Celiprolol inhibits mitogen-activated protein kinase and endothelin-1 and transforming growth factor-β1 gene in rats

European Journal of Pharmacology

Volumn 457, Issue 2-3, 2002, Pages 85-93

  Tsubokou, Yusuke ^a   Kobayashi, Naohiko ^a   Mita, Shin Ichiro ^a   Yoshida, Kohtaro ^a   Matsuoka, Hiroaki ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Adrenoceptor antagonist; Endothelin 1; Signal transduction; TGF 1 (transforming growth factor 1)

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; CELIPROLOL; COLLAGEN TYPE 1; DEOXYCORTICOSTERONE ACETATE; ENDOTHELIN A RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PREPROENDOTHELIN 1; PROTEIN C FOS; TRANSFORMING GROWTH FACTOR BETA1; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DEOXYCORTICOSTERONE; ENDOTHELIN 1; MESSENGER RNA; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART LEFT VENTRICLE; HEART PROTECTION; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR FIBROSIS; VASCULAR LESION; ANIMAL; BIOSYNTHESIS; BODY WEIGHT; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEART VENTRICLE; HEART VENTRICLE REMODELING; HEMODYNAMICS; METABOLISM; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; CELIPROLOL; DESOXYCORTICOSTERONE; ENDOTHELIN-1; GENE EXPRESSION REGULATION; HEART VENTRICLES; HEMODYNAMIC PROCESSES; HYPERTENSION; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; ORGAN SIZE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; VENTRICULAR REMODELING;

EID: 0037146862     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02648-1     Document Type: Article

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