The major conformational IgE-binding epitopes of hevein (Hev b6.02) are identified by a novel chimera-based allergen epitope mapping strategy

Journal of Biological Chemistry

Volumn 277, Issue 25, 2002, Pages 22656-22661

  Karisola, Piia ^a   Alenius, Harri ^a   Mikkola, Jari ^b   Kalkkinen, Nisse ^a   Helin, Jari ^a   Pentikäinen, Olli T ^a   Repo, Susanna ^b   Reunala, T Timo ^a,b   Turjanmaa, Kristiina ^a,b   Johnson, Mark S ^b   Palosuo, Timo ^a   Kulomaa, Markku S ^a  

^a Departments of Microbiology and Immunology   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; ENZYME INHIBITION; IMMUNOLOGY; PROTEINS;

MAPPING STRATEGY;

BIOCHEMISTRY;

ALLERGEN; AMINO ACID; ANTIMICROBIAL PROTEIN; CHIMERIC PROTEIN; EPITOPE; HEVEIN; IMMUNOGLOBULIN BINDING FACTOR; IMMUNOGLOBULIN E; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ALLERGY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIGEN RECOGNITION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOTHERAPY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

ADENOSINE MONOPHOSPHATE; ADOLESCENT; ADULT; AGED; ALLERGENS; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CHICKENS; DATABASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; FEMALE; HUMANS; IMMUNOGLOBULIN E; LECTINS; MALE; MIDDLE AGED; MODELS, MOLECULAR; PEPTIDE BIOSYNTHESIS; PLANT LECTINS; PLANT PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

AMARANTHUS; AMARANTHUS CAUDATUS;

EID: 0037151044     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M201076200     Document Type: Article

References (33)