Identification of the Substrate Specificity-conferring Amino Acid Residues of 4-Coumarate:Coenzyme A Ligase Allows the Rational Design of Mutant Enzymes with New Catalytic Properties

Journal of Biological Chemistry

Volumn 276, Issue 29, 2001, Pages 26893-26897

  Stuible, Hans Peter ^b   Kombrink, Erich ^a  

^a MAX PLANCK INSTITUTE FOR PLANT BREEDING RESEARCH   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL ACTIVATION; CRYSTAL STRUCTURE; SUBSTITUTION REACTIONS; SUBSTRATES;

FERULATE;

ENZYMES;

AMINO ACID; CAFFEIC ACID; COUMARIC ACID; FERULIC ACID; GRAMICIDIN S SYNTHETASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; LYSINE; METHIONINE; PHENYLALANINE; 4 COUMARATE COA LIGASE; 4-COUMARATE-COA LIGASE; PRIMER DNA;

AMINO ACID SUBSTITUTION; ARABIDOPSIS; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

ARABIDOPSIS; ARABIDOPSIS THALIANA;

AMINO ACID SEQUENCE; ARABIDOPSIS; BASE SEQUENCE; CATALYSIS; COENZYME A LIGASES; DNA PRIMERS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0035920183     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100355200     Document Type: Article

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