ST-segment elevation and ventricular fibrillation without coronary spasm by intracoronary injection of acetylcholine and/or ergonovine maleate in patients with Brugada syndrome

Journal of the American College of Cardiology

Volumn 40, Issue 10, 2002, Pages 1841-1847

  Noda, Takashi ^a   Shimizu, Wataru ^a   Taguchi, Atsushi ^a   Satomi, Kazuhiro ^a   Suyama, Kazuhiro ^a   Kurita, Takashi ^a   Aihara, Naohiko ^a   Kamakura, Shiro ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ERGOMETRINE MALEATE;

ACTION POTENTIAL; ADULT; ANGIOCARDIOGRAPHY; ARTICLE; BRUGADA SYNDROME; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY SPASM; ELECTROCARDIOGRAPHY; FEMALE; HEART MUSCLE ISCHEMIA; HEART RIGHT BUNDLE BRANCH BLOCK; HEART VENTRICLE FIBRILLATION; HUMAN; INTRACORONARY INFUSION; MALE; PRIORITY JOURNAL; RIGHT CORONARY ARTERY; ST SEGMENT ELEVATION; SUDDEN DEATH; VAGUS NERVE STIMULATION; VASOSPASM;

ACETYLCHOLINE; ADULT; AGED; BUNDLE-BRANCH BLOCK; CORONARY VASOSPASM; CORONARY VESSELS; DEATH, SUDDEN, CARDIAC; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; ERGONOVINE; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; INJECTIONS, INTRAVENOUS; JAPAN; MALE; MIDDLE AGED; SYNDROME; VASODILATOR AGENTS; VENTRICULAR FIBRILLATION;

EID: 0037145916     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(02)02494-4     Document Type: Article

References (25)

1. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992;20:1391-6.
2. 3: A marker for sudden death in patients without demonstrable structural heart disease. Circulation 1998;97:457-60.
3. Antzelevitch C. The Brugada syndrome. J Cardiovasc Electrophysiol 1998;9:513-6.
4. Gussak I, Antzelevitch C, Bjerregaard P, Towbin JA, Chaitman BR. The Brugada syndrome: Clinical, electrophysiological and genetic aspects. J Am Coll Cardiol 1999;33:5-15.
5. Alings M, Wilde A. 'Brugada' syndrome: Clinical data and suggested pathophysiological mechanism. Circulation 1999;99:666-73.
6. Miller DD, Waters DD, Szlachcic J, Theroux P. Clinical characteristics associated with sudden death in patients with variant angina. Circulation 1982;66:588-92.
7. Yasue H, Horio Y, Nakamura N, et al. Induction of coronary, artery spasm by acetylcholine in patients with variant angina: Possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. Circulation 1986;74:955-63.
8. Macalpin RN. Cardiac arrest and sudden unexpected death in variant angina: Complications of coronary spasm that can occur in the absence of severe organic coronary stenosis. Am Heart J 1993;125:1011-7.
9. Petera RHJ, Wever EFD, Hauer RNW, Robles de Medina EO. Low prevalence of coronary artery spasm in patients with normal coronary angiograms and unexplained ventricular fibrillation. Eur Heart J 1998;19:1070-4.
10. Itoh E, Suzuki K, Tanabe Y. A case of vasospastic angina presenting Brugada-type ECG abnormalities. Jpn Circ J 1999;63:493-5.
11. Chinushi M, Kuroe Y, Ito E, Tagawa M, Aizawa Y. Vasospastic angina accompanied by Brugada-type electrocardiographic abnormalities. J Cardiovasc Electrophysiol 2001;12:108-11.
12. Yan GX, Antzelevitch C. Cellular basis for the electrocardiographic J wave. Circulation 1996;93:372-9.
13. Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST segment elevation. Circulation 1999;100:1660-6.
14. Litovsky SH, Antzelevitch C. Transient outward current prominent in canine ventricular epicardium but not endocardium. Circ Res 1988; 62:116-26.
15. Shimizu W, Matsuo K, Takagi M, et al. Body surface distribution and response to drugs of ST segment elevation in the Brugada syndrome: Clinical implication of 87-lead body surface potential mapping and its application to 12-lead electrocardiograms. J Cardiovasc Electrophysiol 2000;11:396-404.
16. Shimizu W, Antzelevitch C, Suyama K, et al. Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. J Cardiovasc Electrophysiol 2000; 11:1320-9.
17. Miyazaki T, Mitamura H, Miyoshi S, Soejima K, Aizawa Y, Ogawa S. Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome. J Am Coll Cardiol 1996;27:1061-70.
18. Kasanuki H, Ohnishi S, Ohtuka M, et al. Idiopathic ventricular fibrillation induced with vagal activity in patients without obvious heart disease. Circulation 1997;95:2277-85.
19. Matsuo K, Kurita T, Inagaki M, et al. The circadian pattern of the development of ventricular fibrillation in patients with Brugada syndrome. Eur Heart J 1999;20:465-70.
20. Priori SG, Napolitano C, Gasparini M, et al. Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: A prospective evaluation of 52 families. Circulation 2000; 102:2509-15.
21. Brugada P, Brugada J, Antzelevitch C, et al. Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts. Circulation 2001;101:510-5.
22. Shimizu W, Aiba T, Kurita T, Kamakura S. Paradoxical abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevation. J Cardiovasc Electrophysiol 2001;12:1418-21.
23. Kanda M, Shimizu W, Matsuo K, et al. Electrophysiologic characteristics and implication of induced ventricular fibrillation in symptomatic patients with Brugada syndrome. J Am Coll Cardiol 2002;39:1799-805.
24. Krishnan SC, Antzelevitch C. Flecainide-induced arrhythmia in canine ventricular epicardium: Phase 2 reentry? Circulation 1993; 87:562-72.
25. Lukas A, Antzelevitch C. Phase 2 reentry as a mechanism of initiation of circus movement reentry in canine epicardium exposed to simulated ischemia. Cardiovasc Res 1996;32:593-603.