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Volumn 277, Issue 8, 2002, Pages 5944-5951

ATPase domain of eukaryotic DNA topoisomerase II. Inhibition of ATPase activity by the anti-cancer drug bisdioxopiperazine and ATP/ADP-induced dimerization

(3) Hu, Tao a Sage, Harvey a Hsieh, Tao shih a

a DUKE UNIVERSITY MEDICAL CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSSLINKING; DIMERIZATION; DISSOCIATION; DNA; DRUG PRODUCTS; ENZYME INHIBITION; HYDROLYSIS;

SEDIMENTATION EQUILIBRIUM ANALYSIS;

ENZYMES;

2,3 BIS(3,5 DIOXO 1 PIPERAZINYL)BUTANE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); PIPERAZINE DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; EUKARYOTE; HUMAN; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CROSS-LINKING REAGENTS; DIMERIZATION; DNA GYRASE; DNA PRIMERS; DNA TOPOISOMERASES, TYPE II; DROSOPHILA; ENZYME INHIBITORS; HUMANS; KINETICS; PIPERAZINES; POLYMERASE CHAIN REACTION;

EUKARYOTA;

EID: 0037155222 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M111394200 Document Type: Article

Times cited : (52)

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