Entrapment of 6-thiophosphoryl-IMP in the active site of crystalline adenylosuccinate synthetase from Escherichia coli

Journal of Biological Chemistry

Volumn 272, Issue 24, 1997, Pages 15200-15205

  Poland, Bradley W ^a   Bruns, Christina ^a   Fromm, Herbert J ^a   Honzatko, Richard B ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; 6 THIOPHOSPHORYL IMP; ADENYLOSUCCINATE SYNTHASE; GUANOSINE DIPHOSPHATE; HADACIDIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ADENYLOSUCCINATE SYNTHASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; INOSINE MONOPHOSPHATE; LIGANDS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA;

EID: 0030972741     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.24.15200     Document Type: Article

References (31)

1. De Abreu, R. A. (1995) in Purine and Pyrimidine Metabolism in Man VIII (Sahota, A. & Taylor, M., eds) pp. 195-200, Plenum Publishing Corp., New York
2. Stayton, M. M., Rudolph, F. B. & Fromm, H. J. (1983) Curr. Top. Cell. Regul. 22, 103-141
3. Rudolph, F. B. & Fromm, H. J. (1969) J. Biol. Chem. 244, 3832-3839
4. Clark, S. W. & Rudolph, F. B. (1976) Biochim. Biophys. Acta 437, 87-93
5. Markham, D. G. & Reed, G. H. (1977) Arch. Biochem. Biophys. 184, 24-35
6. Markham, G. D. & Reed, G. H. (1978) J. Biol. Chem. 253, 6184-6189
7. Kaczka, E. A., Gitterman, C. O., Dulaney, E. L. & Folkers, K. (1962) Biochemistry 1, 340-343
8. Shigeura, H. T. (1967) in Antibiotics (Gottlieb, D. & Shaw, P., eds) pp. 451-456, Springer-Verlag New York Inc., New York
9. Lieberman, I. (1956) J. Biol. Chem. 223, 327-339
10. Fromm, H. J. (1958) Biochim. Biophys. Acta 29, 255-262
11. Bass, M. B., Fromm, H. J. & Rudolph, F. B. (1984) J. Biol. Chem. 259, 12330-12333
12. Cooper, B. F., Fromm, H. J. & Rudolph, F. B. (1986) Biochemistry 25, 7323-7327
13. Bass, M. B., Fromm, H. J. & Stayton, M. M. (1987) Arch. Biochem. Biophys. 256, 335-342
14. Silva, M. M., Poland, B. W., Hoffman, C. R., Fromm, H. J. & Honzatko, R. B. (1995) J. Mol. Biol. 254, 431-446
15. Poland, B. W., Fromm, H. J. & Honzatko, R. B. (1996) J. Mol. Biol. 264, 1013-1027
16. Howard, A. J., Nielsen, C. & Xuong, N. H. (1985) Methods Enzymol. 114, 452-472
17. Cambillau, C. & Horjales, E. (1987) J. Mol. Graphics 5, 174-177
18. Brünger, A. T. (1992) XPLOR, Version 3.1., Yale University Press, New Haven, CT
19. Engh, R. A. & Huber, R. (1991) Acta Crystallogr. Sec. A 47, 392-400
20. Bernardinelli, G., Tronchet, J. M. J. & Bizzozero, N. (1991) Z. Kristallog. 195, 135-138
21. Luzzati, V. (1962) Acta Crystallogr. 5, 802-810
22. Ramachandran, G. N., Ramakrishnan, C. & Sasisekharan, V. (1963) J. Mol. Biol. 7, 95-99
23. Poland, B. W., Silva, M. M., Serra, M. A., Cho, Y., Kim, K. H., Harris, E. M. S. & Honzatko, R. B. (1993) J. Biol. Chem. 268, 25334-25342
24. Poland, B. W., Hou, Z., Bruns, C., Fromm, H. J. & Honzatko, R. B. (1996) J. Biol. Chem. 271, 15407-15413
25. Poland, B. W., Lee, S.-F., Subramanian, M. V., Siehl, D. L., Anderson, R. J., Fromm, H. J. & Honzatko, R. B. (1996) Biochemistry 35, 15753-15759
26. Laskowski, R. A., Mac Arthur, M. W., Moss, D. S. & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
27. Kang, C., Poland, B. W., Gorrell, A., Honzatko, R. B. & Fromm, H. J. (1997) J. Biol. Chem. 272, 11881-11885
28. Spector, T., Jones, T. E. & Elion, G. B. (1979) J. Biol. Chem. 254, 8422-8426
29. Spector, T., Berens, R. L. & Marr, J. J. (1982) Biochem. Pharmacol. 31, 225-229
30. Porter, D. J. T., Rudie, N. G. & Bright, H. J. (1983) Arch. Biochem. Biophys. 225, 157-163
31. Miller, R. W. & Buchanan, J. M. (1962) J. Biol. Chem. 237, 485-490