Production of growth related oncogene protein-α in human umbilical vein endothelial cells stimulated with soluble interleukin-6 receptor-α: Role of signal transducers, janus kinase 2 and mitogen-activated kinase kinase

Life Sciences

Volumn 70, Issue 26, 2002, Pages 3179-3190

  Matsumiya, Tomoh ^a   Imaizumi, Tadaatsu ^a   Itaya, Hiroyuki ^a   Shibata, Takeo ^a   Yoshida, Hidemi ^a   Sakaki, Hirotaka ^a   Kimura, Hiroto ^a   Satoh, Kei ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

GRO ; Human umbilical vein endothelial cells; JAK2; MEK SHP 2; Soluble IL 6 receptor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; GROWTH RELATED ONCOGENE PROTEIN; INTERLEUKIN 6 RECEPTOR; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; ONCOPROTEIN; PROTEIN TYROSINE PHOSPHATASE; STAT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; UMBILICAL VEIN;

CELLS, CULTURED; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; GROWTH SUBSTANCES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JANUS KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, INTERLEUKIN-6; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; UMBILICAL VEINS;

JANUS;

EID: 0037123715     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01560-6     Document Type: Article

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