Novel substituted 4-aminomethylpiperidines as potent and selective human β3-agonists. Part 1: Aryloxypropanolaminomethylpiperidines

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 20, 2002, Pages 2957-2961

  Steffan, Robert J ^a   Ashwell, Mark A ^a   Solvibile, William R ^a   Matelan, Edward ^a   Largis, Elwood ^a   Han, Stella ^a   Tillet, Jeffery ^a   Mulvey, Ruth ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOMETHYLPIPERIDINE; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; OXYPROPANOLAMINOMETHYLPIPERIDINE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; TRANSGENIC MOUSE;

ADRENERGIC BETA-AGONISTS; ANIMALS; CHO CELLS; CRICETINAE; HUMANS; INDICATORS AND REAGENTS; MICE; MICE, TRANSGENIC; PIPERIDINES; RECEPTORS, ADRENERGIC, BETA-3; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS MUSCULUS;

EID: 0037152534     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00607-8     Document Type: Article

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