Novel stereocontrolled addition of allylmetal reagents to α-imino esters: Efficient synthesis of chiral tetrahydroquinoline derivatives

Journal of Organic Chemistry

Volumn 67, Issue 21, 2002, Pages 7319-7328

  Di Fabio, Romano ^a   Alvaro, Giuseppe ^a   Bertani, Barbara ^a   Donati, Daniele ^a   Giacobbe, Simone ^a   Marchioro, Carla ^a   Palma, Carlotta ^a   Lynn, Sean M ^a,b  

^a GSK   (Italy)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYLATION REACTION; STEREODIFFERENTIATION REACTIONS;

ADDITION REACTIONS; AMINO ACIDS; CHEMICAL BONDS; ESTERS; STEREOCHEMISTRY; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

DRUG PRODUCTS;

ALLYL COMPOUND; ESTER DERIVATIVE; GLYCINE; LACTIC ACID DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; QUINOLINE DERIVATIVE; REAGENT; TETRAHYDROQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHEMICAL BOND; CHEMICAL REACTION; CHIRALITY; CYCLIZATION; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

ALLYL COMPOUNDS; CATALYSIS; IMINES; INDICATORS AND REAGENTS; INDOLES; METALS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PYRROLES; QUINOLONES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037131374     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020327d     Document Type: Article

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