메뉴 건너뛰기




Volumn 298, Issue 1, 2002, Pages 9-19

Transcriptional repression of the RET proto-oncogene by a mitogen activated protein kinase-dependent signalling pathway

Author keywords

Early growth response gene 1; Medullary thyroid carcinoma; Sephacryl and phosphocellulose protein 1

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN RET; SEPHACRYL AND PHOSPHOCELLULOSE PROTEIN 1; TRANSCRIPTION FACTOR EGR 1; UNCLASSIFIED DRUG;

EID: 0037130936     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00919-8     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi D.R., Cuenda A., Cohen P., Dudley D.T., Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:1995;27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 2
    • 0034601709 scopus 로고    scopus 로고
    • Sp1 and Sp3 transactivate the RET proto-oncogene promoter
    • Andrew S.D., Delhanty P.J., Mulligan L.M., Robinson B.G. Sp1 and Sp3 transactivate the RET proto-oncogene promoter. Gene. 256:2000;283-291.
    • (2000) Gene , vol.256 , pp. 283-291
    • Andrew, S.D.1    Delhanty, P.J.2    Mulligan, L.M.3    Robinson, B.G.4
  • 3
    • 0030273360 scopus 로고    scopus 로고
    • High Sp1/Sp3 rations in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter
    • Apt D., Watts Robin M., Suske G., Bernard H.-U. High Sp1/Sp3 rations in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter. Virology. 224:1996;281-291.
    • (1996) Virology , vol.224 , pp. 281-291
    • Apt, D.1    Watts Robin, M.2    Suske, G.3    Bernard, H.-U.4
  • 4
    • 0036156038 scopus 로고    scopus 로고
    • Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: Induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene
    • Bahouth S.W., Beauchamp M.J., Vu K.N. Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene. Mol. Pharmacol. 61:2002;379-390.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 379-390
    • Bahouth, S.W.1    Beauchamp, M.J.2    Vu, K.N.3
  • 7
    • 0027182018 scopus 로고
    • Detection and characterisation of cellular Egr-1 binding to its recognition site
    • Cao X.M., Mahendran R., Guy G.R., Tan Y.H. Detection and characterisation of cellular Egr-1 binding to its recognition site. J. Biol. Chem. 268:1993;16949-16957.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16949-16957
    • Cao, X.M.1    Mahendran, R.2    Guy, G.R.3    Tan, Y.H.4
  • 8
    • 0029006925 scopus 로고
    • Ret gene silencing is associated with Raf-1-induced medullary thyroid carcinoma cell differentiation
    • Carson E.B., McMahon M., Baylin S.B., Nelkin B.D. Ret gene silencing is associated with Raf-1-induced medullary thyroid carcinoma cell differentiation. Cancer Res. 55:1995;2048-2052.
    • (1995) Cancer Res. , vol.55 , pp. 2048-2052
    • Carson, E.B.1    McMahon, M.2    Baylin, S.B.3    Nelkin, B.D.4
  • 9
    • 0032560857 scopus 로고    scopus 로고
    • Post-transcriptional silencing of Ret occurs, but is not required, during Raf-1 mediated differentiation of medullary thyroid carcinoma cells
    • Carsonwalter E.B., Smith D.P., Ponder B.A.J., Baylin S.B., Nelkin B.D. Post-transcriptional silencing of Ret occurs, but is not required, during Raf-1 mediated differentiation of medullary thyroid carcinoma cells. Oncogene. 17:1998;367-376.
    • (1998) Oncogene , vol.17 , pp. 367-376
    • Carsonwalter, E.B.1    Smith, D.P.2    Ponder, B.A.J.3    Baylin, S.B.4    Nelkin, B.D.5
  • 10
    • 0004105358 scopus 로고    scopus 로고
    • P53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis
    • de Belle I., Huang R.P., Fan Y., Liu C., Mercola D., Adamson E.D. p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis. Oncogene. 18:1999;3633-3642.
    • (1999) Oncogene , vol.18 , pp. 3633-3642
    • De Belle, I.1    Huang, R.P.2    Fan, Y.3    Liu, C.4    Mercola, D.5    Adamson, E.D.6
  • 11
    • 0022999360 scopus 로고
    • Cyclic AMP and phorbol esters separately induce growth inhibition, calcitonin secretion, and calcitonin gene transcription in cultured human medullary thyroid carcinoma
    • deBustros A., Baylin S.B., Levine M.A., Nelkin B.D. Cyclic AMP and phorbol esters separately induce growth inhibition, calcitonin secretion, and calcitonin gene transcription in cultured human medullary thyroid carcinoma. J. Biol. Chem. 261:1986;8036-8041.
    • (1986) J. Biol. Chem. , vol.261 , pp. 8036-8041
    • DeBustros, A.1    Baylin, S.B.2    Levine, M.A.3    Nelkin, B.D.4
  • 12
    • 0035019560 scopus 로고    scopus 로고
    • Acid-labile subunit regulation during the early stages of liver regeneration: Implications for glucoregulation
    • Delhanty P.J., Scott C.D., Babu S., Baxter R.C. Acid-labile subunit regulation during the early stages of liver regeneration: implications for glucoregulation. Am. J. Physiol. Endocrinol. Metab. 280:2001;E287-E295.
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.280
    • Delhanty, P.J.1    Scott, C.D.2    Babu, S.3    Baxter, R.C.4
  • 13
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 14
    • 0035379644 scopus 로고    scopus 로고
    • Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation
    • Fanton C.P., McMahon M., Pieper R.O. Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation. J. Biol. Chem. 276:2001;18871-18877.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18871-18877
    • Fanton, C.P.1    McMahon, M.2    Pieper, R.O.3
  • 15
    • 0027183967 scopus 로고
    • A novel repression module, an extensive activation domain, and a bipartite nuclear localisation signal defined in the immediate-early transcription factor Egr-1
    • Gashler A.L., Swaminathan S., Sukhatme V.P. A novel repression module, an extensive activation domain, and a bipartite nuclear localisation signal defined in the immediate-early transcription factor Egr-1. Mol. Cell. Biol. 13:1993;4556-4571.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4556-4571
    • Gashler, A.L.1    Swaminathan, S.2    Sukhatme, V.P.3
  • 16
    • 0033729031 scopus 로고    scopus 로고
    • Multiple endocrine neoplasia type 2 and RET: From neoplasia to neurogenesis
    • Hansford J.R., Mulligan L.M. Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis. J. Med. Genet. 37:2000;817-827.
    • (2000) J. Med. Genet. , vol.37 , pp. 817-827
    • Hansford, J.R.1    Mulligan, L.M.2
  • 17
    • 0024083068 scopus 로고
    • Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated
    • Holler M., Westin G., Jiricny J., Schaffner W. Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev. 2:1988;1127-1135.
    • (1988) Genes Dev. , vol.2 , pp. 1127-1135
    • Holler, M.1    Westin, G.2    Jiricny, J.3    Schaffner, W.4
  • 18
    • 0028862848 scopus 로고
    • Egr-1 negatively regulates human tumor cell growth via the Dna-binding domain
    • Huang R.P., Liu C.T., Fan Y., Mercola D., Adamson E.D. Egr-1 negatively regulates human tumor cell growth via the Dna-binding domain. Cancer Res. 55:1995;5054-5062.
    • (1995) Cancer Res. , vol.55 , pp. 5054-5062
    • Huang, R.P.1    Liu, C.T.2    Fan, Y.3    Mercola, D.4    Adamson, E.D.5
  • 19
    • 0030837544 scopus 로고    scopus 로고
    • Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation
    • Huang R.P., Fan Y., Debelle I., Niemeyer C., Gottardis M.M., Mercola D., Adamson E.D. Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation. Int. J. Cancer. 72:1997;102-109.
    • (1997) Int. J. Cancer , vol.72 , pp. 102-109
    • Huang, R.P.1    Fan, Y.2    Debelle, I.3    Niemeyer, C.4    Gottardis, M.M.5    Mercola, D.6    Adamson, E.D.7
  • 20
    • 0026509983 scopus 로고
    • Identification and analysis of the ret proto-oncogene promoter region in neuroblastoma cell lines and medullary thyroid carcinomas from MEN2 A patients
    • Itoh F., Ishizaka Y., Tahira T., Yamamoto M., Miya A., Imai K., Yachi A., Takai S., Sugimura T., Nagao M. Identification and analysis of the ret proto-oncogene promoter region in neuroblastoma cell lines and medullary thyroid carcinomas from MEN2 A patients. Oncogene. 7:1992;1201-1206.
    • (1992) Oncogene , vol.7 , pp. 1201-1206
    • Itoh, F.1    Ishizaka, Y.2    Tahira, T.3    Yamamoto, M.4    Miya, A.5    Imai, K.6    Yachi, A.7    Takai, S.8    Sugimura, T.9    Nagao, M.10
  • 21
    • 0025037502 scopus 로고
    • GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase
    • Jackson S.P., MacDonald J.J., Lees-Miller S., Tjian R. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell. 63:1990;155-165.
    • (1990) Cell , vol.63 , pp. 155-165
    • Jackson, S.P.1    MacDonald, J.J.2    Lees-Miller, S.3    Tjian, R.4
  • 23
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin A.W., Barradas M., Stone J.C., van Aelst L., Serrano M., Lowe S.W. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev. 12:1998;3008-3019.
    • (1998) Genes Dev. , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    Van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 24
    • 0025021229 scopus 로고
    • Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues
    • McMahon A.P., Champion J.E., McMahon J.A., Sukhatme V.P. Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues. Development. 108:1990;281-287.
    • (1990) Development , vol.108 , pp. 281-287
    • McMahon, A.P.1    Champion, J.E.2    McMahon, J.A.3    Sukhatme, V.P.4
  • 25
    • 0032547951 scopus 로고    scopus 로고
    • A 5′-CG-3′-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residues
    • Munnes M., Patrone G., Schmitz B., Romeo G., Doerfler W. A 5′-CG-3′-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residues. Oncogene. 17:1998;2573-2583.
    • (1998) Oncogene , vol.17 , pp. 2573-2583
    • Munnes, M.1    Patrone, G.2    Schmitz, B.3    Romeo, G.4    Doerfler, W.5
  • 26
    • 0007912235 scopus 로고
    • Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells
    • Nakagawa T., Mabry M., de Bustros A., Ihle J.N., Nelkin B.D., Baylin S.B. Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells. Proc. Natl. Acad. Sci. USA. 84:1987;5923-5927.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 5923-5927
    • Nakagawa, T.1    Mabry, M.2    De Bustros, A.3    Ihle, J.N.4    Nelkin, B.D.5    Baylin, S.B.6
  • 27
    • 0027374562 scopus 로고
    • Expression of the c-ret proto-oncogene during mouse embryogenesis
    • Pachnis V., Mankoo B., Costantini F. Expression of the c-ret proto-oncogene during mouse embryogenesis. Development. 119:1993;1005-1017.
    • (1993) Development , vol.119 , pp. 1005-1017
    • Pachnis, V.1    Mankoo, B.2    Costantini, F.3
  • 28
    • 0033563301 scopus 로고    scopus 로고
    • Other neurotrophic factors: Glial cell line-derived neurotrophic factor (GDNF)
    • Saarma M., Sariola H. Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF). Microsc. Res. Tech. 45:1999;292-302.
    • (1999) Microsc. Res. Tech. , vol.45 , pp. 292-302
    • Saarma, M.1    Sariola, H.2
  • 29
    • 0032996518 scopus 로고    scopus 로고
    • Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2
    • Santiago F.S., Lowe H.C., Day F.L., Chesterman C.N., Khachigian L.M. Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2. Am. J. Pathol. 154:1999;937-944.
    • (1999) Am. J. Pathol. , vol.154 , pp. 937-944
    • Santiago, F.S.1    Lowe, H.C.2    Day, F.L.3    Chesterman, C.N.4    Khachigian, L.M.5
  • 30
    • 0025000865 scopus 로고
    • The ret proto-oncogene is consistently expressed in human pheochromocytomas and thyroid medullary carcinomas
    • Santoro M., Rosati R., Grieco M., Berlingieri M.T., D'Amato G.L., de Franciscis V., Fusco A. The ret proto-oncogene is consistently expressed in human pheochromocytomas and thyroid medullary carcinomas. Oncogene. 5:1990;1595-1598.
    • (1990) Oncogene , vol.5 , pp. 1595-1598
    • Santoro, M.1    Rosati, R.2    Grieco, M.3    Berlingieri, M.T.4    D'Amato, G.L.5    De Franciscis, V.6    Fusco, A.7
  • 31
    • 0032533875 scopus 로고    scopus 로고
    • CAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1)
    • Silverman E.S., Du J., Williams A.J., Wadgaonkar R., Drazen J.M., Collins T. cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem. J. 336:(Pt 1):1998;183-189.
    • (1998) Biochem. J. , vol.336 , Issue.PART 1 , pp. 183-189
    • Silverman, E.S.1    Du, J.2    Williams, A.J.3    Wadgaonkar, R.4    Drazen, J.M.5    Collins, T.6
  • 32
    • 0029090347 scopus 로고
    • A regulatory element in the human interleukin 2 gene promoter is a binding site for the zinc finger proteins Sp1 and EGR-1
    • Skerka C., Decker E.L., Zipfel P.F. A regulatory element in the human interleukin 2 gene promoter is a binding site for the zinc finger proteins Sp1 and EGR-1. J. Biol. Chem. 270:1995;22500-22506.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22500-22506
    • Skerka, C.1    Decker, E.L.2    Zipfel, P.F.3
  • 33
  • 35
    • 0029851837 scopus 로고    scopus 로고
    • Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin
    • Takaya K., Yoshimasa T., Arai H., Tamura N., Miyamoto Y., Itoh H., Nakao K. Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin. J. Mol. Med. 74:1996;617-621.
    • (1996) J. Mol. Med. , vol.74 , pp. 617-621
    • Takaya, K.1    Yoshimasa, T.2    Arai, H.3    Tamura, N.4    Miyamoto, Y.5    Itoh, H.6    Nakao, K.7
  • 36
    • 0033137330 scopus 로고    scopus 로고
    • Mammalian Kruppel-like transcription factors: More than just a pretty finger
    • Turner J., Crossley M. Mammalian Kruppel-like transcription factors: more than just a pretty finger. Trends Biochem. Sci. 24:1999;236-240.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 236-240
    • Turner, J.1    Crossley, M.2
  • 37
    • 0035824547 scopus 로고    scopus 로고
    • An early growth response protein (Egr) 1 cis-element is required for gonadotropin-releasing hormone-induced mitogen-activated protein kinase phosphatase 2 gene expression
    • Zhang T., Wolfe M.W., Roberson M.S. An early growth response protein (Egr) 1 cis-element is required for gonadotropin-releasing hormone-induced mitogen-activated protein kinase phosphatase 2 gene expression. J. Biol. Chem. 276:2001;45604-45613.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45604-45613
    • Zhang, T.1    Wolfe, M.W.2    Roberson, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.