-
1
-
-
0037146220
-
Potential use of imatinib in Ewing's sarcoma: Evidence for in vitro and in vivo activity
-
Merchant MS, Woo CW, Mackall CL, Thiele CJ. Potential use of imatinib in Ewing's sarcoma: evidence for in vitro and in vivo activity. J Natl Cancer Inst 2002;94:1673-9.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1673-1679
-
-
Merchant, M.S.1
Woo, C.W.2
Mackall, C.L.3
Thiele, C.J.4
-
2
-
-
0033634872
-
The metastatic ability of Ewing's sarcoma cells is modulated by stem cell factor and by its receptor c-kit
-
Landuzzi L, De Giovanni C, Nicoletti G, Rossi I, Ricci C, Astolfi A, et al. The metastatic ability of Ewing's sarcoma cells is modulated by stem cell factor and by its receptor c-kit. Am J Pathol 2000;157:2123-31.
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 2123-2131
-
-
Landuzzi, L.1
De Giovanni, C.2
Nicoletti, G.3
Rossi, I.4
Ricci, C.5
Astolfi, A.6
-
3
-
-
0032055562
-
c-kit is expressed in soft tissue sarcoma of neuroectodermic origin and its ligand prevents apoptosis of neoplastic cells
-
Ricotti E, Fagioli F, Garelli E, Linari C, Crescenzio N, Horenstein AL, et al. c-kit is expressed in soft tissue sarcoma of neuroectodermic origin and its ligand prevents apoptosis of neoplastic cells. Blood 1998;91:2397-405.
-
(1998)
Blood
, vol.91
, pp. 2397-2405
-
-
Ricotti, E.1
Fagioli, F.2
Garelli, E.3
Linari, C.4
Crescenzio, N.5
Horenstein, A.L.6
-
4
-
-
0034254249
-
Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor
-
Heinrich MC, Griffith DJ, Druker BJ, Wait CL, Ott KA, Zigler AJ. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood 2000;96:925-32.
-
(2000)
Blood
, vol.96
, pp. 925-932
-
-
Heinrich, M.C.1
Griffith, D.J.2
Druker, B.J.3
Wait, C.L.4
Ott, K.A.5
Zigler, A.J.6
-
5
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker BJ, Lydon NB. Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J Clin Invest 2000;105:3-7.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
6
-
-
0036352770
-
c-KIT-expressing Ewing tumour cells are insensitive to imatinib mesylate (STI571)
-
Hotfilder M, Lanvers C, Jurgens H, Boos J, Vormoor J. c-KIT-expressing Ewing tumour cells are insensitive to imatinib mesylate (STI571). Cancer Chemother Pharmacol 2002;50:167-9.
-
(2002)
Cancer Chemother. Pharmacol.
, vol.50
, pp. 167-169
-
-
Hotfilder, M.1
Lanvers, C.2
Jurgens, H.3
Boos, J.4
Vormoor, J.5
-
7
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996;2:561-6.
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
-
9
-
-
0035899418
-
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications
-
Tuveson DA, Willis NA, Jacks T, Griffin JD, Singer S, Fletcher CD, et al. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene 2001;20:5054-8.
-
(2001)
Oncogene
, vol.20
, pp. 5054-5058
-
-
Tuveson, D.A.1
Willis, N.A.2
Jacks, T.3
Griffin, J.D.4
Singer, S.5
Fletcher, C.D.6
-
10
-
-
85112384821
-
STI571 inhibits the kinase activity of wild type and juxtamembrane c-kit mutants but not the exon 17 D816V mutation associated with mastocytosis
-
Heinrich MC, Wait CL, Yee KW, Griffith DJ. STI571 inhibits the kinase activity of wild type and juxtamembrane c-kit mutants but not the exon 17 D816V mutation associated with mastocytosis. Blood 2000;96:173b.
-
(2000)
Blood
, vol.96
-
-
Heinrich, M.C.1
Wait, C.L.2
Yee, K.W.3
Griffith, D.J.4
-
11
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002;347:472-80.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
von Mehren, M.2
Blanke, C.D.3
Van den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
-
12
-
-
0003222976
-
KIT mutational status predicts response to STI571 in patients with metastatic gastrointestinal stromal tumors (GISTs)
-
Heinrich MC, Corless CL, Blanke CD, Demetri GD, Joensuu H, von Mehren M, et al. KIT mutational status predicts response to STI571 in patients with metastatic gastrointestinal stromal tumors (GISTs). Proc ASCO 2002;21:2a.
-
(2002)
Proc. ASCO
, vol.21
-
-
Heinrich, M.C.1
Corless, C.L.2
Blanke, C.D.3
Demetri, G.D.4
Joensuu, H.5
von Mehren, M.6
-
14
-
-
0034693799
-
The protein tyrosine kinase family of the human genome
-
Robinson DR, Wu YM, Lin SF. The protein tyrosine kinase family of the human genome. Oncogene 2000;19:5548-57.
-
(2000)
Oncogene
, vol.19
, pp. 5548-5557
-
-
Robinson, D.R.1
Wu, Y.M.2
Lin, S.F.3
-
15
-
-
0037018763
-
Treatment of hypereosinophilic syndrome with imatinib mesilate
-
Gleich GJ, Leiferman KM, Pardanani A, Tefferi A, Butterfield JH. Treatment of hypereosinophilic syndrome with imatinib mesilate. Lancet 2002;359:1577-8.
-
(2002)
Lancet
, vol.359
, pp. 1577-1578
-
-
Gleich, G.J.1
Leiferman, K.M.2
Pardanani, A.3
Tefferi, A.4
Butterfield, J.H.5
-
16
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344:1031-7.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
-
17
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Fernandes Reese S, Ford JM, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001;344:1038-42.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Fernandes Reese, S.5
Ford, J.M.6
-
18
-
-
0035960428
-
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase I study
-
van Oosterom AT, Judson I, Verweij J, Stroobants S, Donato di Paola E, Dimitrijevic S, et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 2001;358:1421-3.
-
(2001)
Lancet
, vol.358
, pp. 1421-1423
-
-
van Oosterom, A.T.1
Judson, I.2
Verweij, J.3
Stroobants, S.4
Donato di Paola, E.5
Dimitrijevic, S.6
-
19
-
-
0001818280
-
Clinical investigation of the pharmacokinetic/pharmacodynamic relationship for Glivec (STI571): A novel inhibitor of signal transduction
-
Peng B, Hayes M, Racine-Poon A, Druker BJ, Talpaz M, Sawyers CL, et al. Clinical investigation of the pharmacokinetic/pharmacodynamic relationship for Glivec (STI571): a novel inhibitor of signal transduction. Proc ASCO 2001;20:280a.
-
(2001)
Proc ASCO
, vol.20
-
-
Peng, B.1
Hayes, M.2
Racine-Poon, A.3
Druker, B.J.4
Talpaz, M.5
Sawyers, C.L.6
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