Modulation of Oxidant Stress in Vivo in Chronic Cigarette Smokers

Circulation

Volumn 94, Issue 1, 1996, Pages 19-25

  Reilly, Murdeach ^a   Delanty, Norman ^a   Lawson, John A ^a   FitzGerald, Garret A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

8 epi PGF2 ; Free radicals; Isoprostanes; Prostaglandins; Smoking

Indexed keywords

11 DEHYDRO THROMBOXANE B2; 11-DEHYDRO-THROMBOXANE B2; 8 EPI PROSTAGLANDIN F2ALPHA; 8-EPI-PROSTAGLANDIN F2ALPHA; ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; DRUG DERIVATIVE; ISOPROSTANE DERIVATIVE; NICOTINE; PROSTAGLANDIN F2 ALPHA; THROMBOXANE B2;

ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DOSE RESPONSE; DRUG EFFECT; HUMAN; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; MIDDLE AGED; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL; SMOKING; URINE;

ADMINISTRATION, CUTANEOUS; ADOLESCENT; ADULT; ANTIOXIDANTS; ASCORBIC ACID; ASPIRIN; CROSS-SECTIONAL STUDIES; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; F2-ISOPROSTANES; HUMANS; MIDDLE AGED; NICOTINE; OXIDATIVE STRESS; SMOKING; THROMBOXANE B2; VITAMIN E;

EID: 0030187952     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.1.19     Document Type: Article

References (56)

1. US Department of Health and Human Servies. The Health Consequences of Smoking: 25 Years of Progress. A Report of the Surgeon General. US Department of Health and Human Services Public Health Service, Centers for Disease Control, Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. Washington, DC: DHHS publication (CDC) 89-8411; 1989.
2. Peto R, Lopez AD, Boreham J, Thun M, Heath C Jr. Mortality from tobacco in developed countries: indirect estimates from national vital statistics. Lancet. 1992;339:1268-1278
3. Kita T, Yokode M, Arai H, Hyama M, Ueda Y, Ueyama K, Narumiya S. Cigarette smoke, LDL and cholesteryl ester accumulation in macrophages. Ann N Y Acad Sci. 1993;686:91-97
4. Frei B, Forte TM, Ames BN, Cross CCE. Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Biochem J. 1991;277: 133-138.
5. Lehr HA, Kress E, Menger MD, Friedl HP, Hubner C, Arfors KE, Messmer KE. Cigarette smoke elicits leukocyte adhesion to endothelium in hamsters: inhibition by CuZn-SOD. Free Radic Biol Med. 1993;14:573-581.
6. Phillips DH, Hewer A, Martin CN, Garner RC, King MM. Correlation of DNA adduct level in human lung with cigarette smoking. Nature. 1988;366:790-792.
7. Grinberg-Funes RA, Singh VN, Perera FP, Bell DA, Young TL, Dickey C, Wang LW, Santella RM. Polycyclic aromatic hydrocarbon-DNA adducts in smokers and their relationship to micronutrient levels and the glutathione-S-transferase M1 genotype. Carcinogenesis. 1994;15:2449-2454.
8. Salvemini D, Botting R. Modulation of platelet function by free radicals and free-radical scavengers. Trends Pharmacol Sci. 1993;14: 36-42.
9. Steinberg D. Antioxidants and atherosclerosis. Circulation. 1991;84: 1420-1425.
10. Halliwell B, Chirico S. Lipid peroxidation: its mechanism, measurement and significance. Am J. Clin Nutr. 1993;57(suppl): 715S-725S.
11. Holley AE, Cheeseman KH. Measuring free radical reactions in vivo. Br Med Bull. 1992;49:494-505.
12. Dujovne CA, Harris WS, Colle Gerrond LL, Fan J, Muzio F. Comparison of effects of prohucol versus vitamin E on ex vivo oxidation susceptibility of lipoproteins in hyperlipoproteinemia. Am J Cardiol. 1994;74:38-42.
13. Janzen EG. Spin trapping and associated vocabulary. Free Radic Res Commun. 1990;10:63-68.
14. Gutteridge JMC. Aspects to consider when detecting and measuring lipid peroxidation. Free Radic Res Commun. 1986;1:173-184.
15. Holley AE, Slater TF. Measurement of lipid hydroperoxides in normal human blood plasma using HPLC-chemiluminescence linked to a diode array detector for measuring conjugated dienes. Free Radic Res Commun. 1991;15:51-63.
16. Morrow JD, Harris TM, Roberts LJ II. Non-cyclooxygenase oxidative formation of a series of novel prostaglandins: analytical ramifications for measurements of eicosanoids. Anal Biochem. 1990;184:1-10.
17. Morrow JD, Hill KE, Burk RF, Nammour TM, Badr KF, Roberts LJ II. A series of prostaglandin F2 like compounds are produced in vivo in humans by a non-cyclooxygenase free radical catalyzed mechanism. Proc Natl Acad Sci U S A. 1990;87:9383-9387.
18. 2-isoprostanes) in smokers. N Engl J Med. 1995;332:1198-1203.
19. 2-isosprostane receptors on rat vascular smooth muscle cells. Am J Physiol. 1993;264: 1619-1624.
20. 2α. J Biol Chem. 1995;270:9800-9808.
21. Nowak J, Murray JJ, Oates JA, FitzGerald GA. Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes. Circulation. 1987;76: 6-14.
22. Lassila R, Seyberth HW, Haspanen A, Schweer HW, Koskenvuo M, Laustiola KE. Vasoactive and atherogcnic effects of cigarette smoking: a study of monozygotic twins discordant for smoking. Br Med J. 1988;297:955-957.
23. 2α and utility for quantitative mass spectrometry. Anal Biochem. 1981;111:115-121.
24. 2 metabolites in humans. Thromb Res. 1987;47:647-656.
25. Knapp HR, Healy C, Lawson J, FitzGerald GA. Effects of low-dose aspirin on endogenous eicosanoid formation in normal and atherosclerotic men. Thromb Res. 1988;50:377-386.
26. Perkins SL, Livesey JF, Escares EA, Belcher JM, Dudley DK. High- performance liquid chromatographic method compared with a modified radioimmunoassay of cotinine in plasma. Clin Chem. 1991;37:1989-1993.
27. Morrow JD, Minton TA, Mukundan CR, Campbell MD, Zackert WE, Daniel VC, Badr KF, Roberts LJ II. Free radical-induced generation of isoprostanes in vivo: evidence for the formation of D-ring and E-ring isoprostanes. J Biol Chem. 1994;269:4317-4326.
28. Harrison KA, Murphy RC. Isoleukotrienes: biologically active free radical products of lipid peroxidation. J Biol Chem. 1995;270: 17273-17278.
29. 2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci U S A. 1992;89: 10721-10725.
30. 2α, in rabbit lung in situ. Am J Physiol. 1992;263:H660-H663.
31. 2α is not modulated by thromboxane receptor isoforms. J Biol Chem. In press.
32. 2 receptors in human platelets. J Pharmacol Exp Ther. 1994;270:1192-1196.
33. 2α. J Pharmacol Exp Ther. 1995;275:94-100.
34. Benowitz NL, Jacob P. Metabolism, pharmacokinetics and pharmacodynamics of nicotine in man. In: Martin RW, VanLoon GR, Iwamoto ET, Davis L, eds. Advances in Behavior Biology: Tobacco Smoking and Nicotine. New York, NY: Plenum Press; 1987;357-373.
35. Cosgrove JP, Borish ET, Church DF, Pryor WA. The metal mediated formation of hydroxyl radicals by aqueous extracts of cigarette tar. Biochem Biophys Res Commun. 1985;132:390-396.
36. Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect. 1985;64: 111-126.
37. Pryor WA, Stone K. Oxidants in cigarette smoke: radicals, hydrogen peroxide, peroxynitrate and peroxynitrite. Ann N Y Acad Sci. 1993;686:12-27.
38. 2 receptors. J Clin Invest. 1992;90:136-141.
39. Roth GJ, Majerus PW. The mechanism of the effect of aspirin on platelets, I: acetylation of a particulate fraction protein. J Clin Invest. 1975;56:624-632.
40. DeWitt DL, Smith WL. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci U S A. 1988;85: 1412-1416.
41. Patrono C, Ciabattoni G, Pugliesse F, Pierucci A, Blair IA, FitzGerald GA. Estimated rate of thromboxane secretion into the circulation of normal man. J Clin Invest. 1986;77:590-594.
42. 2 biosynthesis in cardiovascular disease. Circulation. 1983;67:1174-1177.
43. 2 as a parameter of thromboxane production. Prostaglandin. 1986;31:413-444.
44. Takenaha Y, Miki M, Yasuda H, Mino M. The effect of α-tocopherol as an antioxidant on the oxidation of membrane protein thiols induced by free radicals generated in different sites. Arch Biochem Biophys. 1991;285:344-350.
45. Frei B. Ascorbic acid protects lipids in human plasma and low- density lipoprotein against oxidative damage. Am J Clin Nutr. 1991; 54:1113S-1118S.
46. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effects of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330:1029-1035.
47. Greenberg ER, Baron JA, Tosteson TD, Freeman DH, Beck GJ, Bond JH, Colacchio TA, Coller JA, Frankl HD, Haile RW, Mandel JS, Nierenberg DW, Rothstein R, Snover DC, Stevens MM, Summers RW, van Stolk RU, for the Polyp Prevention Study Group. A clinical trial of antioxidant vitamins to prevent colorectal adenoma. N Engl J Med. 1994;331:141-147.
48. Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med. 1993;328:1444-1449.
49. Rimm EB, Stamfer MJ, Asherio A, Giovannuci E, Colditz GA, Willett WC. Vitamin E consumption and the risk of coronary disease in men. N Engl J Med. 1993;328:1450-1456.
50. Hertog MJL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993;324:1007-1011.
51. Schectman G, Byrd JC, Gruchow HW. The influence of smoking on vitamin C status in adults. Am J Public Health. 1989;79:158-162.
52. Niki E. Action of ascorbic acid as a scavenger of active and stable oxygen radicals. Am J Clin Nutr. 1991;54:1119S-1124S.
53. Buettner GR. The pecking order of free radicals and antioxidants: lipid peroxidation, α-tocopherol, and ascorbate. Arch Biochem Biophys. 1993;300:535-543.
54. VanDerWerken B, Hopkins R, Stegner J, Weinberg R. Effect of combined vitamin E and C treatment on high density lipoprotein plasma levels and oxidation in cigarette smokers. Circulation. 1995; 92(suppl I):I-352. Abstract.
55. Loft S, Astrup A, Buemann B, Poulsen HE. Oxidative DNA damage correlates with oxygen consumption in humans. FASEB J. 1994;8:534-537.
56. Delanty N, Reilly M, Pratico D, Fitzgerald DJ, Lawson J, FitzGerald GA. Specific analysis of an isoeicosanoid as an index of oxidant stress in vivo. Br J Clin Pharmacol. In press.