C and LH-stimulated steroidogenesis in rat Leydig cells; evidence for tonic inhibitory control of steroidogenesis by protein kinase C
10. Epidermal growth factor modulates intracellular arachidonic acid levels in MA-10 cultured Leydig tumor cells
11. Involvement of arachidonic acid and lipoxygenase pathway in mediating luteinizing hormone-induced testosterone synthesis in rat Leydig cells
12. Arachidonic acid release from rat Leydig cells depends on the presence of lutenizing hormone/human chorionic gonadotrophin receptors
13. Arachidonic acid metabolites by cytochrome P-450 dependent monooxygenase pathway in bovine adrenal fasciculata cells
14. Precolumn extraction and reversed-phase high-pressure liquid chromatography of prostaglandins and leukotrienes
15. Transcriptional regulation of the StAR gene
16. The relationship between progestins and gonadotrophins during the late luteal phase of the menstrual cycle in Rhesus monkeys
17. Arachidonic acid and its metabolites effects on testoterone production by rat Leydig cells
18. Tracking the role of a StAR in the sky of the new millennium
19. The use of genetic manipulation of MA-10 Leydig tumor cells to demonstrate the role of mitochondrial proteins in the acute regulation of steroidogenesis
20. Attenuation of cAMP-mediated responses in MA-10 Leydig tumor cells by genetic manipulation of a cAMP-phosphodiesterase
21. Arachidonic acid and prostaglandin E2 stimulate testosterone production by goldfish testis in vitro
22. Cyclic AMP and arachidonic acid: A tale of two pathways
23. Effect of truncated forms of the steroidogenic acute regulatory protein on intramitochodrial cholesterol transfer
24. The role of arachidonic acid on LH-stimulated steroidogenesis and steroidogenic acute regulatory protein accumulation in MA-10 mouse Leydig tumor cells
25. The role of arachidonic acid in steroidogenesis and steroidogenic acute regulatory (StAR) gene and protein expression
26. 15-Lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis
27. 2 activity