4′-Arylpyrrolomorphinans: Effect of a pyrrolo-N-benzyl substituent in enhancing δ-opioid antagonist activity

Journal of Medicinal Chemistry

Volumn 45, Issue 2, 2002, Pages 537-540

  Srivastava, Sanjay K ^a   Husbands, Stephen M ^b   Aceto, Mario D ^d   Miller, Carl N ^c   Traynor, John R ^c   Lewis, John W ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b University of Bath   (United Kingdom)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR ANTAGONIST; MORPHINAN DERIVATIVE; NALTRINDOLE; PYRROLOMORPHINAN DERIVATIVE; STYRENE; UNCLASSIFIED DRUG; DELTA OPIATE RECEPTOR; LIGAND; NARCOTIC ANTAGONIST;

ARTICLE; BINDING SITE; DRUG EFFECT; DRUG ISOLATION; IMMUNOSTIMULATION; LIPOPHILICITY; MOLECULAR INTERACTION; NONHUMAN; RECEPTOR AFFINITY; STOMACH MOTILITY; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CHO CELL; DRUG ANTAGONISM; DRUG POTENTIATION; GENETIC TRANSFECTION; HAMSTER; HUMAN; IN VITRO STUDY; MALE; METABOLISM; MOUSE; RADIOASSAY; SEIZURE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VAS DEFERENS;

ANIMALS; CHO CELLS; CRICETINAE; HUMANS; LIGANDS; MALE; MICE; MORPHINANS; NARCOTIC ANTAGONISTS; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, DELTA; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; VAS DEFERENS;

EID: 0037122457     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010841w     Document Type: Article

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