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European Journal of Pharmacology

Volumn 435, Issue 2-3, 2002, Pages 253-258

Weekly pulse therapy of methotrexate improves survival compared with its daily administration in MRL/lpr mice

(5) Asanuma, Yu a Nagai, Kasumi a Kato, Miyako a Sugiura, Hitoshi b Kawai, Shinichi a

a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE (Japan)

b KAWASAKI MUNICIPAL HOSPITAL (Japan)

Author keywords

Methotrexate; MRL lpr mouse; Myelosuppression; Pulse therapy weekly; Survival

Indexed keywords

DNA ANTIBODY; METHOTREXATE; RHEUMATOID FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHROPATHY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG PULSE THERAPY; DRUG TOXICITY; ERYTHROCYTE COUNT; KIDNEY DISEASE; LEUKOCYTE COUNT; LYMPHADENOPATHY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RHEUMATOID ARTHRITIS; SURVIVAL RATE;

ANIMALS; ANTIRHEUMATIC AGENTS; AUTOANTIBODIES; AUTOIMMUNITY; BLOOD CELL COUNT; BODY WEIGHT; GLOMERULONEPHRITIS; KIDNEY FUNCTION TESTS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHATIC DISEASES; MALE; METHOTREXATE; MICE; MICE, INBRED MRL LPR; PROTEINURIA; SURVIVAL ANALYSIS; UREA;

EID: 0037169166 PISSN: 00142999 EISSN: None Source Type: Journal
DOI: 10.1016/S0014-2999(01)01555-2 Document Type: Article

Times cited : (8)

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