Identification of potent and selective oxytocin antagonists. Part 1: Indole and benzofuran derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 10, 2002, Pages 1399-1404

  Wyatt, Paul G ^a   Foster, Alison ^a   Livermore, David G ^a   Mordaunt, Jackie E ^a   Scicinski, Jan ^a   Allen, Michael J ^a   Chilcott, Josie ^b   Woollard, Patrick M ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GLAXOSMITHKLINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 [1 [4 (1 ACETYL 4 PIPERIDINYLOXY) 2 METHOXYBENZOYL] 4 PIPERIDINYL]BENZ[D][1,3]OXAZIN 2 ONE; BENZOFURAN DERIVATIVE; INDOLE DERIVATIVE; OXYTOCIN; OXYTOCIN ANTAGONIST; OXYTOCIN RECEPTOR; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS;

ANIMALS; BENZOFURANS; BIOLOGICAL AVAILABILITY; DOGS; DRUG DESIGN; HUMANS; INDOLES; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OXYTOCIN; RECEPTORS, OXYTOCIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037140886     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00159-2     Document Type: Article

References (16)