Engineering-specific pharmacological binding sites for peptidyl inhibitors of potassium channels into KcsA

Biochemistry

Volumn 41, Issue 51, 2002, Pages 15369-15375

  Legros, Christian ^a,d   Schulze, Christian ^a   Garcia, Maria L ^b   Bougis, Pierre E ^c   Martin Eauclaire, Marie France ^c   Pongs, Olaf ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b MERCK RESEARCH LABORATORIES   (United States)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; ENZYME IMMOBILIZATION; ENZYME INHIBITION; ESCHERICHIA COLI; POTASSIUM; SURFACE PLASMON RESONANCE;

BINDING PROPERTIES;

BIOCHEMICAL ENGINEERING;

HONGOTOXIN; IODOTYROSINE; KALIOTOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; BINDING AFFINITY; CHANNEL GATING; DRUG BINDING SITE; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BACTERIAL PROTEINS; BINDING SITES; DELAYED RECTIFIER POTASSIUM CHANNELS; HUMANS; KV1.1 POTASSIUM CHANNEL; KV1.2 POTASSIUM CHANNEL; KV1.3 POTASSIUM CHANNEL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHENYLALANINE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SCORPION VENOMS; SURFACE PLASMON RESONANCE; TYROSINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; SCORPIONES;

EID: 0037168487     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026264a     Document Type: Article

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