Heregulin inhibits proliferation via ERKs and phosphatidyl-inositol 3-kinase activation but regulates urokinase plasminogen activator independently of these pathways in metastatic mammary tumor cells

International Journal of Cancer

Volumn 100, Issue 6, 2002, Pages 642-653

  Puricelli, Lydia ^a   Proiettii, Cecilia J ^b   Labriola, Leticia ^c   Salatino, Mariana ^b   Balañá, María E ^d   Ghiso, Julio Aguirre ^a   Lupu, Ruth ^b   Pignataro, Omar P ^a   Charreau, Eduardo H ^c   De Joffé, Elisa Bal Kier ^b   Elizalde, Patricia V ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

Author keywords

ErbB receptors; ERKs; Heregulin; Metastatic mammary tumors; Phosphatidylinositol 3 kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GELATINASE B; MESSENGER RNA; MONOCLONAL ANTIBODY; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT HEREGULIN BETA1; STAT PROTEIN; UNCLASSIFIED DRUG; UROKINASE; WORTMANNIN;

ANIMAL CELL; ARTICLE; BREAST TUMOR; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CELL MOVEMENT; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MATRIX METALLOPROTEINASE 9; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM METASTASIS; NEUREGULIN-1; PHENOTYPE; PHOSPHORYLATION; PRECIPITIN TESTS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; RIBONUCLEASES; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR CELLS, CULTURED; URINARY PLASMINOGEN ACTIVATOR;

EID: 0037143784     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10533     Document Type: Article

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